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    v1.0.30
    OpenPayerBilling CodesExcision Procedures on the Neck (Soft Tissues) and ThoraxCPT cpt-21555-subcutaneous-mass-excision-neck-chest
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    CPT 21555: Excision of Subcutaneous Mass, Neck or Anterior Chest (<3 cm)

    Medicare pays $477 on average nationally for this procedure.

    CPT code 21555 describes the surgical excision of a subcutaneous abnormal growth or mass less than 3 cm located in the anterior neck or chest region, with submission of the specimen for pathological analysis; this represents a minor surgical soft-tissue lesion excision procedure typically performed in an outpatient surgical suite, ambulatory surgery center, or office-based procedure room under local or general anesthesia.

    For related coverage guidance, see recent payer policy updates: Surgical Procedures, Outpatient Surgical Procedures - Site of Service, Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults.

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    Clinical & Coding Specifications

    Clinical Context

    A 42-year-old patient presents to an outpatient surgical clinic with a palpable, mobile subcutaneous mass in the anterior neck just inferior to the mandible, measuring approximately 1.8 cm on clinical exam and ultrasound. The mass is suspected to be an epidermal inclusion cyst versus benign lipoma; the provider plans a focused excision of the lesion with submission of the specimen for pathologic analysis to establish a definitive diagnosis. The procedure is performed under local anesthesia in a minor procedure room within the ambulatory surgery center. The workflow includes pre-procedure consent, localized infiltration with lidocaine with epinephrine, a 1.5–2.5 cm incision, dissection of the subcutaneous mass intact when feasible, hemostasis, layered closure, and submission of the specimen to surgical pathology. Post-procedure instructions include wound care, activity restrictions, and follow-up for pathology results and wound check. This presentation and procedure align with the elements described by 21555 (excision of a subcutaneous mass less than 3 cm from the neck or anterior chest with specimen sent for pathologic examination).

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    11102Tangential biopsy of skin (shave), single lesionMay be used when a superficial shave biopsy is performed instead of a full-thickness excision for a skin lesion prior to or instead of 21555.
    11400Excision, benign lesion including margins, trunk, arms or legs; excised diameter 0.5 cm or lessRepresents alternative skin lesion excision codes when lesion is epidermal and skin-only; selection depends on lesion depth and whether subcutaneous tissue is removed (contrast with 21555 which is subcutaneous).
    12031Repair, intermediate, wound closure of neck, 2.6 cm to 7.5 cmMay be reported when the excision requires intermediate layered closure beyond a simple closure following 21555.
    99024Postoperative follow-up visit, after discharge from facilityUsed for routine postoperative follow-up visits related to the excision when billable per payer policy.
    88305Surgical pathology, gross and microscopic examination, level IVUsed by pathology to report evaluation of submitted specimen from 21555; the exact level depends on specimen complexity.

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    24Modifier 24 denotes an unrelated evaluation and management (E/M) service performed by the same physician or qualified healthcare professional during a postoperative global period. Per CPT guidance,…- Use modifier 24 when you report an evaluation and management (E/M) service performed by the same physician or same-specialty group during a procedure’s postoperative global period that is unrelated…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207P00000X
    207L00000X
    3416S0300X
    133VN1201X
    102X00000X
    2080P1004X
    2471S1302X
    2279S1500X

    Related Payer Policy Updates

    Specialty: General Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Surgical ProceduresUnitedHealthcare2026-09-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01

    Related Codes

    CPT-21550-SOFT-TISSUE-EXCISION-NECK-CHEST-DIAGNOSTIC-BIOPSY

    CPT 21550: Excision of Soft Tissue, Neck or Chest for Diagnosis

    CPT-21552-SUBCUTANEOUS-MASS-EXCISION-NECK-CHEST-3CM-OR-GREATER

    CPT 21552: Excision of Subcutaneous Mass, Neck or Chest, 3.0 cm or Greater

    CPT-21554-NECK-ANTERIOR-THORAX-DEEP-TUMOR-EXCISION-5CM-PLUS

    CPT 21554: Excision of Subfascial Tumor ≥5 cm, Neck or Anterior Thorax

    CPT-21556-NECK-ANTERIOR-CHEST-MUSCLE-MASS-EXCISION-LESS-THAN-5CM

    CPT 21556: Excision of Intramuscular Neck/Anterior Chest Mass (<5 cm)

    CPT-21557-EXTENSIVE-SOFT-TISSUE-EXCISION-NECK-ANTERIOR-THORAX

    CPT 21557: Extensive Excision of Soft Tissue Tumor, Neck/Anterior Thorax

    CPT-21558-EXTENSIVE-EXCISION-SOFT-TISSUE-MALIGNANT-TUMOR-NECK-THORAX

    CPT 21558: Extensive Excision of Malignant Soft Tissue Tumor, Neck/Anterior Chest

    CPT-21600-PARTIAL-RIB-RESECTION

    CPT 21600: Rib Resection for Deformity or Infection

    CPT-21601-CHEST-WALL-TUMOR-EXCISION-WITH-RIB-RESECTION

    CPT 21601: Chest Wall Tumor Excision with Rib Resection

    CPT-21602-CHEST-WALL-TUMOR-RESECTION-RECONSTRUCTION-RIBS-MYOCUTANEOUS

    CPT 21602: Chest Wall Tumor Excision with Rib Reconstruction

    CPT-21603-CHEST-WALL-TUMOR-EXCISION-RECONSTRUCTION

    CPT 21603: Chest Wall Tumor Excision with Rib Reconstruction

    Showing 1–10 of 16

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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