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    v1.0.28
    OpenPayerBilling CodesChemistry ProceduresCPT cpt-84315-non-urine-body-fluid-specific-gravity
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    CPT 84315: Specific Gravity Measurement of Non‑Urine Body Fluids

    CPT code 84315 describes laboratory measurement of specific gravity for specimens other than urine, indicating analysis of other body fluids (for example, cerebrospinal fluid or pleural fluid) to assess concentration or dilution. This service is a clinical laboratory test typically performed in a hospital or reference laboratory setting by a lab analyst using refractometry or other specific gravity measurement methods on non-urine bodily fluids.

    For related coverage guidance, see recent payer policy updates: Salivary Hormone Testing, Bone Turnover Markers Testing, Parathyroid Hormone, Phosphorus, Calcium, and Magnesium Testing.

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    Clinical & Coding Specifications

    Clinical Context

    A 56-year-old hospitalized patient with suspected pleural infection undergoes thoracentesis to obtain pleural fluid for diagnostic testing. The collected non-urine body fluid specimens—such as pleural, peritoneal, synovial, or cerebrospinal fluid—are routed to the laboratory. A clinical laboratory scientist or medical technologist performs specimen accessioning, documents appearance and volume, and measures specific gravity to help assess concentration and aid interpretation of other results (electrolytes, cell counts, chemistry, culture). Measurement is typically performed using a refractometer or appropriate laboratory instrument. Results are reported in the electronic medical record and used by the treating physician to support diagnoses such as dehydration, effusions, infection, or renal concentrating defects. Typical site of service is a hospital laboratory or independent clinical laboratory supporting inpatient wards, emergency departments, or outpatient clinics; the service type is clinical laboratory testing for non-urine body fluids under physician or laboratory director oversight.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    36415Collection of venous blood by venipunctureBlood tests often performed concurrently with fluid analysis to correlate chemistry and infection markers
    88305Level IV surgical pathology, gross and microscopic examinationIf fluid cytology requires microscopic pathologic evaluation following cell concentration
    87070Culture, bacterial; aerobic, with isolation and presumptive identificationPerformed when fluid infection is suspected; often ordered alongside specific gravity and chemistry
    83010Hemoglobin; glycated (A1c)Example laboratory test ordered in parallel for systemic evaluation though not specific to fluid analysis
    99000Handling and/or conveyance of specimen for transfer to another facilityWhen specimens are sent to a reference lab for specialized testing

    Related Modifiers

    5 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    90Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    275N00000XMedicare Defined Swing Bed Hospital UnitA unit of a hospital that has a Medicare provider agreement and has been granted approval from HCFA to provide post-hospital extended care services an…
    207QB0505XDiabetology (Internal Medicine) PhysicianAn internist who specializes in diagnosis and management of type 1, type 2, gestational, and atypical diabetes; diabetes complications; hospital manag…
    163WE0003XEmergency Registered NurseNursing Service Providers · Registered Nurse
    111NP0017XPediatric ChiropractorThe Pediatric Chiropractor is a chiropractor with specialized, advanced training and certification in the evaluation, care and management of health an…
    2086P0122XPhysician Nutrition Specialist (Surgery)A physician who specializes in the diagnosis and treatment of primary nutritional diseases (e.g., undernutrition, overnutrition, and genetic or acquir…
    332800000XIndian Health Service/Tribal/Urban Indian Health (I/T/U) PharmacyAn Indian Health Service/Tribal/Urban Indian Health (I/T/U) Pharmacy means a pharmacy operated by the Indian Health Service, an Indian tribe or tribal…
    136A00000XRegistered Dietetic TechnicianA Dietetic Technician, Registered (DTR)/Nutrition and Dietetics Technician, Registered (NDTR) is an individual holding a nationally protected title is…
    207PE0005XUndersea and Hyperbaric Medicine (Emergency Medicine) PhysicianA specialist who treats decompression illness and diving accident cases and uses hyperbaric oxygen therapy to treat such conditions as carbon monoxide…

    Related ICD-10-CM Codes

    28 rows

    ICD-10-CM CodeDescription
    E10.9Type 1 diabetes mellitus without complications
    E11.9Type 2 diabetes mellitus without complications
    E86.0Dehydration
    E86.1Hypovolemia
    I10Essential (primary) hypertension
    I50.9Heart failure, unspecified
    J96.00Acute respiratory failure, unspecified whether with hypoxia or hypercapnia
    K57.20Diverticulitis of large intestine with perforation and abscess without bleeding
    K57.80Diverticulitis of intestine, part unspecified, with perforation and abscess without bleeding
    K65.0Generalized (acute) peritonitis

    Showing 1–10 of 28

    Related Payer Policy Updates

    Specialty: Endocrinology1 / 3

    5 rows

    PolicyPayerEffective Date
    Salivary Hormone TestingOscar Health2026-10-01
    Bone Turnover Markers TestingOscar Health2026-10-01
    Parathyroid Hormone, Phosphorus, Calcium, and Magnesium TestingOscar Health2026-10-01
    Testosterone — Coverage Criteria for Measurement and MonitoringOscar Health2026-10-01
    Thyroid Disease TestingOscar Health2026-10-01

    Related Codes

    CPT-82009-KETONE-BODIES-QUALITATIVE-TEST

    CPT 82009: Qualitative Ketone Bodies Test

    CPT-82010-QUANTITATIVE-KETONE-BODIES-ASSAY-SERUM-PLASMA

    CPT 82010: Quantitative Ketone Bodies in Serum or Plasma

    CPT-82013-ACETYLCHOLINESTERASE-QUANTITATIVE-ASSAY

    CPT 82013: Quantitative Acetylcholinesterase (Acetylhydrolase) Assay

    CPT-82016-QUALITATIVE-ACYLCARNITINES-METABOLIC-SCREEN

    CPT 82016: Qualitative Acylcarnitines, Plasma/Serum/Urine

    CPT-82017-QUANTITATIVE-ACYLCARNITINE-ANALYSIS

    CPT 82017: Quantitative Acylcarnitine Analysis

    CPT-82024-QUANTITATIVE-CORTICOTROPIN-ACTH-ASSAY

    CPT 82024: Adrenocorticotropic Hormone (ACTH) Quantitative Assay

    CPT-82030-QUANTITATIVE-CAMP-PLASMA-URINE-ASSAY

    CPT 82030: Quantitative cyclic AMP assay on plasma or urine

    CPT-82040-QUANTITATIVE-ALBUMIN-MEASUREMENT

    CPT 82040: Quantitative Albumin Measurement

    CPT-82042-QUANTITATIVE-ALBUMIN-NONBLOOD-FLUID

    CPT 82042: Albumin Quantitation in Non-Blood Body Fluid

    CPT-82043-URINE-ALBUMIN-QUANTITATION-KIDNEY-DISEASE

    CPT 82043: Urine Albumin Quantitative Assay

    Showing 1–10 of 411

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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