CPT 83992: Phencyclidine (PCP) Level Assay

CPT code 83992 describes a laboratory assay for measuring phencyclidine (PCP) levels in a biological specimen, typically a urine or blood sample; the service is a toxicology/drug quantification performed in clinical laboratories, hospital labs, or outpatient diagnostic settings to identify and quantify this potent illicit drug of abuse.

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CPT 83992: Phencyclidine (PCP) Level Assay

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Clinical & Coding Specifications

Clinical Context

A 24-year-old adult presents to the emergency department after being found confused and agitated by bystanders following a party. The emergency clinician orders toxicology screening because of suspected illicit drug intoxication and altered mental status. A urine specimen is collected and sent to the hospital laboratory for qualitative and/or quantitative drug testing. The lab analyst performs an assay for phencyclidine (PCP) levels using immunoassay screening and, if needed, confirmatory testing such as gas chromatography–mass spectrometry (GC-MS) or liquid chromatography–tandem mass spectrometry (LC-MS/MS) to measure PCP concentration. The measured level assists the clinical team in confirming exposure, assessing severity, and informing monitoring and disposition decisions. Typical workflow steps include specimen accessioning, specimen preparation, analytic measurement, result verification, and reporting to the ordering clinician. This testing is commonly ordered in emergency departments, inpatient hospitals, urgent care centers, and forensic or occupational settings when PCP exposure is suspected.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`83992`	Phencyclidine (PCP) assay; qualitative or quantitative	Primary code describing measurement of PCP in biological specimens.
`80305`	Drug test, presumptive, any number of drug classes; initial screen (e.g., immunoassay)	Commonly performed as an initial screening test before specific PCP confirmation.
`80306`	Drug test, presumptive, each additional drug class	Used when additional screening drug classes are added to the panel alongside PCP.
`80307`	Drug test, presumptive, definitive confirmation (e.g., GC-MS)	Used for confirmatory testing of PCP when screening is positive or quantification is required.
`82570`	Assay of ethanol (blood)	May be ordered concurrently when assessing acute intoxication with PCP to evaluate co-ingestion.

Related Modifiers

5 rows

Modifier	Description	When to Use
26	Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…	- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
59	Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…	- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
90	Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…	- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…
91	Modifier 91 — “Repeat Clinical Diagnostic Laboratory Test” — is appended when the exact same CPT laboratory test is performed more than once for the same patient on the same day because serial,…	- Use modifier 91 when the exact same CPT laboratory test is performed more than once on the same patient on the same date because serial or repeated testing is medically necessary to monitor…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
207RC0000X	Cardiovascular Disease Physician	An internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions such as heart attacks and life-threaten…
207RP1001X	Pulmonary Disease Physician	An internist who treats diseases of the lungs and airways. The pulmonologist diagnoses and treats cancer, pneumonia, pleurisy, asthma, occupational an…
207L00000X	Anesthesiology Physician	An anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
208D00000X	General Practice Physician	A physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
133VN1501X	Sports Dietetics Nutrition Registered Dietitian	An individual who is a Board Certified Specialist in Sports Dietetics and applies evidence-based nutrition knowledge in exercise and sports. RDNs spec…
261QG0250X	Genetics Clinic/Center	An entity, facility, or distinct part of a facility providing analysis of family history, genetic laboratory testing and analysis, diagnosis of geneti…
252Y00000X	Early Intervention Provider Agency	Early intervention services are an effective way to address the needs of infants and toddlers who have developmental delays or disabilities. The servi…
106S00000X	Behavior Technician	The behavior technician is a paraprofessional who practices under the close, ongoing supervision of a behavior analyst or assistant behavior analyst c…

Related Codes

CPT-80320-ALCOHOL-DETECTION-IN-SPECIMEN

CPT 80320: Alcohol Detection and Quantification

CPT-80321-ALCOHOL-BIOMARKER-ASSAY

CPT 80321: Alcohol Biomarker Assay, One or Two Compounds

CPT-80322-ALCOHOL-BIOMARKER-PANEL-MULTI-ANALYTE

CPT 80322: Alcohol Biomarker Panel, Three or More Compounds

CPT-80323-ALKALOID-DRUG-LEVEL-ANALYSIS

CPT 80323: Alkaloid Drug Identification and Quantitation

CPT-80324-AMPHETAMINE-DRUG-TESTING-LAB-ASSAY

CPT 80324: Amphetamine Detection and Quantification

CPT-80325-AMPHETAMINES-DETECTION-AND-QUANTIFICATION

CPT 80325: Detection of Three or Four Amphetamines

CPT-80326-AMPHETAMINES-PANEL-5-OR-MORE

CPT 80326: Detection/Quantification of Five or More Amphetamines

CPT-80334-SEROTONERGIC-ANTIDEPRESSANT-PANEL

CPT 80334: Detection of Six or More Serotonergic Antidepressants

CPT-80335-TRICYCLIC-ANTIDEPRESSANT-ASSAY

CPT 80335: Tricyclic and Cyclical Antidepressant Assay

CPT-80344-MULTI-ANTIPSYCHOTIC-PANEL-SEVEN-PLUS-DRUGS

CPT 80344: Multiplex Antipsychotic Drug Detection (7+ agents)

