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    OpenPayerBilling CodesThromboendarterectomy Procedures on Arteries and VeinsCPT cpt-35303-popliteal-artery-thrombus-plaque-removal
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    CPT 35303: Popliteal Artery Thrombectomy/Endarterectomy

    Medicare pays $1113 on average nationally for this procedure.

    CPT code 35303 describes a surgical vascular procedure in which the provider removes thrombus and atherosclerotic plaque from the popliteal artery; this represents an open arterial thrombectomy/endarterectomy performed on the lower extremity and is typically provided in an operating room or procedural suite as an inpatient or outpatient vascular surgery service.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult with acute or chronic limb ischemia of the lower extremity attributed to an occlusive thrombus or atherosclerotic plaque in the popliteal artery. The patient commonly presents with rest pain, worsening claudication, decreased distal pulses, or threatened tissue viability (cool, pale foot, delayed capillary refill). Initial evaluation includes vascular exam, ankle-brachial index (ABI), arterial duplex ultrasound, and often CT angiography or MR angiography confirming focal thrombus or flow-limiting plaque in the popliteal artery.

    The clinical workflow begins with pre-procedure assessment by a vascular surgeon or interventionalist, review of imaging, optimization of anticoagulation/antiplatelet therapy, and informed consent. The procedure is typically performed in an operating room or endovascular suite under monitored anesthesia care or general anesthesia. Access is obtained (commonly femoral or popliteal), and the provider performs thrombectomy/endarterectomy or other mechanical removal of thrombus and plaque from the popliteal artery using appropriate instruments (e.g., Fogarty catheter, thrombectomy devices, or open surgical techniques). Completion angiography confirms restoration of flow. Post-procedure care includes monitoring in PACU or inpatient unit, vascular assessments, anticoagulation/antiplatelet management, and follow-up vascular studies.

    Typical site of service: Hospital outpatient department or Operating room/endovascular suite depending on approach and inpatient status.

    Service type: Surgical — arterial thrombectomy/endarterectomy of the popliteal artery.

    Typical patient scenario example: A 68-year-old patient with diabetes and peripheral artery disease presents with worsening right calf claudication and decreased right dorsalis pedis pulse. Duplex and CT angiography show an occlusive thrombus and atherosclerotic plaque in the right popliteal artery. The vascular surgeon schedules an urgent popliteal thrombectomy/endarterectomy with intraoperative angiography and possible patch angioplasty.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    34701Open bypass graft, femoral-popliteal, single segment, with autogenous vein; above kneeMay be performed when thrombectomy/endarterectomy is insufficient and bypass is required for revascularization.
    35831Endarterectomy, tibial-peroneal trunk and branches, with patch graftRelated arterial endarterectomy of more distal segments when disease extends beyond the popliteal artery.
    36247Endovascular mechanical thrombectomy, peripheral artery, other than carotid, with catheter(s), including radiological supervision and interpretationCommon endovascular thrombectomy technique used as an alternative or adjunct to open removal of thrombus.
    75710Angiography, extremity, unilateral, radiological supervision and interpretationOften performed as diagnostic or completion angiography during the procedure to define lesions and confirm flow restoration.

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207K00000X
    2080P0206X
    2086S0122X
    363L00000X
    207R00000X
    225CA2500X
    2471C3401X
    246QH0401X

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-35301-CAROTID-VERTEBRAL-SUBCLAVIAN-THROMBOENDARTERECTOMY

    CPT 35301: Thromboendarterectomy/Thrombectomy, Carotid/Vertebral/Subclavian

    CPT-35302-SUPERFICIAL-FEMORAL-ARTERY-THROMBECTOMY-ATHERCTOMY

    CPT 35302: Superficial Femoral Artery Thrombectomy/Endarterectomy

    CPT-35304-TIBIOPERONEAL-TRUNK-THROMBECTOMY-ENDARTERECTOMY

    CPT 35304: Tibioperoneal Trunk Thrombectomy and Plaque Removal

    CPT-35305-TIBIAL-PERONEAL-ARTERY-THROMBECTOMY-PLAQUE-REMOVAL

    CPT 35305: Thromboendarterectomy of Tibial or Peroneal Artery

    CPT-35306-ADDITIONAL-TIBIAL-PERONEAL-ARTERY-THROMBOENDARTERECTOMY

    CPT 35306: Additional Tibial or Peroneal Artery Thromboendarterectomy

    CPT-35311-THORACIC-SUBCLAVIAN-INNOMINATE-ARTERY-THROMBECTOMY-ENDARTERECTOMY

    CPT 35311: Subclavian/Innominate Artery Thrombus and Plaque Removal

    CPT-35321-AXILLARY-BRACHIAL-ARTERY-THROMBECTOMY-ENDARTERECTOMY

    CPT 35321: Axillary or Brachial Artery Thrombectomy/Endarterectomy

    CPT-35331-ABDOMINAL-AORTIC-THROMBECTOMY-ENDARTERECTOMY

    CPT 35331: Abdominal Aortic Thrombectomy/Endarterectomy

    CPT-35341-MESENTERIC-CELIAC-RENAL-ARTERY-THROMBUS-PLAQUE-REMOVAL

    CPT 35341: Thrombus/Plaque Removal, Mesenteric/Celiac/Renal Artery

    CPT-35351-ILIAC-ARTERY-THROMBUS-ENDARTERECTOMY

    CPT 35351: Iliac Artery Thrombectomy/Endarterectomy

    Showing 1–10 of 16

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

    20960
    Local incision with foreign body removal, open, soft tissue of extremity
    Occasionally used for removal of embolic material or devices from soft tissues related to the procedure (rare).
    99100Anesthesia for patient of extreme age, younger than 1 year and older than 70 (when applicable)Anesthesia add-on that may apply for elderly patients undergoing this procedure depending on payer rules.