Loading...

    Explore
    • Policy Monitoring
    • Live Policy Feed
    • Billing Codes
    • NPI Medicare & Medicaid
    • Healthcare Providers
    • Health Insurance Payers
    • States
    • Service Lines
    • Taxonomy Codes
    Lookup tools
    • Billing Code Lookup
    • CPT Modifier Lookup
    • Provider Taxonomy Code Lookup
    • Healthcare Provider & Facility Lookup
    • Health Insurance Payer Lookup
    • Payer Contact Directory

    Policy & Benchmark Tools

    • Prior Authorization Lookup
    • Coverage Criteria Lookup
    • Timely Filing Lookup
    • Billing Code Reimbursement Rates
    • Payer Comparison Dashboard
    • Facility Comparison Dashboard
    • All tools

    Company

    • About OpenPayer
    • Data Sources
    • Trek Health
    OpenPayerby Trek Health
    LinkedInYouTube

    © 2026 Trek Health. All rights reserved.

    OpenPayer is built and maintained by Trek Health.

    v1.0.28
    OpenPayerBilling CodesDiseases and Disorders of the Hepatobiliary System and PancreasDRG 441-disorders-of-liver-except-malignancy-cirrhosis-or-alcoholic-hepatitis-with-mcc
    Ask Trek AI about this page

    Disorders of Liver Except Malignancy, Cirrhosis or Alcoholic Hepatitis with MCC: Inpatient Reimbursement Overview

    DRG 441 addresses nonmalignant liver disorders (excluding cirrhosis and alcoholic hepatitis) with a Major Complication or Comorbidity and captures higher-severity inpatient medical complexity. It matters for inpatient reimbursement because the Major Complication or Comorbidity elevates resource intensity and influences Centers for Medicare & Medicaid Services payment determinations.

    Customize your policy alerts

    Sign up for drg 441 policy alerts

    Get alerted when payer policies referencing 441 are released or updated.

    Monitor payer policy activity

    Receive email alerts as soon as relevant payer policies are published or updated.

    DRG 441 Overview

    DRG 441 covers hospitalizations for nonmalignant liver disorders excluding cirrhosis and alcoholic hepatitis when a Major Complication or Comorbidity is present. Typical cases include acute or chronic liver diseases with severe physiological disturbances that require higher-intensity inpatient resources. This Diagnosis-Related Group matters for Medicare payment because presence of a Major Complication or Comorbidity raises the relative resource weight and impacts reimbursement. Accurate coding of comorbid conditions and primary diagnoses directly affects case grouping and payment under Centers for Medicare & Medicaid Services rules.

    Table of contents

    Progress1 / 3

    Explore openpayer tools

    • Billing CodesCPT, HCPCS, DRG & more
    • Reimbursement RatesCommercial vs. Medicare rate reports
    • ProvidersHospitals & facilities
    • PayersPlans & market footprint
    • Taxonomy CodesNUCC specialty codes
    • ModifiersCPT modifiers & usage
    • Prior AuthorizationPA policies by payer & drug
    • Timely FilingFiling deadlines by payer
    • Coverage CriteriaMedical necessity by payer
    • Payer ContactsClaims, PA & appeals contacts
    View all tools

    Clinical Trials

    • Acute management and complication prevention trials: Studies in this area evaluate early interventions during hospital admission for non-malignant liver disorders (such as fulminant hepatic failure, severe steatohepatitis flares, acute viral or drug-induced liver injury) that carry major complication codes (MCC). Patient populations are acutely ill inpatients with organ dysfunction (hepatic encephalopathy, coagulopathy, renal impairment) and trials test strategies like optimized critical-care protocols, extracorporeal liver support use, or protocolized management bundles to reduce progression to multi-organ failure. These trials are relevant to providers for guiding evidence-based inpatient protocols and to payers because effective acute interventions can shorten length of stay, reduce ICU utilization, and prevent costly downstream complications.
    • Comparative effectiveness and care pathway studies for comorbidity management: This research compares different approaches to managing common comorbid conditions that drive complexity in this DRG population (for example, approaches to managing portal hypertension complications, infection prophylaxis in cirrhosis-excluded chronic liver disease, or anticoagulation strategies in patients with coagulopathy). The study populations include hospitalized patients with chronic liver disease exacerbations and significant comorbidities (renal dysfunction, diabetes, cardiovascular disease) where the choice of strategy affects in-hospital morbidity and readmission risk. Findings inform clinicians on which diagnostic or therapeutic pathways yield better short-term outcomes and inform payers on which care pathways provide better value by reducing resource use and readmissions.
    • Post-discharge outcomes and transitional-care intervention trials: These studies evaluate interventions delivered near discharge or in the immediate post-discharge period (enhanced discharge planning, telemonitoring, early outpatient hepatology follow-up, structured medication reconciliation) for patients discharged after an admission for non-malignant liver disorders with major complications. The focus population is high-risk inpatients with recent organ dysfunction or frequent prior admissions, and outcomes studied include 30- and 90-day readmissions, mortality, and outpatient utilization. This research is important to providers for reducing preventable readmissions and improving continuity of care, and to payers because successful transitional interventions can lower post-discharge costs and penalties tied to readmission metrics.

    Related Codes

    405-PANCREAS-LIVER-AND-SHUNT-PROCEDURES-WITH-MCC

    Pancreas, Liver and Shunt Procedures with MCC: Inpatient Reimbursement Overview

    406-PANCREAS-LIVER-AND-SHUNT-PROCEDURES-WITH-CC

    Pancreas, Liver and Shunt Procedures with CC: Inpatient Reimbursement Overview

    407-PANCREAS-LIVER-AND-SHUNT-PROCEDURES-WITHOUT-CC-MCC

    Pancreas, Liver and Shunt Procedures without CC/MCC: Inpatient Reimbursement Overview

    408-BILIARY-TRACT-PROCEDURES-EXCEPT-ONLY-CHOLECYSTECTOMY-WITH-OR-WITHOUT-C-D-E-WITH-MCC

    Biliary Tract Procedures Except Only Cholecystectomy with or without C.D.E. with MCC: Inpatient Reimbursement Overview

    409-BILIARY-TRACT-PROCEDURES-EXCEPT-ONLY-CHOLECYSTECTOMY-WITH-OR-WITHOUT-C-D-E-WITH-CC

    Biliary Tract Procedures Except Only Cholecystectomy with or without C.D.E. with CC: Inpatient Reimbursement Overview

    410-BILIARY-TRACT-PROCEDURES-EXCEPT-ONLY-CHOLECYSTECTOMY-WITH-OR-WITHOUT-C-D-E-WITHOUT-CC-MCC

    Biliary Tract Procedures Except Only Cholecystectomy with or without C.D.E.: Inpatient Reimbursement Overview

    411-CHOLECYSTECTOMY-WITH-C-D-E-WITH-MCC

    Cholecystectomy with C.D.E. with MCC: Inpatient Reimbursement Overview

    412-CHOLECYSTECTOMY-WITH-C-D-E-WITH-CC

    Cholecystectomy with Common Duct Exploration with Complication or Comorbidity: Inpatient Reimbursement Overview

    413-CHOLECYSTECTOMY-WITH-C-D-E-WITHOUT-CC-MCC

    Cholecystectomy with C.D.E. without CC/MCC: Inpatient Reimbursement Overview

    414-CHOLECYSTECTOMY-EXCEPT-BY-LAPAROSCOPE-WITHOUT-C-D-E-WITH-MCC

    Cholecystectomy Except by Laparoscope without C.D.E. with MCC: Inpatient Reimbursement Overview

    Showing 1–10 of 35

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
    Published by

    Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.