CPT 64483: Lumbar/Sacral Transforaminal Epidural Injection, Single Level

Medicare pays $275 and commercial payers pay $588 on average nationally for this procedure.

CPT code 64483 describes the injection of an anesthetic agent and/or steroid via a lumbar or sacral transforaminal epidural injection at a single spinal level; the service is a therapeutic interventional pain procedure typically performed in an ambulatory surgery center, hospital outpatient department, or office-based procedure suite using image guidance for needle placement.

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National Reimbursement Benchmarks

National averages position Medicare at a mean of $275.30 and BUCA (an average commercial benchmark) at $588.50, so BUCA’s mean is roughly $313.20 higher than Medicare, indicating materially higher commercial reimbursements for CPT 64483 versus the CMS average. Blue Cross Blue Shield’s mean ($810.30) and UnitedHealth Group’s mean ($348.20) bracket BUCA, while Aetna ($231.60) and Cigna ($298.30) sit closer to Medicare, illustrating a layered commercial market where some payers pay well above the Medicare baseline and others remain near it.

Dispersion measured by the interquartile range (P75 minus P25) highlights variation: Blue Cross Blue Shield is the widest with a spread of $!124100.00? Wait—must compute correctly. Compute P75-P25 for each: Aetna 300.2-92.4=207.8 -> $207.80; BCBS 1124.1-408.7=715.4 -> $715.40; BUCA 804.9-299.8=505.1 -> $505.10; Cigna 385.6-161.6=224.0 -> $224.00; UnitedHealth Group 452.0-209.5=242.5 -> $242.50; Medicare 286-255=31 -> $31.00. Blue Cross Blue Shield has the widest IQR at $715.40, while Medicare is the tightest at $31.00, with BUCA showing substantial commercial spread at $505.10.

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CPT 64483: Lumbar/Sacral Transforaminal Epidural Injection, Single Level

Medicare pays $275 and commercial payers pay $588 on average nationally for this procedure.

Customize your policy alerts

Sign up for cpt 64483 policy alerts

Get alerted when payer policies referencing 64483 are released or updated.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

National Reimbursement Benchmarks

National Payer Mean Reimbursement Rates

Clinical & Coding Specifications

Clinical Context

A 52-year-old patient with a several-month history of progressive right-sided lower back pain radiating into the posterior right thigh and calf, exacerbated by sitting and coughing, presents to a pain management clinic. Prior conservative care — physical therapy, oral analgesics including NSAIDs, and a short course of oral steroids — provided inadequate relief. Lumbar MRI demonstrates a right paracentral L4–L5 herniated nucleus pulposus with nerve root compression consistent with radiculopathy.

The clinical workflow begins with pre-procedure evaluation in the clinic: focused history and neurological exam, review of recent imaging, medication reconciliation (anticoagulant management per facility policy), informed consent documenting expected benefits and risks, and verification of the target spinal level. On the day of service the patient is brought to a procedure suite or fluoroscopy-equipped ambulatory surgical center. The procedure involves sterile preparation, local skin anesthesia, fluoroscopic guidance to the L4–L5 neural foramen, contrast confirmation of epidural/foraminal spread as indicated, and administration of a corticosteroid and/or local anesthetic via a transforaminal approach to a single lumbar level. Post-procedure monitoring occurs for vital signs and immediate complications before discharge with post-procedure instructions and follow-up planning.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`64484`	Injection(s), anesthetic agent and/or steroid, transforaminal epidural; lumbar or sacral, each additional level	Used when injections are performed at more than one lumbar or sacral level on the same date; billed in addition to the primary single-level code.
`62323`	Injection(s), of diagnostic or therapeutic substance(s), lumbar or sacral; with or without contrast	Alternative code for interlaminar or epidural injections differing in approach; may be used for non-transforaminal epidural injections.
`77003`	Fluoroscopic guidance and localization of needle or catheter tip for spine or paraspinous diagnostic or therapeutic injection procedures	Billed when fluoroscopic guidance is used to localize the needle tip during the transforaminal injection; often reported in conjunction per payer rules.
`20552`	Injection(s); single or multiple trigger point(s), 1 or 2 muscle(s)	Additional procedure that may be performed during the same visit for myofascial pain; reported separately if clinically distinct.

