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    v1.0.30
    OpenPayerBilling CodesTherapeutic Nuclear Medicine ProceduresCPT cpt-79445-transarterial-radioembolization-intra-arterial-radioactive-injection
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    CPT 79445: Transarterial Radioembolization (Intra-arterial Embolization)

    Medicare pays $109 on average nationally for this procedure.

    CPT code 79445 describes a transarterial radioembolization procedure in which a provider injects a liquid containing radioactive particles into the artery supplying blood to a tumor to occlude tumor blood supply; service type: image-guided intra-arterial embolization with radiotherapeutic microspheres; typical site of service: hospital interventional radiology suite or specialized outpatient interventional center.

    For related coverage guidance, see recent payer policy updates: Vafseo (vadadustat) for anemia in CKD on dialysis, Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family Plans, Kerendia (finerenone) — Coverage Criteria.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 64-year-old patient with hepatocellular carcinoma localized to the right hepatic lobe is referred for transarterial radioembolization. The interventional radiology team performs pre-procedure angiography and mapping to identify hepatic arterial anatomy and extrahepatic branches, followed by administration of technetium-99m macroaggregated albumin for lung shunt fraction assessment. On the treatment day, under moderate sedation in an angiography suite, the operator gains femoral or radial arterial access, selectively catheterizes the right hepatic artery, and injects radioactive microspheres to deliver locoregional radiation and embolize tumor microvasculature. Post-procedure monitoring includes vital signs, assessment for access site complications, pain control, and outpatient follow-up with cross-sectional imaging and oncology for response assessment and systemic therapy coordination.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    36245Selective catheter placement, cerebral, upper extremity, neck, or visceral vessels when performed for diagnostic or therapeutic purposesUsed for selective catheterization of hepatic arterial branches during mapping or treatment
    36246Selective catheter placement, radiological supervision and interpretationUsed when selective catheter placement of visceral vessels is performed as part of embolization
    37243Vascular embolization or occlusion, inclusive of all radiological supervision and interpretation; for tumors (eg, chemoembolization, radioembolization)Closely related code for transcatheter embolization procedures directed at tumor vasculature
    78830Tumor imaging, arterial, for localization and evaluation (e.g., hepatic arterial technetium-99m MAA localization studies)Used in pre-procedure planning to assess particle distribution and lung shunt fraction
    76937Ultrasound guidance for vascular access (e.g., needle guidance)Used when ultrasound is used for vascular access prior to angiography

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    81Modifier -81 indicates a physician served as a minimal assistant surgeon for part—not all—of an operative procedure. Use when a physician’s assisting role is limited and does not represent full…- Use CPT modifier -81 when a physician acts as a minimum assistant surgeon who assists during only part (a limited portion) of an operative procedure; append -81 to the primary surgical CPT code to…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RC0000X
    208D00000X
    2084P0800X
    363L00000X
    1835E0208X
    1744R1102X
    332900000X
    2471C3402X

    Related ICD-10-CM Codes

    25 rows

    ICD-10-CM CodeDescription
    C18.7Malignant neoplasm of sigmoid colon
    C18.9Malignant neoplasm of colon, unspecified
    C20Malignant neoplasm of rectum
    C21.8Malignant neoplasm of overlapping sites of rectum, anus and anal canal
    C22.0Liver cell carcinoma
    C22.7Other specified carcinomas of liver
    C22.8Malignant neoplasm of liver, primary, unspecified as to type
    C22.9Malignant neoplasm of liver, not specified as primary or secondary
    C24.0Malignant neoplasm of extrahepatic bile duct
    C25.9Malignant neoplasm of pancreas, unspecified

    Showing 1–10 of 25

    Related Payer Policy Updates

    Specialty: Nephrology1 / 2

    10 rows

    PolicyPayerEffective Date
    Vafseo (vadadustat) for anemia in CKD on dialysisCigna2026-08-15
    Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family PlansCigna2026-08-15
    Kerendia (finerenone) — Coverage CriteriaBlue Cross Blue Shield - Iowa2026-08-05
    Voyxact (sibeprenlimab-szsl) — Prior authorization / medical necessity for primary IgA nephropathyColorado Rocky Mountain Health Plans2026-08-01
    Oxlumo (lumasiran) and Rivfloza (nedosiran) — Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Korsuva (difelikefalin) — Medical Benefit Drug Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Complement Inhibitors - EmpaveliCigna2026-08-01
    Tolvaptan (Jynarque)Cigna2026-08-01
    Nephrology - Filspari (sparsentan) coverageCigna2026-08-01
    Rivfloza (nedosiran) prior authorization for PH1UnitedHealthcare2026-08-01

    Related Codes

    CPT-79005-ORAL-RADIOPHARMACEUTICAL-THERAPY

    CPT 79005: Oral Radiopharmaceutical Therapy

    CPT-79101-RADIOPHARMACEUTICAL-INTRAVENOUS-THERAPY

    CPT 79101: Intravenous Radiopharmaceutical Therapy

    CPT-79200-INTRACAVITARY-RADIOPHARMACEUTICAL-ADMINISTRATION

    CPT 79200: Intracavitary Radiopharmaceutical Administration

    CPT-79300-INTERSTITIAL-BRACHYTHERAPY-IMPLANTATION

    CPT 79300: Brachytherapy Radioactive Seed/Wire Implantation

    CPT-79403-RADIOLABELED-MONOCLONAL-ANTIBODY-INFUSION

    CPT 79403: Intravenous Radiolabeled Monoclonal Antibody Infusion

    CPT-79440-RADIOPHARMACEUTICAL-INJECTION-FOR-SYNOVIAL-INFLAMMATION

    CPT 79440: Therapeutic Radioactive Joint Injection

    CPT-79999-RADIOPHARMACEUTICAL-THERAPY-UNLISTED-PROCEDURE

    CPT 79999: Radiopharmaceutical Therapy, Unlisted Procedure

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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