Summary & Overview
CPT 84060: Total Acid Phosphatase Measurement, Serum
CPT code 84060 denotes measurement of total acid phosphatase activity, a clinical chemistry laboratory test performed most often on serum to evaluate enzyme levels produced by the liver, bone, spleen, kidneys and, in males, the prostate. The assay can provide diagnostic or monitoring information for hepatobiliary, bone, renal, and prostate-related conditions, and remains relevant where acid phosphatase measurement contributes to clinical decision-making.
Key payers covered in this national overview include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find concise context on clinical use, expected service setting, and where this code fits within laboratory service lines. The publication also outlines common modifiers associated with laboratory services and notes which data elements were unavailable in the input.
This summary is intended to orient billing and clinical staff to the clinical purpose and typical site of service for CPT code 84060, and to preview the benchmarks and policy-oriented details that follow in the full publication, including utilization context, payer considerations, and coding practice notes.
Billing Code Overview
CPT code 84060 reports a laboratory measurement of total acid phosphatase, an enzyme produced primarily by the liver, bone, spleen, kidneys, and in males the prostate. The test is most commonly performed on a serum specimen to quantify enzyme activity.
Service Type: Laboratory test — clinical chemistry
Typical Site of Service: Clinical laboratory or hospital laboratory (serum specimen collection and analysis)
Clinical & Coding Specifications
Clinical Context
A 68-year-old male with a history of prostate cancer presents for routine oncologic surveillance. His oncologist orders a serum total acid phosphatase to evaluate for potential prostate disease activity and to assess for other causes of elevated acid phosphatase such as hepatic or bone pathology. A phlebotomist draws a serum specimen in an outpatient laboratory or hospital outpatient phlebotomy station. The specimen is processed by the clinical laboratory; the lab analyst performs a quantitative enzymatic assay to measure total acid phosphatase activity. Results are reported to the ordering provider and placed in the electronic medical record for comparison with prior values. Typical sites of service include hospital outpatient laboratory, independent clinical laboratory, ambulatory surgery center laboratory, and physician office-based laboratory services.
Coding Specifications
| Modifier | Description | When to Use |
|---|---|---|
00 | No modifier / default | Use when no specific modifier applies for the laboratory service |
26 | Professional component | Use when reporting only the professional interpretation or consultation portion, if applicable for tests with interpretation component |