ICD-10-CM Code For Other Respiratory Conditions Originating In The Perinatal Period: Group Overview

The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group P28 includes neonatal respiratory disorders originating in the perinatal period such as transient tachypnea of the newborn, persistent pulmonary hypertension of the newborn, and other specified respiratory conditions affecting newborns. These ICD-10-CM diagnosis codes are used to document clinical scenarios involving respiratory compromise in the immediate newborn period, capturing severity, need for respiratory support, and associated complications. Accurate coding within the ICD-10-CM P28 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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ICD-10-CM P28: Other Respiratory Conditions Originating In The Perinatal Period Overview

This group includes neonatal respiratory conditions that originate during the perinatal period and affect the newborn's breathing and lung function. It covers disorders such as transient neonatal respiratory distress, persistent fetal circulation, and other specified perinatal respiratory problems. Accurate coding is important for complete clinical documentation and can affect claim adjudication and appropriate reimbursement.

When to Use

Use codes from this group when a newborn presents with respiratory signs or diagnoses documented as originating in the perinatal period. Select the specific code that reflects the documented condition, its severity, and any associated complications or need for respiratory support.

ICD-10-CM Codes

19 rows

ICD-10-CM Code	Description
P28.0	Primary atelectasis of newborn
P28.10	Unspecified atelectasis of newborn
P28.11	Resorption atelectasis without respiratory distress syndrome
P28.19	Other atelectasis of newborn
P28.2	Cyanotic attacks of newborn
P28.30	Primary sleep apnea of newborn, unspecified
P28.31	Primary central sleep apnea of newborn
P28.32	Primary obstructive sleep apnea of newborn
P28.33	Primary mixed sleep apnea of newborn
P28.39	Other primary sleep apnea of newborn
P28.40	Unspecified apnea of newborn
P28.41	Central neonatal apnea of newborn
P28.42	Obstructive apnea of newborn
P28.43	Mixed neonatal apnea of newborn
P28.49	Other apnea of newborn
P28.5	Respiratory failure of newborn
P28.81	Respiratory arrest of newborn
P28.89	Other specified respiratory conditions of newborn
P28.9	Respiratory condition of newborn, unspecified

DRG Codes

3 rows

DRG Code	Description
791	Prematurity with Major Problems
793	Full Term Neonate with Major Problems
794	Neonate with Other Significant Problems

Typical Clinical Scenarios

A term or preterm neonate in the delivery room or neonatal intensive care unit with persistent tachypnea, expiratory grunting, intercostal retractions, and oxygen requirement shortly after birth following meconium-stained amniotic fluid. The infant is evaluated for airway obstruction and parenchymal lung injury from meconium aspiration, and chest radiograph shows patchy bilateral airspace disease consistent with aspiration pneumonitis; a code from this group is assigned to capture the respiratory condition related to perinatal meconium exposure. Typical codes: P28.0, P28.1.
A late-preterm infant develops episodic cyanotic spells with apnea and bradycardia several days after birth while receiving routine newborn care; evaluation excludes sepsis and structural cardiac disease, and clinical assessment attributes recurrent apnea to immaturity of respiratory control or central apnea of the newborn requiring monitoring and sometimes respiratory support. A perinatal-period respiratory diagnosis is used to document the central or mixed apnea contributing to the cardiorespiratory events. Typical codes: P28.3, P28.81.
A neonate born after prolonged oligohydramnios has persistent pulmonary hypoplasia, chronic oxygen dependence, and difficulty weaning from respiratory support beyond the immediate newborn period; the infant is followed as an ongoing respiratory comorbidity complicating the perinatal course and influencing feeding and growth plans. A code from this group is assigned to represent the chronic developmental respiratory disorder originating in the perinatal period. Typical codes: P28.2, P28.5.

Related Codes

P19-METABOLIC-ACIDEMIA-IN-NEWBORN

ICD-10-CM Code For Metabolic Acidemia In Newborn: Group Overview

P22-RESPIRATORY-DISTRESS-OF-NEWBORN

ICD-10-CM Code For Respiratory Distress Of Newborn: Group Overview

P23-CONGENITAL-PNEUMONIA

ICD-10-CM Code For Congenital Pneumonia: Group Overview

P24-NEONATAL-ASPIRATION

ICD-10-CM Code For Neonatal Aspiration: Group Overview

P25-INTERSTITIAL-EMPHYSEMA-AND-RELATED-CONDITIONS

ICD-10-CM Code For Interstitial Emphysema And Related Conditions Originating In The Perinatal Period: Group Overview

P26-PULMONARY-HEMORRHAGE-PERINATAL

ICD-10-CM Code For Pulmonary Hemorrhage Originating In The Perinatal Period: Group Overview

P27-CHRONIC-RESPIRATORY-DISEASE-PERINATAL

ICD-10-CM Code For Chronic Respiratory Disease Originating In The Perinatal Period: Group Overview

P29-CARDIOVASCULAR-DISORDERS-PERINATAL

ICD-10-CM Code For Cardiovascular Disorders Originating In The Perinatal Period: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-CM Codes

