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    v1.0.30
    OpenPayerBilling CodesEndoscopic Small Intestine ProceduresCPT cpt-44366-upper-small-bowel-endoscopy-hemostasis
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    CPT 44366: Endoscopic Small-Bowel Exam Beyond Duodenum with Hemostasis

    Medicare pays $215 on average nationally for this procedure.

    CPT code 44366 describes an endoscopic examination of the small intestine that advances beyond the second portion of the duodenum but does not include the ileum, with contemporaneous control of bleeding using techniques such as injection, cautery, heater probe, laser, stapler, or plasma coagulator; this represents an endoscopic therapeutic small-bowel procedure typically performed by a gastroenterologist in an endoscopy suite or hospital outpatient setting for diagnostic visualization and hemostasis.

    For related coverage guidance, see recent payer policy updates: Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disorders, Esophagogastroduodenoscopy (EGD) Coverage Policy, Radiofrequency Therapy for Fecal Incontinence.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old male with a history of chronic melena and iron-deficiency anemia presents for evaluation. Prior upper endoscopy to the second portion of the duodenum was nondiagnostic for a bleeding source. The gastroenterologist schedules a diagnostic and therapeutic small bowel endoscopy that advances beyond the second portion of the duodenum but does not include ileal intubation. The procedure is performed in an outpatient endoscopy suite under moderate sedation administered by anesthesia staff. The provider advances an endoscope past the ligament of Treitz into the proximal jejunum, identifies an actively bleeding angiodysplasia, and achieves hemostasis using cautery and injection therapy. Vital signs are monitored, informed consent is documented, pre-procedure antibiotics are given only if indicated, and a post-procedure recovery period with discharge instructions and follow-up is completed. Typical site of service: outpatient endoscopy center or hospital outpatient department. Service type: diagnostic and therapeutic small bowel endoscopy with endoscopic hemostasis.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    43235Upper gastrointestinal endoscopy including esophagus, stomach, and either the duodenum or jejunum; diagnostic, flexible, transoralOften performed prior to or instead of small bowel endoscopy when upper GI source is suspected; may be part of combined diagnostic strategy.
    44388Endoscopic small bowel biopsy, single or multiplePerformed during small bowel endoscopy when tissue diagnosis is required for celiac disease, inflammation, or pathology identified during the procedure.
    45378Colonoscopy, flexible; diagnostic, including collection of specimen(s) by brushing or washing, when performed (separate code for therapeutic)May be performed in the same diagnostic workup for lower GI bleeding or chronic anemia; different anatomic region but common companion procedure.
    43239Upper GI endoscopy with biopsy, single or multipleIf mucosal biopsies are obtained during the examination beyond the second portion of the duodenum.
    43258Upper GI endoscopy with control of bleeding, any methodAlternative/similar code used when hemostasis is performed in the proximal small bowel during an upper endoscopic approach; coding choice depends on anatomical extent and documentation.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RG0100X
    207RC0200X
    2080P0207X
    207L00000X
    332BC3200X
    207W00000X
    2085P0229X
    211D00000X

    Related Payer Policy Updates

    Specialty: Gastroenterology1 / 3

    10 rows

    PolicyPayerEffective Date
    Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disordersbcbsvermont2026-12-01
    Esophagogastroduodenoscopy (EGD) Coverage Policyevicore2026-11-05
    Radiofrequency Therapy for Fecal IncontinenceCigna2026-10-15
    Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD)univerahealthcare2026-10-15
    High-Resolution Anoscopy (HRA)Premera Bluecross2026-10-01
    Gastroesophageal and Gastrointestinal (GI) Services and ProceduresColorado Rocky Mountain Health Plans2026-10-01
    Fecal Analysis in the Diagnosis of Intestinal Dysbiosis and Fecal Microbiota Transplant TestingOscar Health2026-10-01
    Serum Testing for Hepatic Fibrosis in the Evaluation and Monitoring of Chronic Liver DiseaseOscar Health2026-10-01
    Pancreatic Enzyme Testing for Acute PancreatitisOscar Health2026-10-01
    Helicobacter pylori TestingOscar Health2026-10-01

    Related Codes

    CPT-44360-UPPER-SMALL-BOWEL-ENDOSCOPY-JEJUNUM-BRUSHING

    CPT 44360: Endoscopic Exam of Duodenum and Jejunum with Brushing

    CPT-44361-ENDOSCOPY-PROXIMAL-SMALL-INTESTINE-BIOPSY

    CPT 44361: Endoscopy Beyond Second Duodenum with Biopsy

    CPT-44363-ENDOSCOPIC-JEJUNAL-INTUBATION-FOREIGN-BODY-REMOVAL

    CPT 44363: Endoscopy of Duodenum and Jejunum with Foreign Body Removal

    CPT-44364-SMALL-BOWEL-ENDOSCOPY-SNARE-POLYPECTOMY

    CPT 44364: Small-Bowel Enteroscopy with Snare Polypectomy

    CPT-44365-SMALL-INTESTINE-ENDOSCOPY-LESION-REMOVAL

    CPT 44365: Endoscopy Beyond Second Duodenum with Hot Biopsy or Bipolar Cautery

    CPT-44369-ENDOSCOPIC-LASER-RADIOFREQUENCY-ABLATION-SMALL-BOWEL

    CPT 44369: Endoscopic Small Bowel Laser/Radiofrequency Ablation

    CPT-44370-UPPER-GI-ENDOSCOPY-DILATION-STENT-PLACEMENT

    CPT 44370: Endoscopic Dilation and Stent Placement in Upper GI

    CPT-44372-ENDOSCOPIC-JEJUNAL-FEEDING-TUBE-PLACEMENT

    CPT 44372: Endoscopic Jejunostomy Tube Placement

    CPT-44373-GASTROSTOMY-TO-JEJUNOSTOMY-CONVERSION-ENDOSCOPIC

    CPT 44373: Conversion of Gastrostomy Tube to Jejunostomy via Abdominal Approach

    CPT-44376-DIAGNOSTIC-UPPER-ENDOSCOPY-BRUSHING-LAVAGE

    CPT 44376: Upper GI Endoscopy with Brush Cytology

    Showing 1–10 of 13

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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