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    v1.0.30
    OpenPayerBilling CodesOther Procedures on the LiverCPT cpt-47399-unlisted-liver-procedure
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    CPT 47399: Unlisted Procedure, Liver

    CPT code 47399 is an unlisted procedure code used to report surgical or interventional procedures performed on the liver that do not have a specific CPT descriptor; it represents miscellaneous liver procedures performed in an operative or procedural setting such as the operating room or interventional suite and should be documented with a clear operative report describing the procedure, clinical indication, and extent of services.

    For related coverage guidance, see recent payer policy updates: Surgical Procedures, Outpatient Surgical Procedures - Site of Service, Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old patient with a history of chronic liver disease presents with a focal hepatic lesion identified on imaging that is atypical for common coded hepatic procedures. The interventional hepatobiliary surgeon performs a non-routine open or percutaneous operative procedure on the liver that does not have a specific CPT code, reported with 47399. Typical workflow includes pre-procedure imaging review (CT or MRI), informed consent highlighting the undefined-code nature of the operation, intraoperative ultrasound as needed, targeted resection, biopsy, ablation, or repair of hepatic tissue, and post-procedure monitoring for bleeding and liver function. The typical site of service is an inpatient operating room or an interventional radiology suite, with possible same-day or short inpatient observation depending on complexity and comorbidities. Documentation should describe the medical necessity, specific operative steps, duration, specimens obtained, and any complicating factors to support use of 47399.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    19301Partial hepatectomy; lobectomy or segmental resectionCommonly performed when hepatic lesion requires formal anatomic resection; may be coded instead of 47399 when applicable.

    | 47120 | Hepatectomy, wedge resection of liver | Used for nonanatomic wedge resections; may be performed in similar clinical scenarios and chosen when a specific code applies.

    | 47562 | Laparoscopy, surgical; cholecystectomy | May be performed before, during, or after hepatic procedures for biliary indications encountered intraoperatively.

    | 48999 | Unlisted procedure, pelvis | Example of analogous unlisted coding approach for other anatomic sites; demonstrates billing concept when no specific code exists (not a direct liver code).

    | 76942 | Ultrasonic guidance for needle placement | Frequently used adjunct for percutaneous liver biopsies or ablations to guide needle placement during the procedure.

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207T00000X
    208600000X
    207RA0000X
    364SG0600X
    246Q00000X
    224900000X
    251X00000X
    111NI0900X

    Related Payer Policy Updates

    Specialty: General Surgery1 / 3

    10 rows

    PolicyPayerEffective Date
    Surgical ProceduresUnitedHealthcare2026-09-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01

    Related Codes

    CPT-47380-OPEN-RADIOFREQUENCY-ABLATION-LIVER

    CPT 47380: Open Radiofrequency Ablation of Liver Tumor

    CPT-47381-OPEN-LIVER-CRYOABLATION

    CPT 47381: Open Cryosurgical Ablation of Liver Tumors

    CPT-47382-PERCUTANEOUS-RADIOFREQUENCY-ABLATION-LIVER-TUMOR

    CPT 47382: Percutaneous Radiofrequency Ablation of Liver Tumors

    CPT-47383-PERCUTANEOUS-LIVER-CRYOABLATION

    CPT 47383: Percutaneous Cryoablation of Liver Tumor(s)

    CPT-47384-IRREVERSIBLE-ELECTROPORATION-LIVER-TUMOR-ABLATION-PERCUTANEOUS

    CPT 47384: Percutaneous Irreversible Electroporation Ablation of Liver Tumor(s)

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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