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    OpenPayerBilling CodesThromboendarterectomy Procedures on Arteries and VeinsCPT cpt-35305-tibial-peroneal-artery-thrombectomy-plaque-removal
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    CPT 35305: Thromboendarterectomy of Tibial or Peroneal Artery

    Medicare pays $1100 on average nationally for this procedure.

    CPT code 35305 describes surgical removal of thrombus and atherosclerotic plaque from an initial tibial or peroneal artery, a vascular open procedure to restore distal arterial blood flow; the service is a thromboendarterectomy performed on tibial/peroneal arteries, typically provided as an inpatient or outpatient vascular surgery in an operating room or vascular suite setting.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 68-year-old male with peripheral artery disease presenting with acute or subacute ischemic symptoms of the lower leg and foot (rest pain, non-healing ulcer, or progressive claudication) attributable to an occlusive thrombus or atherosclerotic plaque in a tibial or peroneal artery. The vascular surgeon or interventional radiologist evaluates the patient in clinic and orders arterial duplex ultrasound and/or diagnostic lower-extremity angiography. In the angiography suite or hybrid operating room, after vascular access is obtained (commonly via the common femoral artery), diagnostic angiography confirms an obstructive lesion in an initial tibial or peroneal artery. The provider performs mechanical or catheter-directed thrombectomy and/or plaque extraction to remove thrombus and atheromatous material from the targeted tibial or peroneal vessel. Hemostasis is achieved, and the patient is observed in a post-anesthesia care unit with neurovascular checks and anticoagulation/antiplatelet management as indicated. Typical documentation includes indication, pre-procedure imaging, informed consent, access site, devices used, vessels treated, amount and appearance of thrombus/plaque removed, complications (if any), and post-procedure plan including wound care, medication changes, and follow-up imaging or revascularization planning.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    36247Selective catheter placement, arterial system; each first order intra-arterial branch, within a vascular family, including angiography when performedDiagnostic or access catheterization of tibial/peroneal branches prior to or during thrombectomy
    36248Therapeutic catheter placement, arterial system, each first order intra-arterial branch, within a vascular family (eg, infusion, aspiration), including angiography when performedCatheter-directed therapies such as thrombolytic infusion that may accompany or precede thrombectomy
    37220Revascularization, endovascular, open or percutaneous, tibial-peroneal trunk, including angioplasty and/or stent when performed; initial vesselEndovascular angioplasty/stent of tibial/peroneal vessels performed before or after plaque/thrombus removal
    37799Unlisted procedures, vascular surgeryUsed when an unusual or unlisted vascular technique is performed in conjunction with thrombectomy/plaque removal
    76000Fluoroscopic guidance for vascular catheter placement (list separately in addition to code for primary procedure)Imaging guidance billed in addition to the primary thrombectomy when fluoroscopy is employed

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207K00000X
    207R00000X
    208000000X
    125K00000X
    2278E1000X
    2278C0205X
    1223D0001X
    227900000X

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-35301-CAROTID-VERTEBRAL-SUBCLAVIAN-THROMBOENDARTERECTOMY

    CPT 35301: Thromboendarterectomy/Thrombectomy, Carotid/Vertebral/Subclavian

    CPT-35302-SUPERFICIAL-FEMORAL-ARTERY-THROMBECTOMY-ATHERCTOMY

    CPT 35302: Superficial Femoral Artery Thrombectomy/Endarterectomy

    CPT-35303-POPLITEAL-ARTERY-THROMBUS-PLAQUE-REMOVAL

    CPT 35303: Popliteal Artery Thrombectomy/Endarterectomy

    CPT-35304-TIBIOPERONEAL-TRUNK-THROMBECTOMY-ENDARTERECTOMY

    CPT 35304: Tibioperoneal Trunk Thrombectomy and Plaque Removal

    CPT-35306-ADDITIONAL-TIBIAL-PERONEAL-ARTERY-THROMBOENDARTERECTOMY

    CPT 35306: Additional Tibial or Peroneal Artery Thromboendarterectomy

    CPT-35311-THORACIC-SUBCLAVIAN-INNOMINATE-ARTERY-THROMBECTOMY-ENDARTERECTOMY

    CPT 35311: Subclavian/Innominate Artery Thrombus and Plaque Removal

    CPT-35321-AXILLARY-BRACHIAL-ARTERY-THROMBECTOMY-ENDARTERECTOMY

    CPT 35321: Axillary or Brachial Artery Thrombectomy/Endarterectomy

    CPT-35331-ABDOMINAL-AORTIC-THROMBECTOMY-ENDARTERECTOMY

    CPT 35331: Abdominal Aortic Thrombectomy/Endarterectomy

    CPT-35341-MESENTERIC-CELIAC-RENAL-ARTERY-THROMBUS-PLAQUE-REMOVAL

    CPT 35341: Thrombus/Plaque Removal, Mesenteric/Celiac/Renal Artery

    CPT-35351-ILIAC-ARTERY-THROMBUS-ENDARTERECTOMY

    CPT 35351: Iliac Artery Thrombectomy/Endarterectomy

    Showing 1–10 of 16

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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