CPT code 35305 denotes removal of thrombus and plaque from an initial tibial or peroneal artery, a targeted vascular procedure used to restore distal lower-extremity blood flow. Nationally, procedures addressing tibial and peroneal occlusive disease are important for limb salvage, wound healing, and reducing amputation risk, making accurate coding and payment alignment critical for providers and payers.

Key payers in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of clinical context, typical sites of service, and the service type associated with CPT code 35305. The publication provides benchmarks and policy-relevant details where available, highlights common billing considerations, and outlines the clinical implications of the procedure for vascular care pathways.

This piece is intended for a national audience of clinicians, coding professionals, and payers. It summarizes what CPT code 35305 represents, why it matters to vascular care and reimbursement, and what stakeholders should expect when encountering this code in claims and clinical documentation. Data not available in the input is noted where applicable.