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    v1.0.30
    OpenPayerBilling CodesExcision Procedures on the Neck (Soft Tissues) and ThoraxCPT cpt-21603-chest-wall-tumor-excision-reconstruction
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    CPT 21603: Chest Wall Tumor Excision with Rib Reconstruction

    Medicare pays $1696 on average nationally for this procedure.

    CPT code 21603 describes surgical excision of a chest wall tumor involving ribs with associated chest wall defects that are reconstructed using myocutaneous flaps and bone grafts or prosthetic rib materials, and includes excision of suspicious mediastinal lymph nodes; this represents a major surgical resection and reconstruction procedure typically performed as an inpatient or hospital-based service in an operating room setting.

    For related coverage guidance, see recent payer policy updates: Surgical Procedures, Outpatient Surgical Procedures - Site of Service, Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old patient with a biopsy-proven malignant chest wall tumor involving multiple adjacent ribs presents for definitive surgical resection. Preoperative imaging including chest CT and PET identifies tumor invasion of the rib cage and suspicious mediastinal lymph nodes. The surgical team performs en bloc excision of the chest wall tumor with partial rib resection, mediastinal lymph node excision for staging, and immediate reconstruction of the chest wall defect using myocutaneous flaps plus prosthetic rib material and bone grafting to restore structural integrity and chest wall contour. Typical workflow includes preoperative multidisciplinary planning (thoracic surgery, plastic/reconstructive surgery, anesthesia), intraoperative tumor resection and lymph node sampling, reconstructive flap harvest and fixation of prosthetic/rib grafts, postoperative chest tube management, inpatient monitoring for respiratory function and wound/flap viability, and pathology review for margin status and nodal staging. Typical site of service is an inpatient hospital operating room with postoperative admission to a surgical ward or ICU as needed. Common clinical indications include primary chest wall sarcoma, locally advanced breast cancer with chest wall invasion, or recurrent chest wall malignancy requiring structural reconstruction.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    19318Reconstructive procedures of the chest wall using local tissue (e.g., muscle flap)May be performed by plastic/reconstructive surgeon as part of chest wall reconstruction for soft tissue coverage.
    21020Excision of lesion of ribRelated when isolated rib lesions require excision; smaller rib resections may be coded separately in different settings.
    38745Lymph node excision, mediastinalPerformed when more extensive mediastinal nodal dissection is required beyond sampling; complements staging.
    51596Implantation of prosthetic material for chest wall reconstruction (note: illustrative)Used when prosthetic materials or plates are implanted for rib reconstruction; documents fixation/reconstruction.
    31500Intubation, endotracheal, emergency or plannedRelated anesthesia/airway management code relevant to perioperative care.

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207QA0505X
    207XX0005X
    207KI0005X
    3336C0004X
    237600000X
    163WM1400X
    2279P4000X
    101YM0800X

    Related ICD-10-CM Codes

    23 rows

    ICD-10-CM CodeDescription
    C34.90Malignant neoplasm of unspecified part of unspecified bronchus or lung
    C38.4Malignant neoplasm of pleura
    C41.0Malignant neoplasm of bones of skull and face
    C41.2Malignant neoplasm of vertebral column
    C45.1Mesothelioma of peritoneum
    C49.6Malignant neoplasm of connective and soft tissue of trunk, unspecified
    C50.911Malignant neoplasm of unspecified site of right female breast
    C50.919Malignant neoplasm of unspecified site of unspecified female breast
    C79.31Secondary malignant neoplasm of brain
    D16.9Benign neoplasm of bone and articular cartilage, unspecified

    Showing 1–10 of 23

    Related Payer Policy Updates

    Specialty: General Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Surgical ProceduresUnitedHealthcare2026-09-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01

    Related Codes

    CPT-21550-SOFT-TISSUE-EXCISION-NECK-CHEST-DIAGNOSTIC-BIOPSY

    CPT 21550: Excision of Soft Tissue, Neck or Chest for Diagnosis

    CPT-21552-SUBCUTANEOUS-MASS-EXCISION-NECK-CHEST-3CM-OR-GREATER

    CPT 21552: Excision of Subcutaneous Mass, Neck or Chest, 3.0 cm or Greater

    CPT-21554-NECK-ANTERIOR-THORAX-DEEP-TUMOR-EXCISION-5CM-PLUS

    CPT 21554: Excision of Subfascial Tumor ≥5 cm, Neck or Anterior Thorax

    CPT-21555-SUBCUTANEOUS-MASS-EXCISION-NECK-CHEST

    CPT 21555: Excision of Subcutaneous Mass, Neck or Anterior Chest (<3 cm)

    CPT-21556-NECK-ANTERIOR-CHEST-MUSCLE-MASS-EXCISION-LESS-THAN-5CM

    CPT 21556: Excision of Intramuscular Neck/Anterior Chest Mass (<5 cm)

    CPT-21557-EXTENSIVE-SOFT-TISSUE-EXCISION-NECK-ANTERIOR-THORAX

    CPT 21557: Extensive Excision of Soft Tissue Tumor, Neck/Anterior Thorax

    CPT-21558-EXTENSIVE-EXCISION-SOFT-TISSUE-MALIGNANT-TUMOR-NECK-THORAX

    CPT 21558: Extensive Excision of Malignant Soft Tissue Tumor, Neck/Anterior Chest

    CPT-21600-PARTIAL-RIB-RESECTION

    CPT 21600: Rib Resection for Deformity or Infection

    CPT-21601-CHEST-WALL-TUMOR-EXCISION-WITH-RIB-RESECTION

    CPT 21601: Chest Wall Tumor Excision with Rib Resection

    CPT-21602-CHEST-WALL-TUMOR-RESECTION-RECONSTRUCTION-RIBS-MYOCUTANEOUS

    CPT 21602: Chest Wall Tumor Excision with Rib Reconstruction

    Showing 1–10 of 16

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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