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    v1.0.28
    OpenPayerBilling CodesAbnormal findings on examination of blood, without diagnosisICD-10-CM r76-other-abnormal-immunological-findings
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    ICD-10-CM Code For Other Abnormal Immunological Findings In Serum: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group R76 includes nonspecific abnormal immunological findings in serum, such as unexplained positive serologic tests or elevated immunologic markers without a confirmed diagnosis. These ICD-10-CM diagnosis codes are used to document clinical scenarios where laboratory immunologic abnormalities are detected but a specific infectious, autoimmune, or systemic disease has not been established, capturing disease uncertainty and the need for further workup. Accurate coding within the ICD-10-CM R76 group supports proper claim adjudication and complete clinical documentation for appropriate reimbursement.

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    ICD-10-CM R76: Other Abnormal Immunological Findings In Serum Overview

    This code group captures abnormal immunological laboratory findings identified in serum testing that do not yet correspond to a definitive disease diagnosis. The abnormalities reflect immune system markers such as nonspecific antibodies or serologic test results that may prompt further evaluation. Accurate coding matters for reimbursement because it documents medical necessity for testing and follow-up care.

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    When to Use

    Use a code from this group when laboratory immunologic abnormalities are documented but no confirmed infectious, autoimmune, or systemic diagnosis has been established. These codes apply when the clinical record indicates abnormal serum immunologic test results that require further evaluation or monitoring.

    ICD-10-CM Codes

    6 rows

    ICD-10-CM CodeDescription
    R76.0Raised antibody titer
    R76.11Nonspecific reaction to tuberculin skin test without active tuberculosis
    R76.12Nonspecific reaction to cell mediated immunity measurement of gamma interferon antigen response without active tuberculosis
    R76.81Abnormal rheumatoid factor and anti-citrullinated protein antibody without rheumatoid arthritis
    R76.89Other specified abnormal immunological findings in serum
    R76.9Abnormal immunological finding in serum, unspecified

    DRG Codes

    6 rows

    DRG CodeDescription
    177Respiratory Infections and Inflammations with MCC
    178Respiratory Infections and Inflammations with CC
    179Respiratory Infections and Inflammations without CC/MCC
    814Reticuloendothelial and Immunity Disorders with MCC
    815Reticuloendothelial and Immunity Disorders with CC
    816Reticuloendothelial and Immunity Disorders without CC/MCC

    Related Codes

    R70-ELEVATED-ERYTHROCYTE-SEDIMENTATION-RATE

    ICD-10-CM Code For Elevated Erythrocyte Sedimentation Rate And Abnormality Of Plasma Viscosity: Group Overview

    R71-ABNORMALITY-OF-RED-BLOOD-CELLS

    ICD-10-CM Code For Abnormality Of Red Blood Cells: Group Overview

    R73-ELEVATED-BLOOD-GLUCOSE-LEVEL

    ICD-10-CM Code For Elevated Blood Glucose Level: Group Overview

    R74-ABNORMAL-SERUM-ENZYME-LEVELS

    ICD-10-CM Code For Abnormal Serum Enzyme Levels: Group Overview

    R75-INCONCLUSIVE-HIV-LABORATORY-EVIDENCE

    ICD-10-CM Code For Inconclusive Laboratory Evidence Of Human Immunodeficiency Virus: Group Overview

    R77-OTHER-ABNORMALITIES-OF-PLASMA-PROTEINS

    ICD-10-CM Code For Other Abnormalities Of Plasma Proteins: Group Overview

    R78-FINDINGS-OF-DRUGS-AND-OTHER-SUBSTANCES

    ICD-10-CM Code For Findings Of Drugs And Other Substances Not Normally Found In Blood: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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