Summary & Overview
HCPCS Q4382: Advograft dual graft, per square centimeter
HCPCS Level II code Q4382 identifies Advograft dual, a biologic graft product billed per square centimeter as an add-on supply to a primary surgical procedure. Nationally, add-on supply codes like Q4382 matter because they enable itemized reporting of implantable or adjunct materials used in operative care, supporting transparency in procedural billing and supply utilization. Payers commonly process add-on HCPCS codes separately from the base procedure, impacting claim edit logic and payment pathways.
Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of the code’s clinical context and service settings, common modifiers used in claims, and the typical billing considerations for add-on biologic graft supplies. The publication also highlights expected payer handling patterns and the implications for claim adjudication and documentation practices at a national level.
This summary is intended to orient coders, billing managers, and policy analysts to the purpose of Q4382, where it is used, and what to expect when this per-square-centimeter graft product is reported in conjunction with primary surgical procedures. Data not available in the input is noted where applicable.
Billing Code Overview
HCPCS Level II code Q4382 describes Advograft dual, billed per square centimeter as an add-on supply to be listed separately in addition to a primary procedure. The item denotes a biologic graft product provided in square-centimeter units and is intended for use as an adjunct during surgical procedures that require graft material.
Service type: Biologic graft supply
Typical site of service: Hospital operating room, outpatient surgery center, or other procedural settings where surgical grafting is performed
Clinical & Coding Specifications
Clinical Context
A typical patient is a middle-aged adult with a chronic, non-healing soft tissue wound (for example, a large traumatic degloving injury or a surgical site with significant tissue loss) requiring advanced biologic grafting to achieve durable soft tissue coverage. In the operating room or a procedure suite, the surgeon debrides nonviable tissue, achieves hemostasis, and prepares the wound bed. Q4382 (Advograft dual, per square centimeter) is applied as an add-on biologic dermal matrix over the prepared wound to provide structural scaffold and promote revascularization. The product is measured and billed per square centimeter in addition to the primary procedure that establishes wound coverage (for example, grafting or flap procedure). Typical workflow steps include wound assessment, photography and measurement, operative or bedside debridement, placement of the Advograft material sized to the wound area, fixation as needed, and documentation of product type, square centimeters used, and the primary procedure to which the add-on graft applies. Common sites of service include hospital operating rooms, ambulatory surgery centers, and specialized wound care procedure suites.
Coding Specifications
| Modifier | Description | When to Use |
|---|---|---|
00 | No modifier (default) | Used when no special circumstances or payer-specific modifiers apply; report the code as listed. |