Loading...

    Explore
    • Policy Monitoring
    • Live Policy Feed
    • Billing Codes
    • Healthcare Providers
    • Health Insurance Payers
    • States
    • Service Lines
    • Taxonomy Codes
    Lookup tools
    • Billing Code Lookup
    • CPT Modifier Lookup
    • Provider Taxonomy Code Lookup
    • Healthcare Provider & Facility Lookup
    • Health Insurance Payer Lookup
    • Payer Contact Directory

    Policy & Benchmark Tools

    • Prior Authorization Lookup
    • Coverage Criteria Lookup
    • Timely Filing Lookup
    • Billing Code Reimbursement Rates
    • Payer Comparison Dashboard
    • Facility Comparison Dashboard
    • All tools

    Company

    • About OpenPayer
    • Data Sources
    • Trek Health
    OpenPayerby Trek Health
    LinkedInYouTube

    © 2026 Trek Health. All rights reserved.

    OpenPayer is built and maintained by Trek Health.

    v1.0.30
    OpenPayerBilling CodesExcision Procedures on the Salivary Gland and DuctsCPT cpt-42450-sublingual-gland-excision
    Ask Trek AI about this page

    CPT 42450: Excision of Sublingual Gland

    Medicare pays $487 on average nationally for this procedure.

    CPT code 42450 describes the surgical removal of the sublingual gland (sublingual gland excision), a operative procedure typically performed by an otolaryngologist or oral and maxillofacial surgeon in an operating room or ambulatory surgical center under general or local anesthesia; the service involves excision of the sublingual salivary gland for indications such as chronic sialadenitis, ranula, or salivary gland obstruction.

    For related coverage guidance, see recent payer policy updates: Orthopedic Joint Procedures of the Knee for Managed Medicaid (MMC), Health and Recovery Plan (HARP), Child Health Plus (CHP), and Essential Plan (EP) Members, Autologous Chondrocyte Transplantation or Implantation Corporate Medical Policy, Autologous Platelet-Derived Growth Factors (Platelet-Rich Plasma [PRP]).

    Customize your policy alerts

    Sign up for cpt 42450 policy alerts

    Get alerted when payer policies referencing 42450 are released or updated.

    Monitor payer policy activity

    Receive email alerts as soon as relevant payer policies are published or updated.

    Table of contents

    Progress1 / 7

    Explore openpayer tools

    • Billing CodesCPT, HCPCS, DRG & more
    • Reimbursement RatesCommercial vs. Medicare rate reports
    • Facility ComparisonBeds, revenue & payer mix
    • ProvidersHospitals & facilities
    • PayersPlans & market footprint
    • Taxonomy CodesNUCC specialty codes
    • ModifiersCPT modifiers & usage
    • Prior AuthorizationPA policies by payer & drug
    • Timely FilingFiling deadlines by payer
    • Coverage CriteriaMedical necessity by payer
    • Payer ContactsClaims, PA & appeals contacts
    View all tools

    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult presenting with persistent sublingual swelling, recurrent mucous retention (ranula), chronic infection, or painful mass beneath the tongue that has failed conservative management. The workflow begins with an otolaryngology or oral and maxillofacial surgery clinic evaluation including history, oral exam, and imaging (ultrasound or CT/MRI) to assess gland size, ductal obstruction, and relation to surrounding structures. Preoperative counseling addresses anesthesia (local with sedation or general), risks (bleeding, infection, nerve injury), and alternatives. On the day of service the patient is prepared in an ambulatory surgical center or hospital outpatient operating room; regional or general anesthesia is administered. The surgeon performs an intraoral approach to excise the sublingual gland, achieves hemostasis, inspects for adjacent duct or nerve injury, and closes mucosal incisions. Postoperative care includes short-term oral antibiotics as indicated, analgesia, instructions for oral hygiene, and a follow-up visit to assess healing and remove sutures if needed. Typical sites of service are the ambulatory surgical center or hospital outpatient department. Common clinical scenarios include symptomatic ranula excision, recurrent sialadenitis of the sublingual gland, or space-occupying lesions requiring removal.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    42420Excision of submandibular gland, unilateralPerformed for submandibular gland disease; may be related when broader salivary gland disease is present or diagnostic uncertainty exists.
    42410Excision of sublingual and submandibular ducts or diverticulum (separate)May be performed if ductal pathology requires concurrent management.
    42640Excision of ranula, intraoral approachOften performed in conjunction with sublingual gland excision for ranula management; some clinicians excise both the gland and ranula.
    40490Biopsy, mouth mucosa; single or multipleUsed preoperatively or intraoperatively to sample suspicious mucosal lesions adjacent to the gland.
    00000Data not available in the input.Data not available in the input.

