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    v1.0.30
    OpenPayerBilling CodesOther Transcatheteral ProceduresCPT cpt-37212-catheter-directed-thrombolysis-venous
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    CPT 37212: Catheter-Directed Venous Thrombolysis with Radiologic Supervision

    Medicare pays $296 on average nationally for this procedure.

    CPT code 37212 describes catheter-directed thrombolysis performed in a vein where the provider inserts a catheter to infuse thrombolytic medication at the site of a clot and provides radiological supervision and interpretation for vessel access; service type: endovascular thrombolytic therapy, typical site of service: interventional radiology suite or vascular procedure room.

    For related coverage guidance, see recent payer policy updates: Automated Ambulatory Blood Pressure Monitoring for Diagnosis of Hypertension in Patients with Elevated Office Blood Pressure, Cardiology - Ivabradine, Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA).

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    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old patient presents with progressive unilateral lower extremity swelling, pain, and decreased dorsalis pedis pulse over 24–48 hours. Duplex ultrasound demonstrates extensive acute deep venous thrombosis of the femoral and popliteal veins with concern for limb-threatening ischemia or significant symptom burden. Interventional radiology evaluates the patient and recommends catheter-directed thrombolysis for targeted clot dissolution. On the initial treatment day the interventionalist obtains informed consent, performs venous access (commonly popliteal or common femoral), advances a multi-sidehole infusion catheter into the thrombus, administers a thrombolytic agent via the catheter, and provides radiological supervision and interpretation (fluoroscopic guidance, contrast injections to confirm position). Post-procedure care includes ICU or step-down monitoring for bleeding and neurovascular checks, serial labs (hematology and fibrinogen), and imaging follow-up. Typical sites of service are the hospital interventional suite or the inpatient radiology department, often billed as an inpatient procedure on day 0 (initial day of catheter-directed thrombolytic infusion).

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    37211Catheter-directed thrombolysis, peripheral; infusion only (initial treatment day)Often billed for subsequent days of continuous infusion when no vascular access or thrombolytic infusion catheter placement is performed that day; complements 37212 when infusion continues.

    | 37213 | Catheter-directed thrombolysis, peripheral, including radiological supervision and interpretation, and power injection(s) when performed; infusion followed by pharmacomechanical thrombolysis (initial treatment day) | Used when pharmacomechanical thrombolysis (mechanical fragmentation or aspiration) is performed in addition to catheter-directed infusion on the initial day.

    | 36010 | Introduction of needle or intracatheter, central venous access, without subcutaneous port or pump, age 5 years or older | May be used if separate central venous access is required for infusion unrelated to the thrombolysis catheter (billing dependent on documentation).

    | 75989 | Other vascular interpretation, including radiological supervision and interpretation | Used for additional diagnostic venography or advanced interpretation procedures performed during the intervention.

    | 93970 | Duplex scan of extremity veins including responses to compression and other maneuvers; complete bilateral study | Commonly performed pre- and post-procedure to document clot burden and procedural outcome.

    Related Modifiers

    7 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207P00000X
    207RP1001X
    208000000X
    207L00000X
    3336C0002X
    122400000X
    364SS0200X
    202D00000X

    Related Payer Policy Updates

    Specialty: Cardiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Automated Ambulatory Blood Pressure Monitoring for Diagnosis of Hypertension in Patients with Elevated Office Blood PressureBluecross Idaho2026-11-01
    Cardiology - IvabradineCigna2026-10-15
    Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA)univerahealthcare2026-10-15
    Percutaneous Ventricular Assist DeviceUnitedHealthcare2026-10-01
    Cardiovascular Disease Risk AssessmentOscar Health2026-10-01
    Biomarkers for Myocardial Infarction and Chronic Heart FailureOscar Health2026-10-01
    Multiple Procedure Payment Reduction for Diagnostic Cardiovascular ProceduresBlue Cross Blue Shield - Maine2026-10-01
    Left Atrial Appendage Closure Devicesexcellus_health_plan_inc2026-09-17
    Left Atrial Appendage Closure Devicesuniverahealthcare2026-09-17
    Cardiac Omnibus CodesCigna2026-09-15

    Related Codes

    CPT-37191-INFERIOR-VENA-CAVA-FILTER-PLACEMENT

    CPT 37191: Inferior Vena Cava Filter Placement, Percutaneous

    CPT-37192-IVC-FILTER-REPOSITIONING-IMAGE-GUIDED

    CPT 37192: Reposition Inferior Vena Cava Filter

    CPT-37193-IVC-FILTER-REMOVAL-PERCUTANEOUS

    CPT 37193: Percutaneous IVC Filter Removal

    CPT-37195-CEREBRAL-THROMBOLYTIC-INFUSION

    CPT 37195: Catheter-Directed Intracerebral Thrombolytic Infusion

    CPT-37197-PERCUTANEOUS-ENDOVASCULAR-FOREIGN-BODY-REMOVAL

    CPT 37197: Endovascular Percutaneous Removal of Foreign Body

    CPT-37200-TRANSCATHETER-VASCULAR-BIOPSY

    CPT 37200: Transcatheter Vascular Biopsy

    CPT-37211-CATHETER-DIRECTED-THROMBOLYSIS-ARTERIAL

    CPT 37211: Catheter-Directed Arterial Thrombolysis, Initial Day

    CPT-37213-CATHETER-DIRECTED-THROMBOLYTIC-INFUSION

    CPT 37213: Catheter-Directed Thrombolysis, Subsequent Day (Noncoronary)

    CPT-37214-CATHETER-DIRECTED-THROMBOLYTIC-INFUSION

    CPT 37214: Catheter-Directed Thrombolysis for Noncoronary Vessels

    CPT-37215-CAROTID-ARTERY-STENT-PLACEMENT-EMBOLIC-PROTECTION

    CPT 37215: Carotid Artery Stent Placement with Embolic Protection

    Showing 1–10 of 13

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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