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    OpenPayerBilling CodesUltrasonic Guidance ProceduresCPT cpt-76945-ultrasound-guidance-chorionic-villus-sampling-supervision
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    CPT 76945: Ultrasound Supervision and Interpretation for Chorionic Villus Sampling

    Medicare pays $33 on average nationally for this procedure.

    CPT code 76945 describes ultrasound supervision and real-time imaging interpretation provided during a separately reportable chorionic villus sampling procedure, a diagnostic imaging guidance service performed to localize placental tissue for transabdominal or transcervical sampling; service type: ultrasound guidance with imaging supervision and interpretation; typical site of service: outpatient imaging suite, ambulatory surgery center, or hospital outpatient department where prenatal diagnostic procedures are performed.

    For related coverage guidance, see recent payer policy updates: Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillation, Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillation, Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillation.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 34-year-old pregnant patient at 10 weeks' gestation is referred for chorionic villus sampling (CVS) after a positive first-trimester screening indicating increased risk for a chromosomal abnormality. The maternal-fetal medicine specialist schedules the CVS in an outpatient ambulatory surgery or procedure suite. Before the procedure, the patient undergoes pre-procedure counseling and informed consent. On the day of service, an ultrasound is used to locate the placenta and guide transabdominal or transcervical sampling of chorionic villi. The supervising physician performs real-time imaging supervision and interprets the ultrasound to ensure needle trajectory avoids fetal parts and major maternal vessels; images are documented and saved. The proceduralist separately reports the tissue sampling service; 76945 is reported by the imaging physician for supervision and interpretation of the ultrasound guidance for the separately reportable CVS sampling. Typical billing includes facility and professional components as applicable, with potential application of modifiers for reduced services, multiple physicians, or technical/professional splits. Typical sites of service are outpatient ambulatory surgery centers, hospital outpatient departments, or specialized maternal-fetal medicine clinics equipped for invasive prenatal procedures.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    59015Chorionic villus sampling (separate procedure)This is the tissue sampling procedure performed by the proceduralist; 76945 represents the imaging supervision and interpretation that guides this separately reportable sampling.
    76815Transvaginal ultrasound, pregnant uterus, real-time with image documentation, first trimesterMay be performed to localize the fetus and placenta prior to or during transcervical CVS guidance; provides diagnostic images complementary to 76945.
    76816Transabdominal ultrasound, pregnant uterus, real-time with image documentation, real time for first trimesterMay be used when transabdominal approach is chosen for ultrasound guidance during CVS.
    36556Collection of blood from umbilical cord (fetal blood sampling)Performed in different scenarios; listed as related invasive fetal sampling procedures that may require similar ultrasound guidance workflows.
    76933Ultrasound guidance for vascular access requiring imaging supervision and interpretationConceptually related as an ultrasound guidance code category; illustrates how 76945 is used specifically for CVS guidance rather than vascular access.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207Q00000X
    207RP1001X
    367500000X
    385H00000X
    235Z00000X
    246ZG1000X
    2279P3900X
    171WV0202X

    Related ICD-10-CM Codes

    20 rows

    ICD-10-CM CodeDescription
    O09.511Supervision of elderly primigravida, first trimester
    O09.512Supervision of elderly primigravida, second trimester
    O09.513Supervision of elderly primigravida, third trimester
    O09.521Supervision of elderly multigravida, first trimester
    O09.522Supervision of elderly multigravida, second trimester
    O09.523Supervision of elderly multigravida, third trimester
    O09.611Supervision of young primigravida, first trimester
    O09.612Supervision of young primigravida, second trimester
    O09.613Supervision of young primigravida, third trimester
    O20.0Threatened abortion

    Showing 1–10 of 20

    Related Payer Policy Updates

    Specialty: Cardiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillationpremerabluecrossofwashington2027-02-05
    Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillationpremerabluecrossofwashington2027-02-05
    Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillationpremerabluecrossofwashington2027-02-05
    Percutaneous Left Atrial Appendage Closure - Medical PolicyHealth-New-England2027-02-01
    Transcatheter Mitral Valve Repair Medical PolicyHealth-New-England2027-02-01
    Cardiac Electrophysiological (EP) Studies and Cardiac Ablation of Abnormal Electrical RhythmsCigna2027-01-15
    Biomarkers for Myocardial Infarction and Chronic Heart Failure Reimbursement PolicyHealthfirst2026-11-01
    Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillationpremerabluecrossofwashington2026-11-01
    Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillationpremerabluecrossofwashington2026-11-01
    Cardiology - TryvioCigna2026-11-01

    Related Codes

    CPT-76932-ULTRASOUND-GUIDANCE-ENDOMYOCARDIAL-BIOPSY-IMAGING-INTERPRETATION

    CPT 76932: Ultrasound-Guided Endomyocardial Biopsy Supervision and Interpretation

    CPT-76936-ULTRASOUND-GUIDED-PSEUDOANEURYSM-COMPRESSION-REPAIR

    CPT 76936: Ultrasound Guidance for Pseudoaneurysm/AV Fistula Compression

    CPT-76937-ULTRASOUND-GUIDANCE-VASCULAR-ACCESS

    CPT 76937: Ultrasound Guidance for Vascular Access

    CPT-76940-ULTRASOUND-GUIDANCE-PARENCHYMAL-ABLATION-MONITORING

    CPT 76940: Ultrasound Guidance for Parenchymal Tissue Ablation

    CPT-76941-ULTRASOUND-GUIDANCE-INTRAUTERINE-FETAL-TRANSFUSION-CORDOCENTESIS

    CPT 76941: Imaging Supervision for Intrauterine Fetal Transfusion/Cordocentesis

    CPT-76942-ULTRASOUND-GUIDANCE-NEEDLE-PLACEMENT

    CPT 76942: Ultrasound Guidance for Needle Placement

    CPT-76946-ULTRASOUND-GUIDANCE-AMNIOCENTESIS-SUPERVISION-INTERPRETATION

    CPT 76946: Ultrasound Guidance for Amniocentesis Supervision/Interpretation

    CPT-76948-ULTRASOUND-SUPERVISION-INTERPRETATION-OVA-ASPIRATION

    CPT 76948: Ultrasound Guidance for Ovum Aspiration

    CPT-76965-ULTRASOUND-GUIDED-INTERSTITIAL-BRACHYTHERAPY-PLACEMENT

    CPT 76965: Ultrasound-Guided Interstitial Radioelement Placement

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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