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    v1.0.30
    OpenPayerBilling CodesExcision Procedures on the Neck (Soft Tissues) and ThoraxCPT cpt-21556-neck-anterior-chest-muscle-mass-excision-less-than-5cm
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    CPT 21556: Excision of Intramuscular Neck/Anterior Chest Mass (<5 cm)

    Medicare pays $500 on average nationally for this procedure.

    CPT code 21556 describes the surgical excision of an abnormal mass under 5 cm located within the muscle of the neck or anterior chest, with submission of the specimen for pathologic analysis; the service is a minor surgical procedure typically performed in an outpatient surgical suite or hospital operating room and is categorized as a soft tissue (muscle) excision for diagnostic and therapeutic purposes.

    For related coverage guidance, see recent payer policy updates: Surgical Procedures, Outpatient Surgical Procedures - Site of Service, Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 52-year-old patient presents with a palpable, mobile mass deep to the platysma in the anterior neck that has slowly enlarged over several months and causes cosmetic concern and occasional discomfort. Preoperative evaluation includes focused history, physical exam, ultrasound of the neck to define size (<5 cm) and relation to surrounding structures, and discussion of risks. The procedure is an excision of an intramuscular soft tissue mass of the neck (less than 5 cm), performed in an ambulatory surgical center or outpatient hospital operating room under monitored anesthesia care or general anesthesia. The surgeon performs a skin incision, dissects through subcutaneous tissue and muscle to isolate the lesion, excises the mass intact when possible, achieves hemostasis, irrigates the wound, and closes in layered fashion. The specimen is submitted to pathology for gross and microscopic analysis. Postoperative workflow includes recovery, wound care instructions, and pathology result review with potential further oncologic workup depending on diagnosis.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    11100Biopsy of skin, subcutaneous tissue and/or mucous membrane (e.g., incisional, punch), single lesionPerformed when a smaller cutaneous or subcutaneous sample is taken for diagnosis before or instead of full excision; may precede 21556 if diagnosis uncertain.
    20220Excision of lesion of forehead, nose, ears, eyelids, etc.; simple, up to 1.0 cmRepresents analogous small soft tissue excision codes; included for cross-reference when lesions are superficial rather than intramuscular.
    88305Level IV surgical pathology, gross and microscopic examinationTypical CPT code used by pathology for microscopic examination of the excised specimen submitted from 21556.
    11042Debridement, subcutaneous tissue and muscle, first 20 sq cm or lessMay be reported when additional debridement of infected tissue involving subcutaneous tissue and muscle is required in the operative field.
    27075Excision of sacrococcygeal pilonidal cyst or sinus; simple, openExample of another anatomic-specific excision code; used for coding context when alternate site-specific excision codes are more appropriate than 21556.
    20926Excision, tumor, soft tissue of neck area (includes muscle), 5.0 cm or greaterUsed when the excised soft tissue mass is 5 cm or larger; relates by size threshold to 21556 (which is for lesions less than 5 cm).

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    58Modifier 58 (Staged or related procedure/service by the same physician during the postoperative period) indicates that a subsequent procedure performed by the same provider during the…- Use modifier 58 when the same physician/QHP performs a procedure during the postoperative/global period of an earlier procedure and the subsequent procedure is either planned or anticipated…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207L00000X
    364SP0811X
    163WX0106X
    213E00000X
    247ZC0005X
    364SP1700X
    163WC1600X
    207RA0401X

    Related ICD-10-CM Codes

    19 rows

    ICD-10-CM CodeDescription
    C41.9Malignant neoplasm of bone and articular cartilage, unspecified
    C49.0Malignant neoplasm of connective and soft tissue of head, face and neck
    D36.0Benign neoplasm of lymph nodes
    D49.2Neoplasm of unspecified behavior of bone, soft tissue, and skin
    G47.32High altitude periodic breathing
    I83.90Asymptomatic varicose veins of unspecified lower extremity
    I87.2Venous insufficiency (chronic) (peripheral)
    J38.2Nodules of vocal cords
    J38.4Edema of larynx
    L91.8Other hypertrophic disorders of the skin

    Showing 1–10 of 19

    Related Payer Policy Updates

    Specialty: General Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Surgical ProceduresUnitedHealthcare2026-09-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01

    Related Codes

    CPT-21550-SOFT-TISSUE-EXCISION-NECK-CHEST-DIAGNOSTIC-BIOPSY

    CPT 21550: Excision of Soft Tissue, Neck or Chest for Diagnosis

    CPT-21552-SUBCUTANEOUS-MASS-EXCISION-NECK-CHEST-3CM-OR-GREATER

    CPT 21552: Excision of Subcutaneous Mass, Neck or Chest, 3.0 cm or Greater

    CPT-21554-NECK-ANTERIOR-THORAX-DEEP-TUMOR-EXCISION-5CM-PLUS

    CPT 21554: Excision of Subfascial Tumor ≥5 cm, Neck or Anterior Thorax

    CPT-21555-SUBCUTANEOUS-MASS-EXCISION-NECK-CHEST

    CPT 21555: Excision of Subcutaneous Mass, Neck or Anterior Chest (<3 cm)

    CPT-21557-EXTENSIVE-SOFT-TISSUE-EXCISION-NECK-ANTERIOR-THORAX

    CPT 21557: Extensive Excision of Soft Tissue Tumor, Neck/Anterior Thorax

    CPT-21558-EXTENSIVE-EXCISION-SOFT-TISSUE-MALIGNANT-TUMOR-NECK-THORAX

    CPT 21558: Extensive Excision of Malignant Soft Tissue Tumor, Neck/Anterior Chest

    CPT-21600-PARTIAL-RIB-RESECTION

    CPT 21600: Rib Resection for Deformity or Infection

    CPT-21601-CHEST-WALL-TUMOR-EXCISION-WITH-RIB-RESECTION

    CPT 21601: Chest Wall Tumor Excision with Rib Resection

    CPT-21602-CHEST-WALL-TUMOR-RESECTION-RECONSTRUCTION-RIBS-MYOCUTANEOUS

    CPT 21602: Chest Wall Tumor Excision with Rib Reconstruction

    CPT-21603-CHEST-WALL-TUMOR-EXCISION-RECONSTRUCTION

    CPT 21603: Chest Wall Tumor Excision with Rib Reconstruction

    Showing 1–10 of 16

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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