Related Modifiers

10 rows

Modifier	Description	When to Use
26	Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…	- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
50	Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…	- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
51	Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…	- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
59	Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…	- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
62	Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…	- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
76	Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…	- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
77	Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…	- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
79	Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…	- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
207L00000X	Anesthesiology Physician	An anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
208VP0000X	Pain Medicine Physician	Pain Medicine is a primary medical specialty based on a distinct body of knowledge and a well-defined scope of clinical practice that is founded on sc…
207XS0117X	Orthopaedic Surgery of the Spine Physician	Recognized by several state medical boards as a fellowship subspecialty program of orthopaedic surgery, orthopaedic surgeons of the spine deal with th…
164X00000X	Licensed Vocational Nurse	An individual with post-high school vocational training and practical experience in the provision of nursing care at a level less than that required f…
207WX0120X	Cornea and External Diseases Specialist Physician	An ophthalmologist who specializes in diseases of the cornea, sclera, eyelids, conjunctiva, and anterior segment of the eye.
2086S0122X	Plastic and Reconstructive Surgery Physician	A surgeon who specializes in plastic and reconstructive surgery.
261QL0400X	Lithotripsy Clinic/Center	Ambulatory Health Care Facilities · Clinic/Center
246ZE0600X	Electroneurodiagnostic Specialist/Technologist	Technologists, Technicians & Other Technical Service Providers · Specialist/Technologist, Other

Related Payer Policy Updates

Specialty: Anesthesiology1 / 3

10 rows

Policy	Payer	Effective Date
Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use Disorders	Premera Bluecross	2026-07-01
Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use Disorders	Premera Bluecross	2026-07-01
Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use Disorders	Premera Bluecross	2026-07-01
Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use Disorders	Premera Bluecross	2026-07-01
Elective Inpatient Services (for Idaho Only)	UnitedHealthcare	2026-06-01
Sites of Service	priority health	2026-06-01
Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Services	univerahealthcare	2026-05-21
Mm_0579_Coveragepositioncriteria_Anesthesia_Services_Selected_Nerve_Blocks	Cigna	2026-05-15
Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric Disorders	Blue Cross Blue Shield - North Carolina	2026-04-01
Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric Disorders	Blue Cross Blue Shield - North Carolina	2026-04-01

CPT 64400: Injection of Trigeminal Nerve Branch

CPT-64405-GREATER-OCCIPITAL-NERVE-INJECTION

CPT 64405: Greater Occipital Nerve Injection

CPT-64408-VAGUS-NERVE-INJECTION

CPT 64408: Vagus Nerve Injection (Vagal Nerve Block)

CPT-64415-BRACHIAL-PLEXUS-NERVE-BLOCK-INJECTION

CPT 64415: Brachial Plexus Injection for Regional Nerve Block

CPT-64416-BRACHIAL-PLEXUS-CONTINUOUS-INFUSION-CATHETER

CPT 64416: Brachial Plexus Continuous Catheter Infusion

CPT-64417-AXILLARY-NERVE-INJECTION-NERVE-BLOCK

CPT 64417: Axillary Nerve Injection for Regional Anesthesia or Steroid Delivery

CPT-64418-SUPRASCAPULAR-NERVE-INJECTION-SHOULDER

CPT 64418: Suprascapular Nerve Injection, Shoulder

CPT-64420-INTERCOSTAL-NERVE-INJECTION

CPT 64420: Intercostal Nerve Injection, Single Level

CPT-64421-INTERCOSTAL-NERVE-INJECTION-ADDITIONAL-LEVEL

CPT 64421: Intercostal Nerve Injection (Additional Level)

CPT-64425-ILIOINGUINAL-ILIOHYPOGASTRIC-NERVE-INJECTION

CPT 64425: Ilioinguinal/Iliohypogastric Nerve Injection

Showing 1–10 of 37

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

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Clinical & Coding Specifications

Clinical Context

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`64484`	Injection(s), anesthetic agent and/or steroid, transforaminal epidural; lumbar or sacral, each additional level	Used when injections are performed at more than one lumbar or sacral level on the same date; billed in addition to the primary single-level code.
`62323`	Injection(s), of diagnostic or therapeutic substance(s), lumbar or sacral; with or without contrast	Alternative code for interlaminar or epidural injections differing in approach; may be used for non-transforaminal epidural injections.
`77003`	Fluoroscopic guidance and localization of needle or catheter tip for spine or paraspinous diagnostic or therapeutic injection procedures	Billed when fluoroscopic guidance is used to localize the needle tip during the transforaminal injection; often reported in conjunction per payer rules.
`20552`	Injection(s); single or multiple trigger point(s), 1 or 2 muscle(s)	Additional procedure that may be performed during the same visit for myofascial pain; reported separately if clinically distinct.

