HCPCS Level II E0481: Intrapulmonary Percussive Ventilation System and Accessories

HCPCS Level II code E0481 represents an intrapulmonary percussive ventilation system and related accessories used to deliver percussive respiratory therapy; the service is durable medical equipment (DME) providing airway clearance and ventilatory support typically used in outpatient, home health, or long-term care settings where mechanical respiratory support or secretion mobilization is needed.

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HCPCS Level II E0481: Intrapulmonary Percussive Ventilation System and Accessories

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Get alerted when payer policies referencing E0481 are released or updated.

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Clinical & Coding Specifications

Clinical Context

A typical patient is an adult with chronic respiratory insufficiency, bronchiectasis, neuromuscular weakness, or mucus clearance impairment who requires airway clearance therapy to mobilize secretions. A respiratory therapist or trained home health clinician evaluates the patient in the outpatient pulmonary clinic or during a home health visit. The intrapulmonary percussive ventilation system (E0481) is provided as durable medical equipment with related accessories and set up by the clinician. Treatment includes device instruction, mask/mouthpiece fitting, titration of percussion frequency and pressure, and a supervised trial to confirm tolerance and effective secretion mobilization. Follow-up includes patient education on device maintenance, troubleshooting, and a plan for ongoing use as part of pulmonary hygiene. Typical sites of service are outpatient clinics, hospital outpatient departments, skilled nursing facilities, and patient homes when provided via home health or DME delivery.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`94640`	Pressurized or nonpressurized inhalation treatment for acute airway obstruction or for sputum induction for diagnostic purposes (e.g., with nebulizer, metered-dose inhaler)	Often performed before or during initiation of airway-clearance therapy to deliver bronchodilator or mucolytic agents that facilitate percussive ventilation effectiveness
`94762`	Noninvasive cardiopulmonary ventilation (e.g., CPAP, BiPAP) initiation and management, hospital or facility	May be used in patients who require concurrent noninvasive ventilatory support when intrapulmonary percussive ventilation is integrated into care
`92526`	Treatment of swallowing dysfunction; therapeutic services to improve dysphagia	Frequently part of multidisciplinary care where secretion management and airway clearance intersect with swallowing dysfunction assessment and therapy
`94010`	Spirometry, including graphic record, total and timed vital capacity, expiratory flow rate measurement(s), with or without maximal voluntary ventilation	Baseline and follow-up pulmonary function assessment associated with respiratory device therapy
`99501`	Home visit for evaluation and management of home care plan (not a standard CPT for all payors)	Represents home-based clinical evaluation and device training visits often performed around DME delivery

Related Modifiers

5 rows

Modifier	Description	When to Use
22	Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…	- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
56	Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…	- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
62	Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…	- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
213ES0000X	Sports Medicine Podiatrist	Podiatric Medicine & Surgery Service Providers · Podiatrist
3140N1450X	Pediatric Skilled Nursing Facility	A nursing care facility designed and staffed for the provision of nursing care and appropriate educational and habilitative/rehabilitative services to…
207V00000X	Obstetrics & Gynecology Physician	An obstetrician/gynecologist possesses special knowledge, skills and professional capability in the medical and surgical care of the female reproducti…
282J00000X	Religious Nonmedical Health Care Institution	Furnishes only nonmedical nursing items and services to patients who choose to rely solely upon a religious method of healing, and for whom the accept…
207LA0401X	Addiction Medicine (Anesthesiology) Physician	An anesthesiologist who specializes in the diagnosis and treatment of addictions.
103TE1100X	Exercise & Sports Psychologist	A psychologist with a proficiency in sports psychology that uses psychological knowledge and skills to address optimal performance and well-being of a…
207NS0135X	Procedural Dermatology Physician	Procedural Dermatology, a subspecialty of Dermatology, encompassing a wide variety of surgical procedures and methods to remove or modify skin tissue …
2083X0100X	Occupational Medicine Physician	Occupational medicine focuses on the health of workers, including the ability to perform work; the physical, chemical, biological, and social environm…

Related ICD-10-CM Codes

28 rows

ICD-10-CM Code	Description
A48.1	Legionnaires' disease
B97.21	SARS-associated coronavirus as the cause of diseases classified elsewhere
E84.0	Cystic fibrosis with pulmonary manifestations
E84.11	Meconium ileus in cystic fibrosis
J18.9	Pneumonia, unspecified organism
J41.1	Mucopurulent chronic bronchitis
J43.9	Emphysema, unspecified
J44.1	Chronic obstructive pulmonary disease with (acute) exacerbation
J44.9	Chronic obstructive pulmonary disease, unspecified
J45.901	Unspecified asthma with (acute) exacerbation

