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    v1.0.30
    OpenPayerBilling CodesDiseases and Disorders of the Hepatobiliary System and PancreasDRG 411-cholecystectomy-with-c-d-e-with-mcc
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    Cholecystectomy with C.D.E. with MCC: Inpatient Reimbursement Overview

    DRG 411 addresses cholecystectomy with common bile duct exploration in the presence of a Major Complication or Comorbidity; it defines the inpatient clinical scope for these higher-acuity biliary surgeries. Correct grouping under this Diagnosis-Related Group affects Medicare reimbursement by reflecting increased resource intensity and payment weighting for complicated cases.

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    DRG 411 Overview

    DRG 411 covers inpatient admissions for cholecystectomy with common bile duct exploration when a Major Complication or Comorbidity is present. It encompasses surgical treatment of gallbladder disease combined with biliary tract procedures in patients with significant additional diagnoses that increase resource use. This Diagnosis-Related Group is important for Medicare payment because the presence of a Major Complication or Comorbidity raises the relative weight and reimbursement for higher-acuity cases. Facilities and coders use this grouping to align clinical documentation and billing with inpatient reimbursement rules.

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    Clinical Trials

    • Acute perioperative intervention trials: These studies evaluate immediate intraoperative or early postoperative interventions for patients undergoing cholecystectomy with common bile duct exploration (C.D.E.) who present with complicated gallstone disease such as acute cholecystitis, choledocholithiasis, or cholangitis. Typical objectives include assessing techniques to reduce intraoperative bile duct injury, optimal timing and method of bile duct exploration (open vs. laparoscopic vs. transcystic approaches), and strategies to minimize operative time and blood loss in high-risk surgical candidates. Findings are directly relevant to surgeons and hospital administrators because improved acute interventions can lower complication rates, shorten length of stay, and reduce the need for reoperations or readmissions, affecting inpatient reimbursement and resource utilization.
    • Comparative effectiveness and procedural strategy studies: These trials compare different management pathways for patients requiring cholecystectomy with C.D.E., such as single-stage surgical bile duct clearance at index operation versus staged management with pre- or post-operative endoscopic retrograde intervention. They often enroll heterogeneous adult populations stratified by severity (e.g., presence of sepsis, coagulopathy, prior abdominal surgery) to determine which pathway yields better stone clearance rates, fewer complications, and cost-effectiveness across subgroups. Results inform clinical decision-making and payer policy by clarifying which strategies provide the best outcomes for particular patient profiles and may influence DRG-coded resource use and bundled payment considerations.
    • Post-discharge outcomes and quality-of-care studies: These observational or interventional research projects follow patients after discharge to study readmission drivers, long-term biliary complication rates, functional recovery, and patient-reported outcomes following cholecystectomy with C.D.E., including those with major complications (MCC). They target populations at higher risk for poor recovery—older adults, patients with multiple comorbidities, or those who experienced perioperative complications—to identify predictors of prolonged recovery and effective post-acute care pathways (e.g., early outpatient follow-up, home health interventions). Insights from this research help providers and payers design discharge planning, transitional care programs, and quality metrics that reduce costly readmissions and improve value for patients assigned to this DRG.

    Related Codes

    405-PANCREAS-LIVER-AND-SHUNT-PROCEDURES-WITH-MCC

    Pancreas, Liver and Shunt Procedures with MCC: Inpatient Reimbursement Overview

    406-PANCREAS-LIVER-AND-SHUNT-PROCEDURES-WITH-CC

    Pancreas, Liver and Shunt Procedures with CC: Inpatient Reimbursement Overview

    407-PANCREAS-LIVER-AND-SHUNT-PROCEDURES-WITHOUT-CC-MCC

    Pancreas, Liver and Shunt Procedures without CC/MCC: Inpatient Reimbursement Overview

    408-BILIARY-TRACT-PROCEDURES-EXCEPT-ONLY-CHOLECYSTECTOMY-WITH-OR-WITHOUT-C-D-E-WITH-MCC

    Biliary Tract Procedures Except Only Cholecystectomy with or without C.D.E. with MCC: Inpatient Reimbursement Overview

    409-BILIARY-TRACT-PROCEDURES-EXCEPT-ONLY-CHOLECYSTECTOMY-WITH-OR-WITHOUT-C-D-E-WITH-CC

    Biliary Tract Procedures Except Only Cholecystectomy with or without C.D.E. with CC: Inpatient Reimbursement Overview

    410-BILIARY-TRACT-PROCEDURES-EXCEPT-ONLY-CHOLECYSTECTOMY-WITH-OR-WITHOUT-C-D-E-WITHOUT-CC-MCC

    Biliary Tract Procedures Except Only Cholecystectomy with or without C.D.E.: Inpatient Reimbursement Overview

    412-CHOLECYSTECTOMY-WITH-C-D-E-WITH-CC

    Cholecystectomy with Common Duct Exploration with Complication or Comorbidity: Inpatient Reimbursement Overview

    413-CHOLECYSTECTOMY-WITH-C-D-E-WITHOUT-CC-MCC

    Cholecystectomy with C.D.E. without CC/MCC: Inpatient Reimbursement Overview

    414-CHOLECYSTECTOMY-EXCEPT-BY-LAPAROSCOPE-WITHOUT-C-D-E-WITH-MCC

    Cholecystectomy Except by Laparoscope without C.D.E. with MCC: Inpatient Reimbursement Overview

    415-CHOLECYSTECTOMY-EXCEPT-BY-LAPAROSCOPE-WITHOUT-C-D-E-WITH-CC

    Cholecystectomy Except by Laparoscope without C.D.E. with CC: Inpatient Reimbursement Overview

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    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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