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    v1.0.28
    OpenPayerBilling CodesInflammatory diseases of the central nervous systemICD-10-CM g05-encephalitis-myelitis-encephalomyelitis
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    ICD-10-CM Code For Encephalitis Myelitis And Encephalomyelitis In Diseases Classified Elsewhere: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group G05 includes inflammatory diseases of the central nervous system occurring in the context of other systemic or infectious conditions, such as encephalitis, myelitis, and encephalomyelitis associated with specified diseases. These ICD-10-CM diagnosis codes are used to document clinical scenarios involving central nervous system inflammation related to underlying diseases, capturing organ involvement and clinical complexity such as extent of neurologic deficits and etiologic associations. Accurate coding within the ICD-10-CM G05 group supports proper claim adjudication / complete clinical documentation / appropriate reimbursement.

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    ICD-10-CM G05: Encephalitis, Myelitis And Encephalomyelitis In Diseases Classified Elsewhere Overview

    This group represents inflammatory diseases of the central nervous system that occur as manifestations of other underlying systemic or infectious diseases, including encephalitis, myelitis, and encephalomyelitis. These conditions affect the brain, spinal cord, or both and can produce focal neurologic deficits, altered mental status, and other serious complications. Accurate coding matters for appropriate claim adjudication and to reflect clinical complexity that influences reimbursement.

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    When to Use

    Assign a code from this group when a patient has documented encephalitis, myelitis, or encephalomyelitis that is explicitly linked to another diagnosed disease. Use these codes to reflect cases where the central nervous system inflammation is secondary to or a complication of a separately classified condition.

    ICD-10-CM Codes

    2 rows

    ICD-10-CM CodeDescription
    G05.3Encephalitis and encephalomyelitis in diseases classified elsewhere
    G05.4Myelitis in diseases classified elsewhere

    DRG Codes

    5 rows

    DRG CodeDescription
    023Craniotomy with Major Device Implant or Acute Complex CNS Principal Diagnosis with MCC or Antineoplastic Implant or Epilepsy with Neurostimulator
    024Craniotomy with Major Device Implant or Acute Complex CNS Principal Diagnosis without MCC
    097Non-Bacterial Infection of Nervous System Except Viral Meningitis with MCC
    098Non-Bacterial Infection of Nervous System Except Viral Meningitis with CC
    099Non-Bacterial Infection of Nervous System Except Viral Meningitis without CC/MCC

    Typical Clinical Scenarios

    • An adult presents to the emergency department with acute onset fever, severe headache, confusion, and new focal neurological deficits after recent systemic infection; MRI shows brain parenchymal inflammation and CSF demonstrates lymphocytic pleocytosis. The acute, inflammatory central nervous system involvement attributable to an underlying systemic infectious or inflammatory disease leads to assignment of a code from this group for encephalitis in disease classified elsewhere. Typical codes: G05.3
    • A patient with a known systemic autoimmune connective tissue disease develops subacute progressive lower limb weakness, sensory level, and bladder dysfunction over days to weeks; spinal MRI demonstrates longitudinal inflammatory lesions consistent with myelitis related to the underlying systemic disorder. Because the myelitis is caused by and coded with the other systemic disease, a code from this group is used to capture myelitis in diseases classified elsewhere. Typical codes: G05.4
    • An inpatient with an established systemic vasculitis is hospitalized for worsening neurologic status characterized by both encephalopathic features and spinal cord dysfunction after discontinuation of immunosuppression; evaluation attributes the CNS inflammation to the underlying vasculitic process rather than a primary CNS disease. When encephalomyelitis manifestations are recorded as resulting from the systemic disease, a code from this group is assigned to denote CNS inflammation in disease classified elsewhere. Typical codes: G05.3, G05.4

    Related Codes

    G00-BACTERIAL-MENINGITIS-NOT-ELSEWHERE-CLASSIFIED

    ICD-10-CM Code For Bacterial Meningitis Not Elsewhere Classified: Group Overview

    G01-MENINGITIS-IN-BACTERIAL-DISEASES

    ICD-10-CM Code For Meningitis In Bacterial Diseases Classified Elsewhere: Group Overview

    G02-MENINGITIS-DUE-TO-OTHER-INFECTIONS

    ICD-10-CM Code For Meningitis In Other Infectious And Parasitic Diseases Classified Elsewhere: Group Overview

    G03-MENINGITIS-DUE-TO-OTHER-CAUSES

    ICD-10-CM Code For Meningitis Due To Other And Unspecified Causes: Group Overview

    G04-ENCEPHALITIS-MYELITIS-ENCEPHALOMYELITIS

    ICD-10-CM Code For Encephalitis, Myelitis And Encephalomyelitis: Group Overview

    G06-INTRACRANIAL-AND-INTRASPINAL-ABSCESS

    ICD-10-CM Code For Intracranial And Intraspinal Abscess And Granuloma: Group Overview

    G07-INTRACRANIAL-AND-INTRASPINAL-ABSCESS

    ICD-10-CM Code For Intracranial And Intraspinal Abscess And Granuloma In Diseases Classified Elsewhere: Group Overview

    G08-INTRACRANIAL-AND-INTRASPINAL-PHLEBITIS

    ICD-10-CM Code For Intracranial And Intraspinal Phlebitis And Thrombophlebitis: Group Overview

    G09-SEQUELAE-OF-CENTRAL-NERVOUS-SYSTEM-INFLAMMATION

    ICD-10-CM Code For Sequelae Of Inflammatory Diseases Of Central Nervous System: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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