Showing 1–10 of 24

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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Clinical & Coding Specifications

Clinical Context

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`83992`	Phencyclidine (PCP) assay; qualitative or quantitative	Primary code describing measurement of PCP in biological specimens.
`80305`	Drug test, presumptive, any number of drug classes; initial screen (e.g., immunoassay)	Commonly performed as an initial screening test before specific PCP confirmation.
`80306`	Drug test, presumptive, each additional drug class	Used when additional screening drug classes are added to the panel alongside PCP.
`80307`	Drug test, presumptive, definitive confirmation (e.g., GC-MS)	Used for confirmatory testing of PCP when screening is positive or quantification is required.
`82570`	Assay of ethanol (blood)	May be ordered concurrently when assessing acute intoxication with PCP to evaluate co-ingestion.

Related Modifiers

5 rows

Modifier	Description	When to Use
26	Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…	- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
59	Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…	- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
90	Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…	- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…
91	Modifier 91 — “Repeat Clinical Diagnostic Laboratory Test” — is appended when the exact same CPT laboratory test is performed more than once for the same patient on the same day because serial,…	- Use modifier 91 when the exact same CPT laboratory test is performed more than once on the same patient on the same date because serial or repeated testing is medically necessary to monitor…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
207RC0000X	Cardiovascular Disease Physician	An internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions such as heart attacks and life-threaten…
207RP1001X	Pulmonary Disease Physician	An internist who treats diseases of the lungs and airways. The pulmonologist diagnoses and treats cancer, pneumonia, pleurisy, asthma, occupational an…
207L00000X	Anesthesiology Physician	An anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
208D00000X	General Practice Physician	A physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
133VN1501X	Sports Dietetics Nutrition Registered Dietitian	An individual who is a Board Certified Specialist in Sports Dietetics and applies evidence-based nutrition knowledge in exercise and sports. RDNs spec…
261QG0250X	Genetics Clinic/Center	An entity, facility, or distinct part of a facility providing analysis of family history, genetic laboratory testing and analysis, diagnosis of geneti…
252Y00000X	Early Intervention Provider Agency	Early intervention services are an effective way to address the needs of infants and toddlers who have developmental delays or disabilities. The servi…
106S00000X	Behavior Technician	The behavior technician is a paraprofessional who practices under the close, ongoing supervision of a behavior analyst or assistant behavior analyst c…

Related Codes

CPT-80320-ALCOHOL-DETECTION-IN-SPECIMEN

CPT 80320: Alcohol Detection and Quantification

CPT-80321-ALCOHOL-BIOMARKER-ASSAY

CPT 80321: Alcohol Biomarker Assay, One or Two Compounds

CPT-80322-ALCOHOL-BIOMARKER-PANEL-MULTI-ANALYTE

CPT 80322: Alcohol Biomarker Panel, Three or More Compounds

CPT-80323-ALKALOID-DRUG-LEVEL-ANALYSIS

CPT 80323: Alkaloid Drug Identification and Quantitation

CPT-80324-AMPHETAMINE-DRUG-TESTING-LAB-ASSAY

CPT 80324: Amphetamine Detection and Quantification

CPT-80325-AMPHETAMINES-DETECTION-AND-QUANTIFICATION

CPT 80325: Detection of Three or Four Amphetamines

CPT-80326-AMPHETAMINES-PANEL-5-OR-MORE

CPT 80326: Detection/Quantification of Five or More Amphetamines

CPT-80334-SEROTONERGIC-ANTIDEPRESSANT-PANEL

CPT 80334: Detection of Six or More Serotonergic Antidepressants

CPT-80335-TRICYCLIC-ANTIDEPRESSANT-ASSAY

CPT 80335: Tricyclic and Cyclical Antidepressant Assay

CPT-80344-MULTI-ANTIPSYCHOTIC-PANEL-SEVEN-PLUS-DRUGS

CPT 80344: Multiplex Antipsychotic Drug Detection (7+ agents)

Showing 1–10 of 24

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

CPT 83992: Phencyclidine (PCP) Level Assay

Sign up for cpt 83992 policy alerts

CPT 83992: Phencyclidine (PCP) Level Assay

Sign up for cpt 83992 policy alerts

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

What does CPT 83992 represent and what specimens are commonly tested?

Which billing modifiers are applicable to CPT 83992?

What other CPT codes are often billed with or related to 83992?

In what clinical settings and situations is CPT 83992 typically ordered?

Which payers cover this test and are specific reimbursement rates provided?

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

What does CPT 83992 represent and what specimens are commonly tested?

Which billing modifiers are applicable to CPT 83992?

What other CPT codes are often billed with or related to 83992?

In what clinical settings and situations is CPT 83992 typically ordered?

Which payers cover this test and are specific reimbursement rates provided?

References