ICD-10-PCS Code For Pancreatic Duct: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group 0F5D includes procedures performed to destroy tissue in the pancreatic duct of the hepatobiliary system and pancreas. These ICD-10-PCS codes are used for inpatient documentation when a clinician intentionally eradicates all or a portion of the pancreatic duct using energy, force, or a destructive agent to treat disease. Accurate coding within the ICD-10-PCS 0F5D group is essential for proper inpatient reimbursement, as it captures the procedure performed and the specific anatomic site treated, supporting appropriate case mix and payment.

Customize your policy alerts

Sign up for ICD-10-PCS Code For Pancreatic Duct: Procedure Code Group Overview policy alerts

Get alerted when relevant policies change without checking for updates manually.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

Pancreatic Duct Destruction Procedure Overview

This procedure group includes destruction of all or a portion of the pancreatic duct within the hepatobiliary system and pancreas. Procedures use energy, force, or a destructive agent directly applied to the pancreatic duct to eradicate tissue. Accurate coding of these destruction procedures is important for inpatient documentation and reimbursement because it captures the specific root operation and anatomic site treated, which affects case mix and payment determination.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
0	Section	Medical and Surgical
F	Body System	Hepatobiliary System and Pancreas
5	Operation	Destruction
D	Body Part	Pancreatic Duct

Explore openpayer tools

View all tools

ICD-10-PCS Code For Pancreatic Duct: Procedure Code Group Overview

Customize your policy alerts

Sign up for ICD-10-PCS Code For Pancreatic Duct: Procedure Code Group Overview policy alerts

Get alerted when relevant policies change without checking for updates manually.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

Pancreatic Duct Destruction Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
0	Section	Medical and Surgical
F	Body System	Hepatobiliary System and Pancreas
5	Operation	Destruction
D	Body Part	Pancreatic Duct

When to Use

Use a code from this group when a procedure intentionally destroys tissue of the pancreatic duct as the primary objective of the inpatient operation. Do not use these codes for incidental damage; they are for documented intentional eradication of all or a portion of the pancreatic duct.

ICD-10-PCS Codes

8 rows

ICD-10-PCS Code	Description
0F5D0Z3	Destruction of Pancreatic Duct using Laser Interstitial Thermal Therapy, Open Approach
0F5D0ZZ	Destruction of Pancreatic Duct, Open Approach
0F5D3Z3	Destruction of Pancreatic Duct using Laser Interstitial Thermal Therapy, Percutaneous Approach
0F5D3ZZ	Destruction of Pancreatic Duct, Percutaneous Approach
0F5D4Z3	Destruction of Pancreatic Duct using Laser Interstitial Thermal Therapy, Percutaneous Endoscopic Approach
0F5D4ZZ	Destruction of Pancreatic Duct, Percutaneous Endoscopic Approach
0F5D7ZZ	Destruction of Pancreatic Duct, Via Natural or Artificial Opening
0F5D8ZZ	Destruction of Pancreatic Duct, Via Natural or Artificial Opening Endoscopic

DRG Codes

9 rows

DRG Code	Description
405	Pancreas, Liver and Shunt Procedures with MCC
406	Pancreas, Liver and Shunt Procedures with CC
407	Pancreas, Liver and Shunt Procedures without CC/MCC
628	Other Endocrine, Nutritional and Metabolic O.R. Procedures with MCC
629	Other Endocrine, Nutritional and Metabolic O.R. Procedures with CC
630	Other Endocrine, Nutritional and Metabolic O.R. Procedures without CC/MCC
987	Non-Extensive O.R. Procedures Unrelated to Principal Diagnosis with MCC
988	Non-Extensive O.R. Procedures Unrelated to Principal Diagnosis with CC
989	Non-Extensive O.R. Procedures Unrelated to Principal Diagnosis without CC/MCC

