Prior Authorization and Notification List — Humana Dual Highly Integrated South Carolina
This document lists services that require prior authorization or notification for Humana Dual Highly Integrated South Carolina members and explains how providers must request approvals and notifications. It affects providers delivering services to Humana Dual Highly Integrated South Carolina enrollees, including delegated networks and IPAs.
No material clinical or coverage changes in this revision.
Services Requiring Prior Authorization or Notification
General coverage stance
Services listed require prior authorization before being provided and must meet Medicare coverage guidelines and medical necessity. CMS timeliness rules apply for certain requests.
Inpatient admissions
All inpatient admissions require prior authorization.
Imaging and nuclear medicine
Diagnostic and cardiac imaging services listed are managed by Cohere Health and require submission to Cohere Health as indicated (prior authorization or notification).
Home health/home infusion
Home health and home infusion services listed require prior authorization and are managed by One Home Care.
Durable medical equipment
Selected durable medical equipment (DME) items require prior authorization as indicated.
Prior authorization/notification requirements (partial)
The following services require prior authorization or notification as indicated; several service groups are managed by third‑party vendors (Cohere Health, Evolent) with submission channels provided.
Examples of services requiring authorization/notification
- Observation services — notification required for all Observation services (codes = All).
- Orthopedic hip, knee and shoulder arthroplasty — managed by Cohere Health; submit authorization requests to Cohere Health (codes listed in the document).
- Orthopedic hip, knee and shoulder arthroscopy — managed by Cohere Health; submit authorization requests to Cohere Health (codes listed in the document).
- Pain infusion pump services — managed by Cohere Health; submit authorization requests to Cohere Health (codes listed in the document).
- Prostate surgeries (prostatectomy) — prior authorization managed by Evolent (formerly New Century Health); submit requests via Evolent website, phone 844-926-4528 (option 5) or eFax as provided.
- Radiation therapy — prior authorization managed by Evolent; submit via Evolent website, phone or eFax (codes listed in the document).
Authorization and notification criteria (partial)
This section lists additional services and codes requiring prior authorization or notification; several are managed by Cohere Health and specific exemptions/notification-only items are noted.
Cohere Health-managed spine and neuro services
Procedure, CPT, HCPCS and Other Code Lists
| Up to 10 procedure codes per authorization request |
| 19120 | Partial mastectomy (treatment of breast cancer) |
| 19125 | Excision of breast lesion; open, including axillary node sampling |
| 19300 | Mastectomy, simple, complete |
| 19301 | Mastectomy, partial (e.g., lumpectomy, tylectomy, quadrantectomy) |
| 19302 | Mastectomy, partial, with axillary node dissection |
| 19303 | Mastectomy, subcutaneous |
| 19316 | Mastectomy for gynecomastia, simple |
| 19317 | Mastectomy for gynecomastia, unilateral |
| 19318 | Mastectomy for gynecomastia, bilateral |
| 19325 | Breast reconstruction, immediate or delayed, with prosthesis |
| 33206-33275 | Transvenous lead/device implantation, CRT and related cardiac device procedures (inclusive range) |
| 33285-33286 | Leadless pacemaker procedures |
| 33240-33244 | Atrial lead procedures |
| 33262-33264 | Device interrogation/analysis monitoring codes |
| 33289 | Removal of leadless pacemaker |
| 33340 | Transcatheter aortic valve replacement (TAVR) — transcatheter valve procedures |
| 33361-33366 | Transcatheter mitral and other valve procedures (TMVR/TMVR-related) |
| 93264 | External mobile cardiovascular telemetry with retrospective analysis |
| C1605 | HCPCS device code (cardiac) |
| C1721-C1722 | HCPCS cardiac device codes |
| 38225-38228 | Apheresis/collection and related cellular therapy services (range) |
| 38999 | Unlisted procedure, vascular system (used for certain cell therapies) |
| 60699 | Unlisted cranial procedure (used as placeholder) |
| C9399 | Unclassified drug code (cellular therapy) |
| J3387 | CAR T-cell therapy product code |
| J3389 | CAR T or related biologic |
| J3391-J3394 | Supportive/administered CAR T agents (range) |
| J3402 | Immune/biologic agent |
| J3490 | Unclassified drugs (used for certain cell therapy drugs) |
| J3590 | Unclassified biologics |
| 70460-70498 | CT head/neck/brain ranges (notification required for specified CTs listed) |
| 70540-70553 | MRI brain/brain stem/with various sequences (notification required) |
| 73218-73220 | MRI upper extremity (notification required) |
| 73718-73720 | MRI lower extremity (notification required) |
| 70496,70498 | Additional CT codes listed in policy excerpts |
| 75572-75574 | Cardiac CT/CTA codes (notification required) |
| 78451-78494 | Myocardial perfusion imaging / nuclear cardiology (MPI) codes — notification/authorization per list |
| 78429-78433 | PET-related nuclear oncology codes (notification required) |
| 78811-78816 | PET/CT and PET imaging codes |
| 71260-71275 | CT chest codes (ranges included in imaging list) |
| 72126-72194 | CT/MRI spine/pelvis ranges |
| 73206 | MRI upper extremity general code |
| 73706 | MRI lower extremity general code |
| 74160-74178 | CT/MRI abdomen/pelvis ranges |
| 75572-75574 | Cardiac CT codes |
| C8900-C8936 | Various device/implant HCPCS codes used in imaging & cardiac lists |
| 78429-78433 | PET radiopharmaceutical procedures (range) |
| 78451-78494 | Myocardial perfusion SPECT/PET codes and related nuclear cardiology |
| 81105 | BRCA1/BRCA2 and other hereditary cancer panel examples (listed) |
| 81200-81479 | Multiple molecular diagnostic CPT codes and ranges included (selected examples) |
| 0020M, 005U, 0009U, 0018U, 0026U, 0029U, 0037U, 0045U, 0079U... | Multiple U-codes for molecular/genetic tests — examples included in list |
| 83080 | Hemoglobin A1c (listed among lab examples) |
| A2001-A2037 | Skin substitute product codes (range) |
| L8600 | Breast/implantable device-related HCPCS (also listed) |
| C1789 | Device/supply HCPCS appearing in substitute lists |
| Q2041-Q2058 | Selected Q-codes for biologic products and supplies (range) |
| C1832, C8002, C9354, C9358, C9360-C9364 | Miscellaneous product HCPCS codes listed |
How to Request Authorizations, Notifications, and Vendor Routing
How to request prior authorization and notification
How to request prior authorization and notification: Prior authorization requests should be submitted online at Availity (www.availity.com; registration required) or by calling Humana's interactive voice response line at 800-523-0023. Online submissions are encouraged; for certain services on the PAL, Availity Essentials™ may present a questionnaire which can support real-time approval or speed review. Provide all relevant clinical information with the initial submission to support timely adjudication. For vendor-managed categories (see vendor-specific callouts below), follow the vendor submission channels listed for Cohere, Evolent, and One Home Care.
