HCPCS Level II J7308: Aminolevulinic Acid HCl 20% Topical, 354 mg
HCPCS Level II code J7308 describes aminolevulinic acid HCl 20% in a single unit topical dosage form (354 mg) used for photodynamic therapy of cutaneous lesions; service type is topical photosensitizer application and the typical site of service is outpatient dermatology or ambulatory procedure settings where topical photodynamic therapy is performed.
For related coverage guidance, see recent payer policy updates: Epithelial Cell Cytology in Breast Cancer Risk Assessment, Chemotherapy Observation or Inpatient Hospitalization (for New Mexico Only), Umbilical Cord Blood Harvesting and Storage for Future Use (for Indiana Only).
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National Reimbursement Benchmarks
Commercial reimbursement for J7308 centers around a BUCA average commercial rate of $385.30, with individual payer means ranging above and below that benchmark. Blue Cross Blue Shield (BCBS) and Cigna show means near the BUCA level ($385.60 and $404.70 respectively), while UnitedHealth Group posts a higher mean at $437.00 and Aetna is notably lower at $313.40. This positions BUCA as a useful midpoint for commercial expectations, with UnitedHealth Group skewing higher and Aetna skewing lower in national commercial pricing.
Dispersion measured by the interquartile gap (P75 minus P25) highlights variation across payers: Aetna’s IQR is $205.60, BCBS’s IQR is $37.00, BUCA’s IQR is $56.20, Cigna’s IQR is $9.00, and UnitedHealth Group’s IQR is $30.50. Cigna exhibits the tightest spread ($9.00), indicating concentrated commercial rates, while Aetna shows the widest spread ($205.60), indicating substantial variability in contracted rates.