19 rows

ICD-10-CM Code	Description
P28.0	Primary atelectasis of newborn
P28.10	Unspecified atelectasis of newborn
P28.11	Resorption atelectasis without respiratory distress syndrome
P28.19	Other atelectasis of newborn
P28.2	Cyanotic attacks of newborn
P28.30	Primary sleep apnea of newborn, unspecified
P28.31	Primary central sleep apnea of newborn
P28.32	Primary obstructive sleep apnea of newborn
P28.33	Primary mixed sleep apnea of newborn
P28.39	Other primary sleep apnea of newborn
P28.40	Unspecified apnea of newborn
P28.41	Central neonatal apnea of newborn
P28.42	Obstructive apnea of newborn
P28.43	Mixed neonatal apnea of newborn
P28.49	Other apnea of newborn
P28.5	Respiratory failure of newborn
P28.81	Respiratory arrest of newborn
P28.89	Other specified respiratory conditions of newborn
P28.9	Respiratory condition of newborn, unspecified

DRG Codes

3 rows

DRG Code	Description
791	Prematurity with Major Problems
793	Full Term Neonate with Major Problems
794	Neonate with Other Significant Problems

Typical Clinical Scenarios

A term or preterm neonate in the delivery room or neonatal intensive care unit with persistent tachypnea, expiratory grunting, intercostal retractions, and oxygen requirement shortly after birth following meconium-stained amniotic fluid. The infant is evaluated for airway obstruction and parenchymal lung injury from meconium aspiration, and chest radiograph shows patchy bilateral airspace disease consistent with aspiration pneumonitis; a code from this group is assigned to capture the respiratory condition related to perinatal meconium exposure. Typical codes: P28.0, P28.1.
A late-preterm infant develops episodic cyanotic spells with apnea and bradycardia several days after birth while receiving routine newborn care; evaluation excludes sepsis and structural cardiac disease, and clinical assessment attributes recurrent apnea to immaturity of respiratory control or central apnea of the newborn requiring monitoring and sometimes respiratory support. A perinatal-period respiratory diagnosis is used to document the central or mixed apnea contributing to the cardiorespiratory events. Typical codes: P28.3, P28.81.
A neonate born after prolonged oligohydramnios has persistent pulmonary hypoplasia, chronic oxygen dependence, and difficulty weaning from respiratory support beyond the immediate newborn period; the infant is followed as an ongoing respiratory comorbidity complicating the perinatal course and influencing feeding and growth plans. A code from this group is assigned to represent the chronic developmental respiratory disorder originating in the perinatal period. Typical codes: P28.2, P28.5.

Related Codes

P19-METABOLIC-ACIDEMIA-IN-NEWBORN

ICD-10-CM Code For Metabolic Acidemia In Newborn: Group Overview

P22-RESPIRATORY-DISTRESS-OF-NEWBORN

ICD-10-CM Code For Respiratory Distress Of Newborn: Group Overview

P23-CONGENITAL-PNEUMONIA

ICD-10-CM Code For Congenital Pneumonia: Group Overview

P24-NEONATAL-ASPIRATION

ICD-10-CM Code For Neonatal Aspiration: Group Overview

P25-INTERSTITIAL-EMPHYSEMA-AND-RELATED-CONDITIONS

ICD-10-CM Code For Interstitial Emphysema And Related Conditions Originating In The Perinatal Period: Group Overview

P26-PULMONARY-HEMORRHAGE-PERINATAL

ICD-10-CM Code For Pulmonary Hemorrhage Originating In The Perinatal Period: Group Overview

P27-CHRONIC-RESPIRATORY-DISEASE-PERINATAL

ICD-10-CM Code For Chronic Respiratory Disease Originating In The Perinatal Period: Group Overview

P29-CARDIOVASCULAR-DISORDERS-PERINATAL

ICD-10-CM Code For Cardiovascular Disorders Originating In The Perinatal Period: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-CM Code For Other Respiratory Conditions Originating In The Perinatal Period: Group Overview

Sign up for ICD-10-CM Code For Other Respiratory Conditions Originating In The Perinatal Period: Group Overview policy alerts

ICD-10-CM P28: Other Respiratory Conditions Originating In The Perinatal Period Overview

ICD-10-CM Code For Other Respiratory Conditions Originating In The Perinatal Period: Group Overview

Sign up for ICD-10-CM Code For Other Respiratory Conditions Originating In The Perinatal Period: Group Overview policy alerts

ICD-10-CM P28: Other Respiratory Conditions Originating In The Perinatal Period Overview

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which neonatal respiratory disorders are included in ICD-10-CM group P28?

How do codes in the P28 group support reimbursement and billing?

Which specific codes describe types of apnea in newborns within P28?

What P28 codes cover atelectasis in the newborn?

Which DRGs are related to the P28 diagnosis group?

References

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which neonatal respiratory disorders are included in ICD-10-CM group P28?

How do codes in the P28 group support reimbursement and billing?

Which specific codes describe types of apnea in newborns within P28?

What P28 codes cover atelectasis in the newborn?

Which DRGs are related to the P28 diagnosis group?

References