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    v1.0.30
    OpenPayerBilling CodesOther Transcatheteral ProceduresCPT cpt-37214-catheter-directed-thrombolytic-infusion
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    CPT 37214: Catheter-Directed Thrombolysis for Noncoronary Vessels

    Medicare pays $108 on average nationally for this procedure.

    CPT code 37214 describes catheter-directed thrombolysis in which a provider inserts a catheter into an artery or vein to deliver thrombolytic medication to a clot, including radiological supervision and interpretation; the service type is catheter-directed thrombolytic infusion and the typical site of service is an interventional radiology suite, vascular procedure room, or other hospital-based procedure area for noncoronary vessels.

    For related coverage guidance, see recent payer policy updates: Automated Ambulatory Blood Pressure Monitoring for Diagnosis of Hypertension in Patients with Elevated Office Blood Pressure, Cardiology - Ivabradine, Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA).

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 68-year-old patient presents with acute limb ischemia of the left lower extremity characterized by sudden onset pain, pallor, decreased pulses, and sensory deficit. Vascular imaging (CTA or duplex) identifies an occlusive thrombus within the popliteal and proximal tibial arteries. The interventional radiology or vascular surgery team admits the patient for catheter-directed thrombolytic therapy. On the initial day, an angiographic catheter is placed into the affected arterial segment and a bolus plus continuous infusion of a thrombolytic agent is started under continuous hemodynamic and laboratory monitoring. Radiological supervision and interpretation are provided during catheter placement and infusion adjustments. Over subsequent hospital days, the patient undergoes one or more subsequent infusion treatment days where the catheter is repositioned as needed, catheter contrast injections are performed to assess lysis progress, and the infusion is continued. On the final treatment day, the thrombolytic infusion is stopped, the catheter is removed, and the arterial access site is closed by percutaneous means.

    Typical workflow elements include pre-procedure consent and coagulation assessment, image-guided catheter placement and diagnostic angiography, initiation of thrombolytic infusion, daily radiologic assessment with possible catheter repositioning or contrast injections, monitoring by the clinical team for bleeding or reperfusion, and final cessation of therapy with catheter removal and vessel closure.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    36200Introduction of catheter, arterial system; for diagnostic angiography, initial vessel catheterizationMay be performed immediately prior to 37214 for diagnostic angiography and arterial access
    36245Selective catheterization, iliac, or lower extremity arteriesUsed when selective catheter placement is needed to localize thrombolytic infusion site before or during 37214
    37211Transcatheter therapy, percutaneous, infusion for thrombolysis; initial treatment day, non-coronaryRepresents the initial-day catheter-directed thrombolysis; 37214 is used for subsequent treatment days or termination of therapy
    76000Fluoroscopy (separate procedure)Fluoroscopic guidance and imaging are integral to catheter placement and monitoring during 37214; imaging components may be reported per payer rules
    93010Electrocardiogram interpretation and reportMay be performed as part of monitoring during thrombolytic therapy when cardiac monitoring is clinically indicated

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RG0100X
    208600000X
    207P00000X
    3336C0004X
    207L00000X
    2082S0105X
    374T00000X
    2471N0900X

    Related Payer Policy Updates

    Specialty: Cardiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Automated Ambulatory Blood Pressure Monitoring for Diagnosis of Hypertension in Patients with Elevated Office Blood PressureBluecross Idaho2026-11-01
    Cardiology - IvabradineCigna2026-10-15
    Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA)univerahealthcare2026-10-15
    Percutaneous Ventricular Assist DeviceUnitedHealthcare2026-10-01
    Cardiovascular Disease Risk AssessmentOscar Health2026-10-01
    Biomarkers for Myocardial Infarction and Chronic Heart FailureOscar Health2026-10-01
    Multiple Procedure Payment Reduction for Diagnostic Cardiovascular ProceduresBlue Cross Blue Shield - Maine2026-10-01
    Left Atrial Appendage Closure Devicesexcellus_health_plan_inc2026-09-17
    Left Atrial Appendage Closure Devicesuniverahealthcare2026-09-17
    Cardiac Omnibus CodesCigna2026-09-15

    Related Codes

    CPT-37191-INFERIOR-VENA-CAVA-FILTER-PLACEMENT

    CPT 37191: Inferior Vena Cava Filter Placement, Percutaneous

    CPT-37192-IVC-FILTER-REPOSITIONING-IMAGE-GUIDED

    CPT 37192: Reposition Inferior Vena Cava Filter

    CPT-37193-IVC-FILTER-REMOVAL-PERCUTANEOUS

    CPT 37193: Percutaneous IVC Filter Removal

    CPT-37195-CEREBRAL-THROMBOLYTIC-INFUSION

    CPT 37195: Catheter-Directed Intracerebral Thrombolytic Infusion

    CPT-37197-PERCUTANEOUS-ENDOVASCULAR-FOREIGN-BODY-REMOVAL

    CPT 37197: Endovascular Percutaneous Removal of Foreign Body

    CPT-37200-TRANSCATHETER-VASCULAR-BIOPSY

    CPT 37200: Transcatheter Vascular Biopsy

    CPT-37211-CATHETER-DIRECTED-THROMBOLYSIS-ARTERIAL

    CPT 37211: Catheter-Directed Arterial Thrombolysis, Initial Day

    CPT-37212-CATHETER-DIRECTED-THROMBOLYSIS-VENOUS

    CPT 37212: Catheter-Directed Venous Thrombolysis with Radiologic Supervision

    CPT-37213-CATHETER-DIRECTED-THROMBOLYTIC-INFUSION

    CPT 37213: Catheter-Directed Thrombolysis, Subsequent Day (Noncoronary)

    CPT-37215-CAROTID-ARTERY-STENT-PLACEMENT-EMBOLIC-PROTECTION

    CPT 37215: Carotid Artery Stent Placement with Embolic Protection

    Showing 1–10 of 13

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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