Showing 1–10 of 28

HCPCS E0100: Cane, Adjustable or Fixed, With Tip

HCPCS-E0105-CANE-QUAD-THREE-PRONG-MOBILITY-AID

HCPCS Level II E0105: Cane, Quad or Three-Prong, Includes Tips

HCPCS-E0110-FOREARM-CRUTCHES-PAIR-DME-MOBILITY

HCPCS Level II E0110: Forearm Crutches, Pair, Complete with Tips and Handgrips

HCPCS-E0111-CRUTCH-FOREARM-DURABLE-MEDICAL-EQUIPMENT

HCPCS Level II E0111: Crutch, Forearm, With Tip and Handgrips

HCPCS-E0112-UNDERARM-WOOD-CRUTCHES-PAIR

HCPCS Level II E0112: Underarm Wooden Crutches, Pair

HCPCS-E0113-CRUTCH-UNDERARM-WOOD-ADJUSTABLE-FIXED-WITH-PAD-TIP-HANDGRIP

HCPCS Level II E0113: Crutch Underarm, Wood, Adjustable or Fixed

HCPCS-E0114-UNDERARM-CRUTCHES-PAIR-ADJUSTABLE-FIXED

HCPCS Level II E0114: Underarm (Axillary) Crutches, Adjustable or Fixed, Pair

HCPCS-E0116-UNDERARM-CRUTCH-NON-WOOD-ADJUSTABLE-FIXED

HCPCS E0116: Underarm Crutch, Non-Wood, Adjustable/Fixed with Pad

HCPCS-E0117-ARTICULATING-SPRING-ASSISTED-UNDERARM-CRUTCH

HCPCS Level II E0117: Crutch, Underarm, Articulating, Spring-Assisted

HCPCS-E0118-LOWER-LEG-PLATFORM-CRUTCH-SUBSTITUTE

HCPCS E0118: Crutch Substitute, Lower Leg Platform

Showing 1–10 of 670

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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Clinical & Coding Specifications

Clinical Context

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`94640`	Pressurized or nonpressurized inhalation treatment for acute airway obstruction or for sputum induction for diagnostic purposes (e.g., with nebulizer, metered-dose inhaler)	Often performed before or during initiation of airway-clearance therapy to deliver bronchodilator or mucolytic agents that facilitate percussive ventilation effectiveness
`94762`	Noninvasive cardiopulmonary ventilation (e.g., CPAP, BiPAP) initiation and management, hospital or facility	May be used in patients who require concurrent noninvasive ventilatory support when intrapulmonary percussive ventilation is integrated into care
`92526`	Treatment of swallowing dysfunction; therapeutic services to improve dysphagia	Frequently part of multidisciplinary care where secretion management and airway clearance intersect with swallowing dysfunction assessment and therapy
`94010`	Spirometry, including graphic record, total and timed vital capacity, expiratory flow rate measurement(s), with or without maximal voluntary ventilation	Baseline and follow-up pulmonary function assessment associated with respiratory device therapy
`99501`	Home visit for evaluation and management of home care plan (not a standard CPT for all payors)	Represents home-based clinical evaluation and device training visits often performed around DME delivery

Related Modifiers

5 rows

Modifier	Description	When to Use
22	Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…	- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
56	Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…	- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
62	Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…	- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
213ES0000X	Sports Medicine Podiatrist	Podiatric Medicine & Surgery Service Providers · Podiatrist
3140N1450X	Pediatric Skilled Nursing Facility	A nursing care facility designed and staffed for the provision of nursing care and appropriate educational and habilitative/rehabilitative services to…
207V00000X	Obstetrics & Gynecology Physician	An obstetrician/gynecologist possesses special knowledge, skills and professional capability in the medical and surgical care of the female reproducti…
282J00000X	Religious Nonmedical Health Care Institution	Furnishes only nonmedical nursing items and services to patients who choose to rely solely upon a religious method of healing, and for whom the accept…
207LA0401X	Addiction Medicine (Anesthesiology) Physician	An anesthesiologist who specializes in the diagnosis and treatment of addictions.
103TE1100X	Exercise & Sports Psychologist	A psychologist with a proficiency in sports psychology that uses psychological knowledge and skills to address optimal performance and well-being of a…
207NS0135X	Procedural Dermatology Physician	Procedural Dermatology, a subspecialty of Dermatology, encompassing a wide variety of surgical procedures and methods to remove or modify skin tissue …
2083X0100X	Occupational Medicine Physician	Occupational medicine focuses on the health of workers, including the ability to perform work; the physical, chemical, biological, and social environm…

