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    v1.0.30
    OpenPayerBilling CodesTemporary CodesHCPCS hcpcs-level-ii-q5132-adalimumab-afzb-abrilada-10mg-injection
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    HCPCS Level II Q5132: Injection, adalimumab-afzb (Abrilada), 10 mg

    HCPCS Level II code Q5132 identifies the injection of adalimumab-afzb (Abrilada), a 10 mg biosimilar formulation of adalimumab used for subcutaneous biologic therapy; the service represents a biologic medication administration/product and is typically billed for subcutaneous injection in outpatient clinics, physician offices, or infusion/biologic therapy centers.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult with an immune-mediated inflammatory disease such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, or plaque psoriasis who requires subcutaneous biologic therapy. The patient presents to an infusion or injection clinic, specialty pharmacy clinic, or office-based procedure room for administration of a biosimilar adalimumab product. The service documented by Q5132 represents a 10 mg prefilled-syringe or pen dose of adalimumab-afzb (Abrilada) used for subcutaneous injection.

    The clinical workflow includes verification of the medication order and dose, allergy and infection screening, patient education regarding self-administration if discharge to home is planned, preparation of the injection by a licensed clinician or trained staff, administration via subcutaneous injection, and post-injection observation for adverse reactions. Documentation includes medication lot and expiration, administration site, route, dose, informed consent or teaching, and any immediate adverse effects. Billing uses Q5132 to report the specific HCPCS Level II supply for the 10 mg adalimumab-afzb product when applicable per payer guidance.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    96372Therapeutic, prophylactic, or diagnostic injection (subcutaneous or intramuscular)Common code for administration of a subcutaneous medication when a separate administration fee is billed alongside the drug HCPCS code.
    99001Handling and/or conveyance of diagnostic specimens (clinical lab procedures) (Note: some payers have specific codes for medication handling)May be used by some facilities for special handling or preparation services related to biologic agents per payer rules.
    99070Supplies and materials (except spectacles) provided by the physician over and above those usually included with the office visitUsed to report disposable supplies associated with injection administration when payer allows.
    96360Intravenous infusion, hydration; initial, 31 minutes to 1 hourNot typical for subcutaneous injection, included when infusion services occur in the same visit.
    99406Smoking and tobacco use cessation counseling visit; intermediate, greater than 3 minutes up to 10 minutesExample of an ancillary counseling CPT that may be provided during a medication management visit (billing depends on documentation and payer policy).

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RC0000X
    2080P0207X
    363L00000X
    363A00000X
    207L00000X
    2088F0040X
    2279C0205X
    133VN1301X

    Related ICD-10-CM Codes

    20 rows

    ICD-10-CM CodeDescription
    E11.9Type 2 diabetes mellitus without complications
    H10.9Unspecified conjunctivitis
    H40.9Unspecified glaucoma
    I10Essential (primary) hypertension
    K50.90Crohn's disease, unspecified, without complications
    K51.90Ulcerative colitis, unspecified, without complications
    L40.0Psoriasis vulgaris
    L40.9Psoriasis, unspecified
    M05.79Rheumatoid arthritis with rheumatoid factor of multiple sites without organ or systems involvement
    M06.4Inflammatory polyarthropathy

    Showing 1–10 of 20

    Related Codes

    HCPCS-LEVEL-II-Q4139-INJECTABLE-AMNIOMATRIX-BIODMATRIX-1-CC

    HCPCS Q4139: Amniomatrix or Biodmatrix, Injectable, 1 cc

    HCPCS-LEVEL-II-Q4256-AREA-BASED-PROCEDURAL-ADD-ON-PER-SQ-CM

    HCPCS Q4256: MLG-complete Skin Graft Material, Per Sq Cm

    HCPCS-Q0035-CARDIOKYMOGRAPHY-CARDIAC-MOTION-RECORDING

    HCPCS Level II Q0035: Cardiokymography

    HCPCS-Q0081-INFUSION-THERAPY-NON-CHEMOTHERAPEUTIC-PER-VISIT

    HCPCS Level II Q0081: Infusion Therapy, Non‑Chemotherapeutic, Per Visit

    HCPCS-Q0083-CHEMOTHERAPY-NON-INFUSION-ADMINISTRATION

    HCPCS Q0083: Chemotherapy Administration, Non-Infusion Methods

    HCPCS-Q0084-CHEMOTHERAPY-INFUSION-ADMINISTRATION-PER-VISIT

    HCPCS Q0084: Chemotherapy Infusion Administration, Per Visit

    HCPCS-Q0085-CHEMOTHERAPY-INFUSION-PLUS-OTHER-TECHNIQUES-PER-VISIT

    HCPCS Q0085: Chemotherapy Infusion Plus Other Technique(s), Per Visit

    HCPCS-Q0091-PAP-SMEAR-SPECIMEN-COLLECTION-TRANSPORT

    HCPCS Q0091: Screening Papanicolaou Smear Collection and Transport

    HCPCS-Q0092-PORTABLE-XRAY-EQUIPMENT-SETUP

    HCPCS Q0092: Set-up Portable X-ray Equipment

    HCPCS-Q0111-WET-MOUNT-VAGINAL-CERVICAL-SKIN-SPECIMENS

    HCPCS Q0111: Wet Mount Preparations of Vaginal, Cervical, or Skin Specimens

    Showing 1–10 of 629

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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