Typical Clinical Scenarios

A 62-year-old patient with known intraductal papillary mucinous neoplasm (IPMN) of the main pancreatic duct presents for a planned operative procedure to eradicate dysplastic ductal epithelium localized to a segment of the pancreatic duct. The surgeon performs open-access direct destruction of the affected duct segment using a focused laser interstitial thermal therapy device to ablate the lesion while preserving surrounding pancreatic parenchyma. This elective, organ-preserving approach is undertaken to remove the premalignant tissue when resection is not indicated or is high-risk. Typical codes: 0F5D0Z3
A 48-year-old patient presents emergently with severe recurrent pancreatitis due to an obstructing ductal stricture and persistent ductal leaks after failed endoscopic stenting. Percutaneous image-guided access to the pancreatic duct is obtained and targeted destructive therapy is applied to the diseased ductal segment using percutaneous laser interstitial thermal therapy to obliterate the source of persistent leakage and inflammation. The percutaneous destructive procedure is performed to control ongoing sepsis risk and halt further ductal injury. Typical codes: 0F5D3Z3
A patient with prior endoscopic interventions for chronic pancreatitis continues to have symptomatic ductal stricture and recurrent pain despite prior therapies; during a subsequent endoscopic session the clinician intentionally destroys the affected ductal tissue via a percutaneous endoscopic approach without using a specific device beyond direct cauterizing/destructive technique. The procedure targets the pancreatic duct to ablate scarred tissue contributing to obstruction as a revision attempt after prior treatments failed. Typical codes: 0F5D4ZZ

Related Codes

0F50-LIVER-DESTRUCTION

ICD-10-PCS Code For Liver: Procedure Code Group Overview

0F51-LIVER-RIGHT-LOBE-DESTRUCTION

ICD-10-PCS Code For Liver Right Lobe: Procedure Code Group Overview

0F52-LEFT-LOBE-DESTRUCTION

ICD-10-PCS Code For Liver Left Lobe: Procedure Code Group Overview

0F54-GALLBLADDER-DESTRUCTION

ICD-10-PCS Code For Gallbladder: Procedure Code Group Overview

0F55-HEPATIC-DUCT-RIGHT-DESTRUCTION

ICD-10-PCS Code For Hepatic Duct Right: Procedure Code Group Overview

0F56-LEFT-HEPATIC-DUCT-DESTRUCTION

ICD-10-PCS Code For Hepatic Duct, Left: Procedure Code Group Overview

0F57-HEPATIC-DUCT-COMMON-DESTRUCTION

ICD-10-PCS Code For Hepatic Duct Common: Procedure Code Group Overview

0F58-CYSTIC-DUCT-DESTRUCTION

ICD-10-PCS Code For Cystic Duct: Procedure Code Group Overview

0F59-COMMON-BILE-DUCT-DESTRUCTION

ICD-10-PCS Code For Common Bile Duct: Procedure Code Group Overview

0F5C-AMPULLA-OF-VATER-DESTRUCTION

ICD-10-PCS Code For Ampulla Of Vater: Procedure Code Group Overview

Showing 1–10 of 12

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

Explore openpayer tools

View all tools

When to Use

ICD-10-PCS Codes

8 rows

ICD-10-PCS Code	Description
0F5D0Z3	Destruction of Pancreatic Duct using Laser Interstitial Thermal Therapy, Open Approach
0F5D0ZZ	Destruction of Pancreatic Duct, Open Approach
0F5D3Z3	Destruction of Pancreatic Duct using Laser Interstitial Thermal Therapy, Percutaneous Approach
0F5D3ZZ	Destruction of Pancreatic Duct, Percutaneous Approach
0F5D4Z3	Destruction of Pancreatic Duct using Laser Interstitial Thermal Therapy, Percutaneous Endoscopic Approach
0F5D4ZZ	Destruction of Pancreatic Duct, Percutaneous Endoscopic Approach
0F5D7ZZ	Destruction of Pancreatic Duct, Via Natural or Artificial Opening
0F5D8ZZ	Destruction of Pancreatic Duct, Via Natural or Artificial Opening Endoscopic

DRG Codes

9 rows

DRG Code	Description
405	Pancreas, Liver and Shunt Procedures with MCC
406	Pancreas, Liver and Shunt Procedures with CC
407	Pancreas, Liver and Shunt Procedures without CC/MCC
628	Other Endocrine, Nutritional and Metabolic O.R. Procedures with MCC
629	Other Endocrine, Nutritional and Metabolic O.R. Procedures with CC
630	Other Endocrine, Nutritional and Metabolic O.R. Procedures without CC/MCC
987	Non-Extensive O.R. Procedures Unrelated to Principal Diagnosis with MCC
988	Non-Extensive O.R. Procedures Unrelated to Principal Diagnosis with CC
989	Non-Extensive O.R. Procedures Unrelated to Principal Diagnosis without CC/MCC

