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    v1.0.31
    OpenPayerBilling CodesEndoscopic Stomal ProceduresCPT cpt-44386-endoscopic-pouchoscopy-with-biopsy
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    CPT 44386: Endoscopic Examination of Ileal Pouch with Biopsy

    Medicare pays $362 on average nationally for this procedure.

    CPT code 44386 describes endoscopic examination of a previously created small intestinal (ileal) pouch and the pouch-anal anastomosis with performance of one or more biopsies of suspicious mucosal areas; service type: endoscopic diagnostic procedure with biopsy; typical site of service: ambulatory endoscopy suite or hospital outpatient endoscopy unit.

    For related coverage guidance, see recent payer policy updates: Diabetic Supplies, Radiofrequency Ablation for Thyroid Nodules, Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Idaho Only).

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult with a history of restorative proctocolectomy with ileal pouch–anal anastomosis (IPAA) presenting for surveillance or evaluation of pouch symptoms such as increased stool frequency, rectal pain, bleeding, or suspected pouchitis. The patient arrives to an outpatient endoscopy suite or ambulatory surgical center after bowel prep and informed consent. The colorectal surgeon or gastroenterologist performs a flexible pouchoscopy by passing a colonoscope/endoscope through the anus to inspect the ileal pouch mucosa and the ileal pouch–anal anastomosis. The provider documents mucosal appearance, inflammation, strictures, or suspicious lesions. If abnormal areas are identified, targeted biopsies are obtained and specimens are submitted to pathology with appropriate labeling. Procedure documentation includes indication, findings, specimens collected, anesthesia/sedation used, and post-procedure recovery instructions. Typical sites of service are the ambulatory endoscopy suite, outpatient hospital endoscopy unit, or office-based surgical suite.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    44388Endoscopy, enteroscopy, via stoma or small intestine with biopsy, single or multipleMay be used when access to the small intestine through a stoma or enteric route is required instead of transanal pouchoscopy.
    45380Colonoscopy, flexible; with biopsy, single or multipleCommonly performed for surveillance of the colon in patients with prior colectomy or to evaluate proximal bowel; similar technique and biopsy component.
    44387Endoscopy, small intestine (enteroscopy), via stoma or per oral, diagnostic, with or without collection of specimen(s) by brushing or washingRelated small-bowel endoscopic procedures when additional small intestine evaluation is needed beyond the pouch.
    44385Intubation of ileostomy or small bowel for endoscopic evaluation, diagnosticUsed when alternative access via ileostomy is employed for visualization or biopsy of the small bowel or pouch.
    88305Level IV surgical pathology, gross and microscopic examinationRepresents typical CPT code for processing and interpretation of biopsy specimens obtained during pouchoscopy; billed by pathology services.

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…
    74Modifier ‑74 indicates an outpatient hospital or ASC procedure that was discontinued after anesthesia was administered and after the procedure had begun. Use this modifier when anesthesia (local,…- Use modifier -74 when a procedure in an outpatient hospital or ASC setting is terminated after anesthesia has been administered and after the procedure has commenced (for example, after incision,…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RC0000X
    207K00000X
    208000000X
    204D00000X
    332U00000X
    246ZE0500X
    207YX0905X
    111NI0900X

    Related ICD-10-CM Codes

    26 rows

    ICD-10-CM CodeDescription
    A09Infectious gastroenteritis and colitis, unspecified
    B95.61Methicillin susceptible Staphylococcus aureus infection as the cause of diseases classified elsewhere
    C17.9Malignant neoplasm of small intestine, unspecified
    C20Malignant neoplasm of rectum
    D12.6Benign neoplasm of colon, unspecified
    K50.919Crohn's disease, unspecified, with unspecified complications
    K51.419Inflammatory polyps of colon with unspecified complications
    K52.89Other specified noninfective gastroenteritis and colitis
    K52.9Noninfective gastroenteritis and colitis, unspecified
    K57.30Diverticulosis of large intestine without perforation or abscess without bleeding

    Showing 1–10 of 26

    Related Payer Policy Updates

    Specialty: Endocrinology1 / 3

    10 rows

    PolicyPayerEffective Date
    Diabetic SuppliesCigna2026-10-15
    Radiofrequency Ablation for Thyroid NodulesCigna2026-10-15
    Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Idaho Only)UnitedHealthcare2026-10-01
    Tzield (teplizumab-mzwv) CoverageUnitedHealthcare2026-10-01
    Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Indiana Only)UnitedHealthcare2026-10-01
    Medical Necessity Guidelines Insulin PumpsMass General Brigham Health Plan2026-10-01
    Medical Necessity Guidelines: Continuous Glucose MonitorsMass General Brigham Health Plan2026-10-01
    Continuous Glucose MonitoringAmbetter Nevada2026-10-01
    Salivary Hormone TestingOscar Health2026-10-01
    Bone Turnover Markers TestingOscar Health2026-10-01

    Related Codes

    CPT-44380-STOMAL-ILEOSCOPY-ENDOSCOPIC-ILEUM-EXAMINATION

    CPT 44380: Ileoscopy via Stoma with Brushings or Washings

    CPT-44381-ILEOSCOPY-THROUGH-STOMA-WITH-BALLOON-DILATION

    CPT 44381: Ileoscopy via Stoma with Endoscopic Balloon Dilation

    CPT-44382-ILEOSCOPY-THROUGH-STOMA-BIOPSY

    CPT 44382: Ileoscopy Through Stoma with Biopsy

    CPT-44384-ILEOSCOPY-WITH-STENT-PLACEMENT-THROUGH-STOMA

    CPT 44384: Ileoscopy with Endoscopic Stent Placement via Stoma

    CPT-44385-ILEAL-POUCH-ENDOSCOPIC-EVALUATION-WITH-BIOPSY-WASHINGS

    CPT 44385: Endoscopic Evaluation of Ileal Pouch with Brushings/Washings

    CPT-44388-COLONOSCOPY-VIA-COLOSTOMY-STOMA-SURVEILLANCE

    CPT 44388: Colonoscopy Through Colostomy Stoma for Evaluation

    CPT-44389-STOMAL-COLONOSCOPY-WITH-BIOPSY

    CPT 44389: Endoscopic Colon Examination Through Stoma with Biopsy

    CPT-44390-COLONOSCOPY-THROUGH-COLOSTOMY-STOMA-FOREIGN-BODY-REMOVAL

    CPT 44390: Colonoscopy via Colostomy for Foreign Body Removal

    CPT-44391-COLONOSCOPY-VIA-COLOSTOMY-STOMA-THERAPEUTIC-EVALUATION

    CPT 44391: Colonoscopy via Colostomy Stoma with Hemostasis

    CPT-44392-COLONOSCOPY-THROUGH-COLOSTOMY-LESION-EXCISION

    CPT 44392: Colonoscopy via Colostomy Stoma with Polypectomy

    Showing 1–10 of 19

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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