CPT code 87538 describes a laboratory test that uses an amplified probe technique to provide a definitive diagnosis of HIV‑2 from a patient specimen; this is a molecular diagnostic service typically performed in a clinical laboratory or hospital laboratory setting and reported when amplification-based probe detection is used to identify HIV‑2 infection.

For related coverage guidance, see recent payer policy updates: B-Hemolytic Streptococcus Testing, Human Immunodeficiency Virus (HIV) — Coverage Criteria for Testing and Resistance Assays, Hepatitis Testing (A, B, C, D) Coverage Criteria.