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    v1.0.28
    OpenPayerBilling CodesDemyelinating diseases of the central nervous systemICD-10-CM g36-other-acute-disseminated-demyelination
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    ICD-10-CM Code For Other Acute Disseminated Demyelination: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group G36 includes acute disseminated demyelinating conditions of the central nervous system such as acute disseminated encephalomyelitis and other nonmultiple sclerosis demyelination syndromes that present with new focal or multifocal neurologic deficits. These ICD-10-CM diagnosis codes are used to document clinical scenarios involving acute immune‑mediated myelin injury with variable severity, multifocal central nervous system involvement, and potential need for acute therapy or hospitalization. Accurate coding within the ICD-10-CM G36 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM G36: Other Acute Disseminated Demyelination Overview

    The ICD-10-CM G36 code group captures acute demyelinating events that affect the central nervous system outside of classic multiple sclerosis presentations. These diagnoses represent immune-mediated loss of myelin in the brain and spinal cord and can cause neurologic deficits such as weakness, sensory loss, and visual disturbance. Accurate coding matters for appropriate claim adjudication and to reflect clinical complexity for reimbursement.

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    When to Use

    Use a code from this group when documentation describes an acute disseminated demyelinating event affecting the brain or spinal cord that is not coded as multiple sclerosis. Assign these codes for clinical encounters capturing initial presentation, acute management, or ongoing care specifically linked to acute disseminated demyelination.

    ICD-10-CM Codes

    4 rows

    ICD-10-CM CodeDescription
    G36.0Neuromyelitis optica [Devic]
    G36.1Acute and subacute hemorrhagic leukoencephalitis [Hurst]
    G36.8Other specified acute disseminated demyelination
    G36.9Acute disseminated demyelination, unspecified

    DRG Codes

    6 rows

    DRG CodeDescription
    058Multiple Sclerosis and Cerebellar Ataxia with MCC
    059Multiple Sclerosis and Cerebellar Ataxia with CC
    060Multiple Sclerosis and Cerebellar Ataxia without CC/MCC
    974HIV with Major Related Condition with MCC
    975HIV with Major Related Condition with CC
    976HIV with Major Related Condition without CC/MCC

    Typical Clinical Scenarios

    • An adult previously healthy patient presents to the emergency department with acute onset multifocal neurologic deficits over days, including visual loss in one eye, unilateral weakness, and ataxia following a recent viral illness. MRI shows multiple demyelinating lesions disseminated in time and space but not meeting criteria for multiple sclerosis; clinicians diagnose an acute disseminated demyelinating event requiring urgent evaluation. Typical codes: G36.0, G36.9
    • A pediatric patient is admitted from clinic with rapidly progressive encephalopathy, altered level of consciousness, and diffuse MRI white matter changes after a febrile respiratory infection; care focuses on acute immunotherapy and supportive measures. The treating team documents an acute disseminated demyelinating process distinct from chronic demyelinating disorders and assigns an appropriate acute demyelination code. Typical codes: G36.1, G36.9
    • An adult with recent neurosurgical intervention develops new multifocal neurologic deficits and MRI-demonstrated diffuse demyelination; the condition is treated as a post-procedural or secondary acute demyelinating complication while other causes are excluded. The diagnosis code reflects an other acute disseminated demyelinating disorder as a complication/comorbidity during the hospitalization. Typical codes: G36.8, G36.9

    Related Codes

    G35-MULTIPLE-SCLEROSIS

    ICD-10-CM Code For Multiple Sclerosis: Group Overview

    G37-OTHER-DEMYELINATING-DISEASES

    ICD-10-CM Code For Other Demyelinating Diseases Of Central Nervous System: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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