Typical Clinical Scenarios

A 62-year-old patient with known intraductal papillary mucinous neoplasm (IPMN) of the main pancreatic duct presents for a planned operative procedure to eradicate dysplastic ductal epithelium localized to a segment of the pancreatic duct. The surgeon performs open-access direct destruction of the affected duct segment using a focused laser interstitial thermal therapy device to ablate the lesion while preserving surrounding pancreatic parenchyma. This elective, organ-preserving approach is undertaken to remove the premalignant tissue when resection is not indicated or is high-risk. Typical codes: 0F5D0Z3
A 48-year-old patient presents emergently with severe recurrent pancreatitis due to an obstructing ductal stricture and persistent ductal leaks after failed endoscopic stenting. Percutaneous image-guided access to the pancreatic duct is obtained and targeted destructive therapy is applied to the diseased ductal segment using percutaneous laser interstitial thermal therapy to obliterate the source of persistent leakage and inflammation. The percutaneous destructive procedure is performed to control ongoing sepsis risk and halt further ductal injury. Typical codes: 0F5D3Z3
A patient with prior endoscopic interventions for chronic pancreatitis continues to have symptomatic ductal stricture and recurrent pain despite prior therapies; during a subsequent endoscopic session the clinician intentionally destroys the affected ductal tissue via a percutaneous endoscopic approach without using a specific device beyond direct cauterizing/destructive technique. The procedure targets the pancreatic duct to ablate scarred tissue contributing to obstruction as a revision attempt after prior treatments failed. Typical codes: 0F5D4ZZ

Related Codes

0F50-LIVER-DESTRUCTION

ICD-10-PCS Code For Liver: Procedure Code Group Overview

0F51-LIVER-RIGHT-LOBE-DESTRUCTION

ICD-10-PCS Code For Liver Right Lobe: Procedure Code Group Overview

0F52-LEFT-LOBE-DESTRUCTION

ICD-10-PCS Code For Liver Left Lobe: Procedure Code Group Overview

0F54-GALLBLADDER-DESTRUCTION

ICD-10-PCS Code For Gallbladder: Procedure Code Group Overview

0F55-HEPATIC-DUCT-RIGHT-DESTRUCTION

ICD-10-PCS Code For Hepatic Duct Right: Procedure Code Group Overview

0F56-LEFT-HEPATIC-DUCT-DESTRUCTION

ICD-10-PCS Code For Hepatic Duct, Left: Procedure Code Group Overview

0F57-HEPATIC-DUCT-COMMON-DESTRUCTION

ICD-10-PCS Code For Hepatic Duct Common: Procedure Code Group Overview

0F58-CYSTIC-DUCT-DESTRUCTION

ICD-10-PCS Code For Cystic Duct: Procedure Code Group Overview

0F59-COMMON-BILE-DUCT-DESTRUCTION

ICD-10-PCS Code For Common Bile Duct: Procedure Code Group Overview

0F5C-AMPULLA-OF-VATER-DESTRUCTION

ICD-10-PCS Code For Ampulla Of Vater: Procedure Code Group Overview

Showing 1–10 of 12

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-PCS Code For Pancreatic Duct: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Pancreatic Duct: Procedure Code Group Overview policy alerts

Pancreatic Duct Destruction Procedure Overview

Code Attributes

ICD-10-PCS Code For Pancreatic Duct: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Pancreatic Duct: Procedure Code Group Overview policy alerts

Pancreatic Duct Destruction Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS code group covers destruction procedures of the pancreatic duct?

What are the root operation and body system attributes for codes in the 0F5D group?

Which specific ICD-10-PCS codes represent percutaneous approaches in this group?

How does accurate coding within the 0F5D group affect inpatient reimbursement?

Which DRGs may be related to procedures coded from the 0F5D group?

References

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS code group covers destruction procedures of the pancreatic duct?

What are the root operation and body system attributes for codes in the 0F5D group?

Which specific ICD-10-PCS codes represent percutaneous approaches in this group?

How does accurate coding within the 0F5D group affect inpatient reimbursement?

Which DRGs may be related to procedures coded from the 0F5D group?

References