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    v1.0.30
    OpenPayerBilling CodesIntroduction Procedures on the BreastCPT cpt-19288-mri-guided-add-on-breast-localization
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    CPT 19288: MRI-Guided Breast Localization, Add-on

    Medicare pays $478 on average nationally for this procedure.

    CPT code 19288 is an add-on MRI-guided breast localization procedure code used when an additional localization device (clip, metallic pellet, wire/needle, or radioactive seed) is placed at the same session as another device at an initial lesion; the service type is image-guided breast localization (MRI guidance) and the typical site of service is an outpatient imaging suite or breast center within a hospital or ambulatory surgical center.

    For related coverage guidance, see recent payer policy updates: Removal of Implantable, Outpatient Surgical Procedures - Site of Service, Surgical Procedures.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult woman with a known breast lesion undergoing image-guided localization prior to surgical excision. She has multiple foci or a second lesion identified on preoperative breast magnetic resonance imaging (MRI) in the same session as an initial localization. Under MRI guidance, the breast radiologist or breast surgeon places an additional localization device (for example, a clip, metallic pellet, wire/needle, or radioactive seed) at the second lesion during the same encounter when another localization device is placed at the initial lesion. The workflow includes pre-procedure review of prior imaging and indications, informed consent, MRI localization with sterile technique in the interventional MRI suite, placement and documentation of device position with confirmatory MRI images, post-procedure site care instructions, and coordination of the localization information with the surgical team for operative planning. Typical site of service is the hospital outpatient imaging department or an ambulatory surgery center with MRI-guided interventional capability.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    19283Placement of localization device(s) for directed excision, metallic clip(s), or metallic pellet(s), including imaging guidance when performed (eg, stereotactic placement, ultrasound guidance); first lesion, each lesionOften reported for the primary lesion localization; 19288 is an add-on when an additional device is placed in the same session under MRI guidance.
    19287Placement of localization device(s) for directed excision, wire/needle (eg, for breast lesion), including imaging guidance when performed; first lesion, each lesionUsed for wire localization of the initial lesion; 19288 can be used to report the additional MRI-guided device placed at the same session.
    19295Insertion of non-radioactive seed localization device for breast tumor, each lesion (note: example code—confirm payer policy)Codes for seed placement when performed; 19288 describes an add-on MRI-guided additional device and may be reported in conjunction according to payer rules.
    77021Magnetic resonance guidance for needle placement (eg, biopsy, aspiration, injection, or localization device placement), percutaneous; each additional lesionMRI guidance code often reported for MRI-directed procedures; used in the workflow for localization and image confirmation.
    76942Ultrasonic guidance for needle placement (eg, biopsy, aspiration, injection, localization device), imaging supervision and interpretationIf ultrasound guidance is used for one lesion and MRI for an additional lesion, this code may appear in the overall procedural set.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RH0000X
    208000000X
    207X00000X
    282NC2000X
    164X00000X
    261QR0800X
    1744R1102X
    2086S0102X

    Related Payer Policy Updates

    Specialty: General Surgery1 / 3

    10 rows

    PolicyPayerEffective Date
    Removal of ImplantableBlue Cross Blue Shield - Rhode Island2026-10-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Surgical ProceduresUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Medical Necessity Guidelines Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01

    Related Codes

    CPT-19281-BREAST-LESION-LOCALIZATION-MAMMOGRAPHIC-GUIDANCE

    CPT 19281: Mammographic-Guided Breast Lesion Localization, First Lesion

    CPT-19282-BREAST-LOCALIZATION-DEVICE-PLACEMENT-MAMMOGRAPHIC-GUIDANCE

    CPT 19282: Mammographic-Guided Breast Localization Add-On

    CPT-19283-STEREOTACTIC-BREAST-LESION-LOCALIZATION-FIRST-LESION

    CPT 19283: Stereotactic Breast Lesion Localization, First Lesion

    CPT-19284-STEREOTACTIC-BREAST-LOCALIZATION-ADD-ON

    CPT 19284: Stereotactic Add-On Breast Localization, Additional Lesion

    CPT-19285-BREAST-LESION-LOCALIZATION-ULTRASOUND-GUIDED-FIRST-LESION

    CPT 19285: Ultrasound-Guided Breast Lesion Localization, First Lesion

    CPT-19286-ULTRASOUND-GUIDED-BREAST-LOCALIZATION-ADD-ON

    CPT 19286: Ultrasound-Guided Breast Localization Device Placement

    CPT-19287-MRI-GUIDED-BREAST-LESION-LOCALIZATION

    CPT 19287: MRI-Guided Breast Lesion Localization, First Lesion

    CPT-19294-TUMOR-CAVITY-PREPARATION-IORT-PARTIAL-MASTECTOMY

    CPT 19294: Tumor Cavity Preparation for Intraoperative Radiation Therapy

    CPT-19296-BALLOON-CATHETER-PLACEMENT-BRACHYTHERAPY-PARTIAL-MASTECTOMY

    CPT 19296: Balloon Catheter Placement for Breast Radiotherapy After Partial Mastectomy

    CPT-19297-BALLOON-CATHETER-PLACEMENT-PARTIAL-MASTECTOMY-RADIOTHERAPY

    CPT 19297: Balloon Catheter Placement for Radiotherapy at Partial Mastectomy

    Showing 1–10 of 11

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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