Related ICD-10-CM Codes

28 rows

ICD-10-CM Code	Description
A48.1	Legionnaires' disease
B97.21	SARS-associated coronavirus as the cause of diseases classified elsewhere
E84.0	Cystic fibrosis with pulmonary manifestations
E84.11	Meconium ileus in cystic fibrosis
J18.9	Pneumonia, unspecified organism
J41.1	Mucopurulent chronic bronchitis
J43.9	Emphysema, unspecified
J44.1	Chronic obstructive pulmonary disease with (acute) exacerbation
J44.9	Chronic obstructive pulmonary disease, unspecified
J45.901	Unspecified asthma with (acute) exacerbation

Showing 1–10 of 28

HCPCS E0100: Cane, Adjustable or Fixed, With Tip

HCPCS-E0105-CANE-QUAD-THREE-PRONG-MOBILITY-AID

HCPCS Level II E0105: Cane, Quad or Three-Prong, Includes Tips

HCPCS-E0110-FOREARM-CRUTCHES-PAIR-DME-MOBILITY

HCPCS Level II E0110: Forearm Crutches, Pair, Complete with Tips and Handgrips

HCPCS-E0111-CRUTCH-FOREARM-DURABLE-MEDICAL-EQUIPMENT

HCPCS Level II E0111: Crutch, Forearm, With Tip and Handgrips

HCPCS-E0112-UNDERARM-WOOD-CRUTCHES-PAIR

HCPCS Level II E0112: Underarm Wooden Crutches, Pair

HCPCS-E0113-CRUTCH-UNDERARM-WOOD-ADJUSTABLE-FIXED-WITH-PAD-TIP-HANDGRIP

HCPCS Level II E0113: Crutch Underarm, Wood, Adjustable or Fixed

HCPCS-E0114-UNDERARM-CRUTCHES-PAIR-ADJUSTABLE-FIXED

HCPCS Level II E0114: Underarm (Axillary) Crutches, Adjustable or Fixed, Pair

HCPCS-E0116-UNDERARM-CRUTCH-NON-WOOD-ADJUSTABLE-FIXED

HCPCS E0116: Underarm Crutch, Non-Wood, Adjustable/Fixed with Pad

HCPCS-E0117-ARTICULATING-SPRING-ASSISTED-UNDERARM-CRUTCH

HCPCS Level II E0117: Crutch, Underarm, Articulating, Spring-Assisted

HCPCS-E0118-LOWER-LEG-PLATFORM-CRUTCH-SUBSTITUTE

HCPCS E0118: Crutch Substitute, Lower Leg Platform

Showing 1–10 of 670

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

OpenPayer

HCPCS Level II E0481: Intrapulmonary Percussive Ventilation System and Accessories

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HCPCS Level II E0481: Intrapulmonary Percussive Ventilation System and Accessories

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Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related ICD-10-CM Codes

Related Codes

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related ICD-10-CM Codes

Related Codes

References

HCPCS Level II E0481: Intrapulmonary Percussive Ventilation System and Accessories

Sign up for hcpcs E0481 policy alerts

HCPCS Level II E0481: Intrapulmonary Percussive Ventilation System and Accessories

Sign up for hcpcs E0481 policy alerts

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related ICD-10-CM Codes

Related Codes

What does HCPCS code E0481 represent and where is it typically provided?

Which patients and clinicians are typically involved when E0481 is used?

Which billing modifiers are commonly associated with claims for E0481?

Are there CPT codes commonly billed with E0481 and what is their relationship?

Which payers are covered in the analysis and does the page provide reimbursement rates or coverage rules?

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related ICD-10-CM Codes

Related Codes

What does HCPCS code E0481 represent and where is it typically provided?

Which patients and clinicians are typically involved when E0481 is used?

Which billing modifiers are commonly associated with claims for E0481?

Are there CPT codes commonly billed with E0481 and what is their relationship?

Which payers are covered in the analysis and does the page provide reimbursement rates or coverage rules?

References