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    v1.0.28
    OpenPayerBilling CodesRespiratory and cardiovascular disorders specific to the perinatal periodICD-10-CM p27-chronic-respiratory-disease-perinatal
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    ICD-10-CM Code For Chronic Respiratory Disease Originating In The Perinatal Period: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group P27 includes chronic respiratory disorders originating in the perinatal period such as bronchopulmonary dysplasia, chronic respiratory disease due to lung hypoplasia, and other sequelae of neonatal respiratory failure that affect long-term pulmonary function. These ICD-10-CM diagnosis codes are used to document ongoing respiratory morbidity in infants and children, capturing disease severity, organ involvement, or clinical complexity relevant to perinatal pulmonary conditions. Accurate coding within the ICD-10-CM P27 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM P27: Chronic Respiratory Disease Originating In The Perinatal Period Overview

    The ICD-10-CM P27 group represents chronic respiratory disorders that originate in the perinatal period, including conditions such as chronic respiratory disease due to lung hypoplasia, bronchopulmonary dysplasia, and other sequelae of neonatal respiratory distress. These diagnoses target the neonatal respiratory system and often reflect long-term pulmonary morbidity following preterm birth or perinatal lung injury. Accurate coding matters for documenting clinical complexity and supporting appropriate reimbursement for ongoing neonatal and pediatric respiratory care.

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    When to Use

    Use a code from this group when an infant or child has chronic respiratory disease attributed to perinatal events, neonatal respiratory distress, or documented lung hypoplasia with ongoing pulmonary impairment. These codes apply when the chronic respiratory condition is the result of perinatal onset and is being managed or followed in clinical documentation.

    ICD-10-CM Codes

    4 rows

    ICD-10-CM CodeDescription
    P27.0Wilson-Mikity syndrome
    P27.1Bronchopulmonary dysplasia originating in the perinatal period
    P27.8Other chronic respiratory diseases originating in the perinatal period
    P27.9Unspecified chronic respiratory disease originating in the perinatal period

    DRG Codes

    3 rows

    DRG CodeDescription
    196Interstitial Lung Disease with MCC
    197Interstitial Lung Disease with CC
    198Interstitial Lung Disease without CC/MCC

    Typical Clinical Scenarios

    • A premature infant born at 28 weeks gestation with a history of surfactant therapy and prolonged mechanical ventilation in the NICU develops persistent oxygen requirement and radiographic evidence of chronic interstitial changes and bronchovascular thickening at 36 weeks corrected age. The infant returns for follow‑up with tachypnea, intermittent wheeze, and need for supplemental oxygen beyond the neonatal period; a chronic respiratory disorder originating in the perinatal period is assigned to capture ongoing lung disease related to prematurity and neonatal respiratory support. Typical codes: P27.0, P27.1
    • A term newborn who experienced meconium aspiration and required extracorporeal membrane oxygenation (ECMO) during the first week of life is evaluated at 3 months of age for failure to wean from oxygen and recurrent hospitalizations for lower respiratory tract infections. The chronic respiratory impairment is attributed to the perinatal inhalational injury and prolonged cardiopulmonary support, prompting assignment of a code from this group to document the long‑term respiratory sequelae related to the perinatal event. Typical codes: P27.8, P27.9
    • An infant with congenital diaphragmatic hernia repaired shortly after birth who had prolonged ventilator dependence and pulmonary hypoplasia is followed in specialty clinic for chronic hypoxemia, pulmonary hypertension, and developmental feeding problems. The ongoing respiratory disability is recorded as a respiratory disorder of perinatal origin to reflect chronic lung disease secondary to the neonatal structural and ventilatory insults and to guide continuity of care and surveillance. Typical codes: P27.0, P27.8

    Related Codes

    P19-METABOLIC-ACIDEMIA-IN-NEWBORN

    ICD-10-CM Code For Metabolic Acidemia In Newborn: Group Overview

    P22-RESPIRATORY-DISTRESS-OF-NEWBORN

    ICD-10-CM Code For Respiratory Distress Of Newborn: Group Overview

    P23-CONGENITAL-PNEUMONIA

    ICD-10-CM Code For Congenital Pneumonia: Group Overview

    P24-NEONATAL-ASPIRATION

    ICD-10-CM Code For Neonatal Aspiration: Group Overview

    P25-INTERSTITIAL-EMPHYSEMA-AND-RELATED-CONDITIONS

    ICD-10-CM Code For Interstitial Emphysema And Related Conditions Originating In The Perinatal Period: Group Overview

    P26-PULMONARY-HEMORRHAGE-PERINATAL

    ICD-10-CM Code For Pulmonary Hemorrhage Originating In The Perinatal Period: Group Overview

    P28-OTHER-RESPIRATORY-PERINATAL-CONDITIONS

    ICD-10-CM Code For Other Respiratory Conditions Originating In The Perinatal Period: Group Overview

    P29-CARDIOVASCULAR-DISORDERS-PERINATAL

    ICD-10-CM Code For Cardiovascular Disorders Originating In The Perinatal Period: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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