Related Modifiers

10 rows

Modifier	Description	When to Use
26	Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…	- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
50	Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…	- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
51	Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…	- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
59	Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…	- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
62	Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…	- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
76	Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…	- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
77	Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…	- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
79	Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…	- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
207L00000X	Anesthesiology Physician	An anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
208VP0000X	Pain Medicine Physician	Pain Medicine is a primary medical specialty based on a distinct body of knowledge and a well-defined scope of clinical practice that is founded on sc…
207XS0117X	Orthopaedic Surgery of the Spine Physician	Recognized by several state medical boards as a fellowship subspecialty program of orthopaedic surgery, orthopaedic surgeons of the spine deal with th…
164X00000X	Licensed Vocational Nurse	An individual with post-high school vocational training and practical experience in the provision of nursing care at a level less than that required f…
207WX0120X	Cornea and External Diseases Specialist Physician	An ophthalmologist who specializes in diseases of the cornea, sclera, eyelids, conjunctiva, and anterior segment of the eye.
2086S0122X	Plastic and Reconstructive Surgery Physician	A surgeon who specializes in plastic and reconstructive surgery.
261QL0400X	Lithotripsy Clinic/Center	Ambulatory Health Care Facilities · Clinic/Center
246ZE0600X	Electroneurodiagnostic Specialist/Technologist	Technologists, Technicians & Other Technical Service Providers · Specialist/Technologist, Other

Related Payer Policy Updates

Specialty: Anesthesiology1 / 3

10 rows

Policy	Payer	Effective Date
Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use Disorders	Premera Bluecross	2026-07-01
Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use Disorders	Premera Bluecross	2026-07-01
Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use Disorders	Premera Bluecross	2026-07-01
Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use Disorders	Premera Bluecross	2026-07-01
Elective Inpatient Services (for Idaho Only)	UnitedHealthcare	2026-06-01
Sites of Service	priority health	2026-06-01
Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Services	univerahealthcare	2026-05-21
Mm_0579_Coveragepositioncriteria_Anesthesia_Services_Selected_Nerve_Blocks	Cigna	2026-05-15
Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric Disorders	Blue Cross Blue Shield - North Carolina	2026-04-01
Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric Disorders	Blue Cross Blue Shield - North Carolina	2026-04-01

CPT 64400: Injection of Trigeminal Nerve Branch

CPT-64405-GREATER-OCCIPITAL-NERVE-INJECTION

CPT 64405: Greater Occipital Nerve Injection

CPT-64408-VAGUS-NERVE-INJECTION

CPT 64408: Vagus Nerve Injection (Vagal Nerve Block)

CPT-64415-BRACHIAL-PLEXUS-NERVE-BLOCK-INJECTION

CPT 64415: Brachial Plexus Injection for Regional Nerve Block

CPT-64416-BRACHIAL-PLEXUS-CONTINUOUS-INFUSION-CATHETER

CPT 64416: Brachial Plexus Continuous Catheter Infusion

CPT-64417-AXILLARY-NERVE-INJECTION-NERVE-BLOCK

CPT 64417: Axillary Nerve Injection for Regional Anesthesia or Steroid Delivery

CPT-64418-SUPRASCAPULAR-NERVE-INJECTION-SHOULDER

CPT 64418: Suprascapular Nerve Injection, Shoulder

CPT-64420-INTERCOSTAL-NERVE-INJECTION

CPT 64420: Intercostal Nerve Injection, Single Level

CPT-64421-INTERCOSTAL-NERVE-INJECTION-ADDITIONAL-LEVEL

CPT 64421: Intercostal Nerve Injection (Additional Level)

CPT-64425-ILIOINGUINAL-ILIOHYPOGASTRIC-NERVE-INJECTION

CPT 64425: Ilioinguinal/Iliohypogastric Nerve Injection

Showing 1–10 of 37

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

OpenPayer

CPT 64483: Lumbar/Sacral Transforaminal Epidural Injection, Single Level

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National Reimbursement Benchmarks

OpenPayer

CPT 64483: Lumbar/Sacral Transforaminal Epidural Injection, Single Level

Sign up for cpt 64483 policy alerts

National Reimbursement Benchmarks

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Payer Policy Updates

Related Codes

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Payer Policy Updates

Related Codes

References

CPT 64483: Lumbar/Sacral Transforaminal Epidural Injection, Single Level

Sign up for cpt 64483 policy alerts

National Reimbursement Benchmarks

CPT 64483: Lumbar/Sacral Transforaminal Epidural Injection, Single Level

Sign up for cpt 64483 policy alerts

National Reimbursement Benchmarks

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Payer Policy Updates

Related Codes

What clinical procedure does CPT 64483 describe and where is it typically performed?

Which diagnoses are commonly associated with billing CPT 64483?

Which claim modifiers are commonly used with CPT 64483 and when are they applied?

How do reimbursement rates for CPT 64483 compare across payers and to Medicare?

What related CPT codes should be considered when billing for a transforaminal injection using CPT 64483?

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Payer Policy Updates

Related Codes

What clinical procedure does CPT 64483 describe and where is it typically performed?

Which diagnoses are commonly associated with billing CPT 64483?

Which claim modifiers are commonly used with CPT 64483 and when are they applied?

How do reimbursement rates for CPT 64483 compare across payers and to Medicare?

What related CPT codes should be considered when billing for a transforaminal injection using CPT 64483?

References