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…
    74Modifier ‑74 indicates an outpatient hospital or ASC procedure that was discontinued after anesthesia was administered and after the procedure had begun. Use this modifier when anesthesia (local,…- Use modifier -74 when a procedure in an outpatient hospital or ASC setting is terminated after anesthesia has been administered and after the procedure has commenced (for example, after incision,…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207R00000X
    207L00000X
    363L00000X
    261QR0400X
    2085N0700X
    126800000X
    156FX1101X
    2278C0205X

    Related ICD-10-CM Codes

    23 rows

    ICD-10-CM CodeDescription
    E86.0Dehydration
    F45.41Pain disorder exclusively related to psychological factors
    G47.00Insomnia, unspecified
    I83.90Asymptomatic varicose veins of unspecified lower extremity
    J39.8Other specified diseases of upper respiratory tract
    K11.3Abscess of salivary gland
    K11.4Fistula of salivary gland
    K11.5Sialolithiasis
    K11.6Mucocele of salivary gland
    K11.7Disturbances of salivary secretion

    Showing 1–10 of 23

    Related Payer Policy Updates

    Specialty: Orthopedics/Musculoskeletal1 / 3

    10 rows

    PolicyPayerEffective Date
    Orthopedic Joint Procedures of the Knee for Managed Medicaid (MMC), Health and Recovery Plan (HARP), Child Health Plus (CHP), and Essential Plan (EP) Membersuniverahealthcare2027-01-01
    Autologous Chondrocyte Transplantation or Implantation Corporate Medical Policybcbsvermont2026-12-01
    Autologous Platelet-Derived Growth Factors (Platelet-Rich Plasma [PRP])Cigna2026-10-15
    Metatarsophalangeal Joint ReplacementCigna2026-10-15
    Shoulder Arthroplasty (Total, Partial, Reverse, Revision and Resurfacing)univerahealthcare2026-10-15
    Hip Arthroplasty (partial and total hip replacement)univerahealthcare2026-10-15
    Artificial Lumbar Intervertebral Disc (Lumbar Total Disc Arthroplasty)univerahealthcare2026-10-15
    Osteochondral Grafting of the Kneeuniverahealthcare2026-10-15
    Lumbar Fusion (arthrodesis) with decompressionuniverahealthcare2026-10-15
    Metal-on-Metal Total Hip Resurfacinguniverahealthcare2026-10-15

    Related Codes

    CPT-42400-PERCUTANEOUS-SALIVARY-GLAND-BIOPSY

    CPT 42400: Percutaneous Needle Biopsy of Salivary Gland

    CPT-42405-SALIVARY-GLAND-BIOPSY-EXTERNAL-INCISION

    CPT 42405: Open Incisional Biopsy of Salivary Gland

    CPT-42408-RANULA-EXCISION-FLOOR-OF-MOUTH

    CPT 42408: Excision of Ranula, Floor of Mouth

    CPT-42409-MARSUPIALIZATION-SUBLINGUAL-SALIVARY-CYST

    CPT 42409: Marsupialization of Sublingual Salivary Cyst

    CPT-42410-PAROTID-LATERAL-LOBE-TUMOR-EXCISION-NO-NERVE-DISSECTION

    CPT 42410: Excision of Tumor, Lateral Lobe of Parotid Gland, No Nerve Dissection

    CPT-42415-PAROTID-LATERAL-LOBE-EXCISION-FACIAL-NERVE-PRESERVATION

    CPT 42415: Parotidectomy, Lateral Lobe Excision with Facial Nerve Preservation

    CPT-42420-PAROTIDECTOMY-FACIAL-NERVE-PRESERVATION

    CPT 42420: Parotidectomy with Facial Nerve Preservation

    CPT-42425-PAROTID-GLAND-REMOVAL-EN-BLOC-WITHOUT-FACIAL-NERVE-PRESERVATION

    CPT 42425: Parotid Gland Removal with Tumor (Non–Nerve-Sparing)

    CPT-42426-PAROTIDECTOMY-TOTAL-WITH-RADICAL-NECK-DISSECTION-UNILATERAL

    CPT 42426: Total Parotidectomy for Tumor with Unilateral Radical Neck Dissection

    CPT-42440-SUBMANDIBULAR-GLAND-EXCISION

    CPT 42440: Submandibular Gland Excision

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
    Published by

    Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.