- Online: www.availity.com (registration required)
- Phone: Humana IVR 800-523-0023
- Availity Essentials™ questionnaires may enable real‑time approvals
- Submit complete clinical documentation with the initial request
Timeliness requirement (CMS)
Timeliness requirement (CMS): Effective January 1, 2026, CMS requires that prior authorization decisions for certain medical items and services be made within 7 calendar days. Submit all supporting clinical information with the initial request to help ensure timely adjudication. If Humana requires additional information, a representative will contact the requester; failure to provide necessary information may delay or adversely affect the decision. Adherence to this process should begin immediately.
- CMS rule effective 2026-01-01: decision within 7 days for certain items/services
- Provide supporting clinical information at submission to avoid delays
Urgent/emergent services and risk of noncompliance
Urgent/emergent services: Urgent and emergent services do not require prior authorization or referrals. However, failure to obtain required prior authorization or provide required notification for non-urgent services may result in retrospective medical necessity review and potential financial penalties for the provider or reduced benefits for the member. Providers are advised to verify benefits and authorization/notification requirements with Humana before providing non-urgent services.
- Urgent/emergent services do not require prior authorization
- Services without required prior authorization/notification may be subject to retrospective review and financial penalties
Information required for a prior authorization request or notification
Required information for requests: Include member identifiers and visit details and attach relevant clinical documentation when submitting a prior authorization request or notification. Typical required items include the member's Humana ID, name, DOB, date(s) of service or admission, procedure codes (up to 10 per request), diagnosis codes (up to 6 per request), service location, provider TIN and NPI, caller contact, attending physician contact, relevant clinical information, and discharge plans when applicable.
- Member Humana ID, name, date of birth
- Date of actual service or hospital admission (or proposed procedure date)
- Procedure codes (up to 10) and diagnosis codes (up to 6)
- Service location and referral type
- TIN and NPI of facility and performing provider
- Caller/requestor name and telephone number; attending physician contact
- Relevant clinical documentation and discharge plans
Cohere Health-managed diagnostic/cardiac imaging prior authorization
Cohere Health-managed diagnostic and cardiac imaging: Many diagnostic and cardiac imaging services (including specified CT and MRI codes, myocardial perfusion studies, nuclear imaging, PET, SPECT, TEE, coronary and peripheral angiography, and cardiac device procedures) are managed by Cohere Health. Submit authorization requests through the Cohere Health portal, by phone at 833-283-0033 (Mon–Fri, 8 a.m.–8 p.m. ET), or by fax to 857-557-6787. Expedited/urgent cases can be submitted and monitored via the Cohere portal. If you have questions, call Cohere Health at 833-283-0033.
- Cohere portal for prior authorization requests
- Phone: 833-283-0033, Monday–Friday, 8 a.m.–8 p.m. ET
- Fax: 857-557-6787
- Expedited/urgent cases may be submitted and monitored on the Cohere portal
- Notification is required for CT/MRI codes listed (e.g., 70460–70498, 70540–70553, 73218–73220, 73718–73720)
Evolent-managed lung biopsy and resection prior authorization
Evolent-managed lung biopsy and resection: Lung biopsy and resection procedures are managed by Evolent (formerly New Century Health). Submit prior authorization requests via Evolent's website. Additional submission channels include calling Evolent at 844-926-4528 (option 5 for surgical services), Monday–Friday, 8 a.m.–8 p.m. ET, or eFax to 213-596-3783 (or eFax via email to efax-carepro-oncology@newcenturyhealth.com) when applicable.
- Evolent website submission
- Phone: 844-926-4528, option 5 (Mon–Fri, 8 a.m.–8 p.m. ET)
- eFax: 213-596-3783 or efax-carepro-oncology@newcenturyhealth.com
One Home Care-managed home health/home infusion
One Home Care-managed home health and home infusion: Home health and home infusion services require prior authorization and are managed by One Home Care. Submit authorization requests through the channels directed by One Home Care and include the applicable HCPCS/T codes listed on the PAL when requesting authorization.
Observation notification
Observation notification: Notification to Humana is required for all Observation services. Notification (not prior authorization) must be submitted for any observation encounter so Humana can coordinate care; Humana does not issue an approval or denial for notifications.
- Notification required for all Observation services (codes: All)
- Observation is a notification-only requirement (not a prior authorization)
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