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    v1.0.30
    OpenPayerBilling CodesOther Procedures on the LiverCPT cpt-47383-percutaneous-liver-cryoablation
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    CPT 47383: Percutaneous Cryoablation of Liver Tumor(s)

    Medicare pays $6094 on average nationally for this procedure.

    CPT code 47383 describes percutaneous cryoablation of one or more liver tumors, a image-guided minimally invasive tumor ablation procedure performed through the skin; service type: percutaneous cryosurgery/ablation; typical site of service: interventional radiology suite, outpatient surgical center, or hospital-based procedural unit.

    For related coverage guidance, see recent payer policy updates: Surgical Procedures, Outpatient Surgical Procedures - Site of Service, Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old patient with a history of colorectal cancer presents with one or more suspicious hepatic lesions on surveillance imaging. Cross-sectional imaging (contrast-enhanced CT or MRI) demonstrates one or two discrete liver metastases amenable to percutaneous ablation. The interventional radiology team schedules a percutaneous cryoablation of the liver tumors performed under conscious sedation or general anesthesia in an outpatient interventional suite or hospital interventional radiology (IR) department.

    Pre-procedure workflow includes review of recent imaging and labs (coagulation profile, platelets), informed consent discussing risks (bleeding, infection, adjacent organ injury), and percutaneous planning with ultrasound or CT guidance. During the procedure, the operator inserts cryoprobes through the skin into the target lesions using image guidance, performs controlled freeze–thaw cycles to ablate tumor tissue, monitors iceball formation, and confirms ablation extent. Post-procedure monitoring occurs in recovery for vital signs, pain control, and evaluation for immediate complications prior to discharge with follow-up imaging planned to assess treatment response.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    77012CT guidance for needle placement (eg, tumor localization)Often used to report CT guidance during percutaneous probe placement for cryoablation.
    76942Ultrasound guidance for needle placementUsed when ultrasound guidance is the primary imaging modality for probe placement.
    70450CT head without contrastData not applicable to liver; Data not available in the input.
    99223Initial hospital care, typically 70 minutes or moreMay represent inpatient initial evaluation for patients admitted for the procedure.
    96372Therapeutic, prophylactic, or diagnostic injection (e.g., medication administration)May be used for IV sedation medications or adjunctive injections if reportable in the setting.

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RC0000X
    207L00000X
    2086S0122X
    207QH0002X
    101Y00000X
    2085R0203X
    261QM1103X
    2471M1202X

    Related Payer Policy Updates

    Specialty: General Surgery1 / 3

    10 rows

    PolicyPayerEffective Date
    Surgical ProceduresUnitedHealthcare2026-09-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01

    Related Codes

    CPT-47380-OPEN-RADIOFREQUENCY-ABLATION-LIVER

    CPT 47380: Open Radiofrequency Ablation of Liver Tumor

    CPT-47381-OPEN-LIVER-CRYOABLATION

    CPT 47381: Open Cryosurgical Ablation of Liver Tumors

    CPT-47382-PERCUTANEOUS-RADIOFREQUENCY-ABLATION-LIVER-TUMOR

    CPT 47382: Percutaneous Radiofrequency Ablation of Liver Tumors

    CPT-47384-IRREVERSIBLE-ELECTROPORATION-LIVER-TUMOR-ABLATION-PERCUTANEOUS

    CPT 47384: Percutaneous Irreversible Electroporation Ablation of Liver Tumor(s)

    CPT-47399-UNLISTED-LIVER-PROCEDURE

    CPT 47399: Unlisted Procedure, Liver

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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