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    OpenPayerBilling CodesThromboendarterectomy Procedures on Arteries and VeinsCPT cpt-35304-tibioperoneal-trunk-thrombectomy-endarterectomy
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    CPT 35304: Tibioperoneal Trunk Thrombectomy and Plaque Removal

    Medicare pays $1155 on average nationally for this procedure.

    CPT code 35304 describes a surgical thrombectomy and plaque removal procedure performed on the tibioperoneal trunk artery, typically classified as an arterial thromboendarterectomy/thrombectomy; the service is a peripheral arterial surgical intervention intended to restore blood flow to the lower leg and is most often performed in an operating room or procedural suite under appropriate anesthesia for vascular surgery.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 68-year-old male with peripheral arterial disease who presents with progressive rest pain and nonhealing ulcers of the foot. Noninvasive vascular testing (ABI, arterial duplex ultrasound) and angiography demonstrate an occlusive thrombus and atherosclerotic plaque localized to the tibioperoneal trunk. The vascular surgery or interventional radiology team schedules a lower-extremity arterial thrombectomy/endarterectomy. In the operating room or interventional suite the patient undergoes regional or general anesthesia. Vascular access is obtained, the affected tibioperoneal trunk is exposed or catheterized, and the provider performs mechanical thrombectomy and plaque removal from the tibioperoneal trunk. Hemostasis is achieved, distal flow is confirmed by angiography or duplex, and the patient is recovered and monitored for limb perfusion, bleeding, or access-site complications. Typical sites of service include an inpatient operating room, ambulatory surgery center, or hospital interventional radiology suite. The service type is a surgical arterial thrombectomy/endarterectomy of a lower-extremity tibial trunk artery.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    35301Thromboendarterectomy, femoral or popliteal arteryPerformed for more proximal occlusive disease; may be performed in combination when disease extends proximally.
    35311Thromboendarterectomy, tibial, peroneal, or dorsalis pedis arteryAddresses more distal tibial or pedal arteries and may be performed in addition to tibioperoneal trunk work.
    36902Endovascular revascularization, open or percutaneous, of lower extremity; transluminal balloon angioplastyCommon adjunct when angioplasty is required after thrombus/plaque removal to optimize luminal diameter.
    76010Fluoroscopic guidance for vascular procedures (percutaneous)Imaging guidance often used intra-procedurally for endovascular thrombectomy; billed when separate and allowed.
    93924Noninvasive physiologic studies of upper or lower extremity arteries; bilateral or unilateral (segmental pressures, Doppler)Used pre- and post-procedure to document perfusion and monitor outcomes.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207K00000X
    174400000X
    208VP0000X
    207L00000X
    261QM1000X
    163WN0300X
    2086S0122X
    101YA0400X

    Related ICD-10-CM Codes

    25 rows

    ICD-10-CM CodeDescription
    E11.51Type 2 diabetes mellitus with diabetic peripheral angiopathy without gangrene
    E78.5Hyperlipidemia, unspecified
    I65.22Occlusion and stenosis of left carotid artery
    I65.29Occlusion and stenosis of unspecified carotid artery
    I70.201Unspecified atherosclerosis of native arteries of extremities, right leg
    I70.211Atherosclerosis of native arteries of extremities with intermittent claudication, right leg
    I70.221Atherosclerosis of native arteries of extremities with rest pain, right leg
    I70.231Atherosclerosis of native arteries of right leg with ulceration of thigh
    I70.241Atherosclerosis of native arteries of left leg with ulceration of thigh
    I70.261Atherosclerosis of native arteries of extremities with gangrene, right leg

    Showing 1–10 of 25

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-35301-CAROTID-VERTEBRAL-SUBCLAVIAN-THROMBOENDARTERECTOMY

    CPT 35301: Thromboendarterectomy/Thrombectomy, Carotid/Vertebral/Subclavian

    CPT-35302-SUPERFICIAL-FEMORAL-ARTERY-THROMBECTOMY-ATHERCTOMY

    CPT 35302: Superficial Femoral Artery Thrombectomy/Endarterectomy

    CPT-35303-POPLITEAL-ARTERY-THROMBUS-PLAQUE-REMOVAL

    CPT 35303: Popliteal Artery Thrombectomy/Endarterectomy

    CPT-35305-TIBIAL-PERONEAL-ARTERY-THROMBECTOMY-PLAQUE-REMOVAL

    CPT 35305: Thromboendarterectomy of Tibial or Peroneal Artery

    CPT-35306-ADDITIONAL-TIBIAL-PERONEAL-ARTERY-THROMBOENDARTERECTOMY

    CPT 35306: Additional Tibial or Peroneal Artery Thromboendarterectomy

    CPT-35311-THORACIC-SUBCLAVIAN-INNOMINATE-ARTERY-THROMBECTOMY-ENDARTERECTOMY

    CPT 35311: Subclavian/Innominate Artery Thrombus and Plaque Removal

    CPT-35321-AXILLARY-BRACHIAL-ARTERY-THROMBECTOMY-ENDARTERECTOMY

    CPT 35321: Axillary or Brachial Artery Thrombectomy/Endarterectomy

    CPT-35331-ABDOMINAL-AORTIC-THROMBECTOMY-ENDARTERECTOMY

    CPT 35331: Abdominal Aortic Thrombectomy/Endarterectomy

    CPT-35341-MESENTERIC-CELIAC-RENAL-ARTERY-THROMBUS-PLAQUE-REMOVAL

    CPT 35341: Thrombus/Plaque Removal, Mesenteric/Celiac/Renal Artery

    CPT-35351-ILIAC-ARTERY-THROMBUS-ENDARTERECTOMY

    CPT 35351: Iliac Artery Thrombectomy/Endarterectomy

    Showing 1–10 of 16

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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