CPT code 64400 denotes injection of an anesthetic and/or steroid adjacent to a branch of the trigeminal (fifth cranial) nerve and is reported for each branch treated during a single procedure. This procedure is commonly used for diagnostic relief or therapeutic management of trigeminal neuralgia, facial pain, or related craniofacial pain syndromes. Nationally, proper coding of 64400 affects reimbursement, care pathways for facial pain management, and tracking of procedural utilization patterns.

Key payers addressed in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of clinical context, typical settings where the service is furnished, and what to expect in payer coverage considerations. The publication summarizes benchmark metrics and common billing practices, highlights relevant policy updates influencing authorization and coverage, and clarifies reporting expectations when multiple trigeminal branches are injected in one session.

Intended for practice managers, coders, and policy analysts, the content focuses on coding accuracy, billing implications when reporting per-branch injections, and the clinical scenarios in which 64400 is typically used. Data not available in the input is noted where applicable.