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    v1.0.30
    OpenPayerBilling CodesExcision Procedures on the Salivary Gland and DuctsCPT cpt-42440-submandibular-gland-excision
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    CPT 42440: Submandibular Gland Excision

    Medicare pays $378 on average nationally for this procedure.

    CPT code 42440 describes the surgical excision of a submandibular gland, a procedure typically performed by an otolaryngologist or oral and maxillofacial surgeon as an operative head and neck procedure; the service type is a surgical gland excision and the typical site of service is an operating room or ambulatory surgery center for removal of the submandibular salivary gland.

    For related coverage guidance, see recent payer policy updates: Orthopedic Joint Procedures of the Knee for Managed Medicaid (MMC), Health and Recovery Plan (HARP), Child Health Plus (CHP), and Essential Plan (EP) Members, Autologous Chondrocyte Transplantation or Implantation Corporate Medical Policy, Autologous Platelet-Derived Growth Factors (Platelet-Rich Plasma [PRP]).

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult presenting with chronic submandibular gland swelling, recurrent sialadenitis, or a radiopaque salivary stone causing obstructive symptoms. Evaluation includes history, physical exam noting a firm or tender submandibular mass, ultrasound or CT to identify gland enlargement or sialolithiasis, and needle aspiration or culture if infection is suspected. When conservative measures (hydration, sialogogues, antibiotics, or gland-sparing endoscopic stone removal) are unsuccessful or not feasible, the surgeon schedules a definitive operative excision of the submandibular gland.

    The procedure is performed in an operating room or ambulatory surgical center under general anesthesia with or without regional nerve monitoring. The workflow includes preoperative informed consent, pre-op antibiotics per facility protocol, patient positioning with a submandibular skin crease incision, meticulous dissection to identify and preserve the marginal mandibular branch of the facial nerve and lingual nerve, ligation of the facial artery and Wharton duct, gland removal, hemostasis, layered closure, and recovery monitoring. Postoperative care includes pain control, wound care instructions, short course antibiotics if indicated, and follow-up to assess nerve function and wound healing.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    60252Excision of submandibular gland, partialPerformed when only part of the gland is removed for focal disease; alternative to complete excision
    42445Excision of sublingual glandRelated salivary gland excision; may be performed if concurrent sublingual disease exists
    42820Excision of branchial cleft cyst or sinus tractExample of nearby neck soft-tissue procedures that may be performed in the same operative field when indicated
    70110Radiologic examination, jaw (panoramic)Preoperative imaging study sometimes used to localize sialoliths or assess anatomy prior to excision
    76536Ultrasound, salivary glandsCommon diagnostic imaging used preoperatively to evaluate gland size, stones, and masses
    43260Endoscopic removal of salivary stone (sialendoscopy)Minimally invasive alternative or adjunct for stone removal; may precede or obviate gland excision

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208C00000X
    2080P0207X
    207P00000X
    2084P0800X
    207Q00000X
    363LN0000X
    261QM0801X
    163WX1500X

    Related Payer Policy Updates

    Specialty: Orthopedics/Musculoskeletal1 / 3

    10 rows

    PolicyPayerEffective Date
    Orthopedic Joint Procedures of the Knee for Managed Medicaid (MMC), Health and Recovery Plan (HARP), Child Health Plus (CHP), and Essential Plan (EP) Membersuniverahealthcare2027-01-01
    Autologous Chondrocyte Transplantation or Implantation Corporate Medical Policybcbsvermont2026-12-01
    Autologous Platelet-Derived Growth Factors (Platelet-Rich Plasma [PRP])Cigna2026-10-15
    Metatarsophalangeal Joint ReplacementCigna2026-10-15
    Shoulder Arthroplasty (Total, Partial, Reverse, Revision and Resurfacing)univerahealthcare2026-10-15
    Hip Arthroplasty (partial and total hip replacement)univerahealthcare2026-10-15
    Artificial Lumbar Intervertebral Disc (Lumbar Total Disc Arthroplasty)univerahealthcare2026-10-15
    Osteochondral Grafting of the Kneeuniverahealthcare2026-10-15
    Lumbar Fusion (arthrodesis) with decompressionuniverahealthcare2026-10-15
    Metal-on-Metal Total Hip Resurfacinguniverahealthcare2026-10-15

    Related Codes

    CPT-42400-PERCUTANEOUS-SALIVARY-GLAND-BIOPSY

    CPT 42400: Percutaneous Needle Biopsy of Salivary Gland

    CPT-42405-SALIVARY-GLAND-BIOPSY-EXTERNAL-INCISION

    CPT 42405: Open Incisional Biopsy of Salivary Gland

    CPT-42408-RANULA-EXCISION-FLOOR-OF-MOUTH

    CPT 42408: Excision of Ranula, Floor of Mouth

    CPT-42409-MARSUPIALIZATION-SUBLINGUAL-SALIVARY-CYST

    CPT 42409: Marsupialization of Sublingual Salivary Cyst

    CPT-42410-PAROTID-LATERAL-LOBE-TUMOR-EXCISION-NO-NERVE-DISSECTION

    CPT 42410: Excision of Tumor, Lateral Lobe of Parotid Gland, No Nerve Dissection

    CPT-42415-PAROTID-LATERAL-LOBE-EXCISION-FACIAL-NERVE-PRESERVATION

    CPT 42415: Parotidectomy, Lateral Lobe Excision with Facial Nerve Preservation

    CPT-42420-PAROTIDECTOMY-FACIAL-NERVE-PRESERVATION

    CPT 42420: Parotidectomy with Facial Nerve Preservation

    CPT-42425-PAROTID-GLAND-REMOVAL-EN-BLOC-WITHOUT-FACIAL-NERVE-PRESERVATION

    CPT 42425: Parotid Gland Removal with Tumor (Non–Nerve-Sparing)

    CPT-42426-PAROTIDECTOMY-TOTAL-WITH-RADICAL-NECK-DISSECTION-UNILATERAL

    CPT 42426: Total Parotidectomy for Tumor with Unilateral Radical Neck Dissection

    CPT-42450-SUBLINGUAL-GLAND-EXCISION

    CPT 42450: Excision of Sublingual Gland

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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