CPT code 64480 denotes a transforaminal epidural injection of an anesthetic and/or steroid in the cervical or thoracic spine for each additional level beyond the primary injection. This interventional pain management procedure is performed to deliver medication directly into the neural foramen to address radicular pain and inflammation. Its use has implications for clinical pathways, utilization oversight, and payer coverage policies across the country.

Key payers referenced in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. The publication provides a national view of how payers classify and reimburse this service, common billing practices, and the clinical context for using transforaminal injections in the cervical and thoracic regions.

Readers will find benchmarks for utilization and reimbursement practices where available, summaries of relevant policy considerations, and clinical context that clarifies when additional-level coding with 64480 is indicated. The report also identifies common modifiers used in practice and highlights areas where documentation and coding specificity affect coverage determinations. Data not available in the input is noted where applicable.