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    v1.0.30
    OpenPayerBilling CodesDurable Medical EquipmentHCPCS hcpcs-e0481-intrapulmonary-percussive-ventilation-system
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    HCPCS Level II E0481: Intrapulmonary Percussive Ventilation System and Accessories

    HCPCS Level II code E0481 represents an intrapulmonary percussive ventilation system and related accessories used to deliver percussive respiratory therapy; the service is durable medical equipment (DME) providing airway clearance and ventilatory support typically used in outpatient, home health, or long-term care settings where mechanical respiratory support or secretion mobilization is needed.

    For related coverage guidance, see recent payer policy updates: Hospital Beds Corporate Medical Policy, Bone Growth Stimulators, Prior Authorization for Durable Medical Equipment (DME).

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    Table of contents

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    • Billing CodesCPT, HCPCS, DRG & more
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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult with chronic respiratory insufficiency, bronchiectasis, neuromuscular weakness, or mucus clearance impairment who requires airway clearance therapy to mobilize secretions. A respiratory therapist or trained home health clinician evaluates the patient in the outpatient pulmonary clinic or during a home health visit. The intrapulmonary percussive ventilation system (E0481) is provided as durable medical equipment with related accessories and set up by the clinician. Treatment includes device instruction, mask/mouthpiece fitting, titration of percussion frequency and pressure, and a supervised trial to confirm tolerance and effective secretion mobilization. Follow-up includes patient education on device maintenance, troubleshooting, and a plan for ongoing use as part of pulmonary hygiene. Typical sites of service are outpatient clinics, hospital outpatient departments, skilled nursing facilities, and patient homes when provided via home health or DME delivery.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    94640Pressurized or nonpressurized inhalation treatment for acute airway obstruction or for sputum induction for diagnostic purposes (e.g., with nebulizer, metered-dose inhaler)Often performed before or during initiation of airway-clearance therapy to deliver bronchodilator or mucolytic agents that facilitate percussive ventilation effectiveness
    94762Noninvasive cardiopulmonary ventilation (e.g., CPAP, BiPAP) initiation and management, hospital or facilityMay be used in patients who require concurrent noninvasive ventilatory support when intrapulmonary percussive ventilation is integrated into care
    92526Treatment of swallowing dysfunction; therapeutic services to improve dysphagiaFrequently part of multidisciplinary care where secretion management and airway clearance intersect with swallowing dysfunction assessment and therapy
    94010Spirometry, including graphic record, total and timed vital capacity, expiratory flow rate measurement(s), with or without maximal voluntary ventilationBaseline and follow-up pulmonary function assessment associated with respiratory device therapy
    99501Home visit for evaluation and management of home care plan (not a standard CPT for all payors)Represents home-based clinical evaluation and device training visits often performed around DME delivery

    Related Modifiers

    5 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    213ES0000X
    3140N1450X
    207V00000X
    282J00000X
    207LA0401X
    103TE1100X
    207NS0135X
    2083X0100X

    Related ICD-10-CM Codes

    28 rows

    ICD-10-CM CodeDescription
    A48.1Legionnaires' disease
    B97.21SARS-associated coronavirus as the cause of diseases classified elsewhere
    E84.0Cystic fibrosis with pulmonary manifestations
    E84.11Meconium ileus in cystic fibrosis
    J18.9Pneumonia, unspecified organism
    J41.1Mucopurulent chronic bronchitis
    J43.9Emphysema, unspecified
    J44.1Chronic obstructive pulmonary disease with (acute) exacerbation
    J44.9Chronic obstructive pulmonary disease, unspecified
    J45.901Unspecified asthma with (acute) exacerbation

    Showing 1–10 of 28

    Related Payer Policy Updates

    Specialty: Durable Medical Equipment (DME)1 / 3

    10 rows

    PolicyPayerEffective Date
    Hospital Beds Corporate Medical Policybcbsvermont2027-01-01
    Bone Growth StimulatorsMass General Brigham Health Plan2026-12-01
    Prior Authorization for Durable Medical Equipment (DME)Blue Cross Blue Shield - Rhode Island2026-12-01
    Patient Liftsuniverahealthcare2026-11-16
    Medical Car SeatsCareSource2026-11-01
    Non-Invasive Home Mechanical Ventilation (E0466)CareSource2026-11-01
    Digestive Enzyme Cartridgeshusky_health2026-11-01
    Hearing Aids and Assistive Listening Devices for Children Enrolled in Birth-to-Threehusky_health2026-11-01
    Home Non-Invasive Positive Pressure Ventilation (NIPPV) Devices for Respiratory Insufficiency and Failureexcellus_health_plan_inc2026-10-15
    Prior Authorization for Durable Medical Equipment (DME)Blue Cross Blue Shield - Rhode Island2026-10-01

    Related Codes

    HCPCS-E0100-CANE-DURABLE-MEDICAL-EQUIPMENT-AMBULATION

    HCPCS E0100: Cane, Adjustable or Fixed, With Tip

    HCPCS-E0105-CANE-QUAD-THREE-PRONG-MOBILITY-AID

    HCPCS Level II E0105: Cane, Quad or Three-Prong, Includes Tips

    HCPCS-E0110-FOREARM-CRUTCHES-PAIR-DME-MOBILITY

    HCPCS Level II E0110: Forearm Crutches, Pair, Complete with Tips and Handgrips

    HCPCS-E0111-CRUTCH-FOREARM-DURABLE-MEDICAL-EQUIPMENT

    HCPCS Level II E0111: Crutch, Forearm, With Tip and Handgrips

    HCPCS-E0112-UNDERARM-WOOD-CRUTCHES-PAIR

    HCPCS Level II E0112: Underarm Wooden Crutches, Pair

    HCPCS-E0113-CRUTCH-UNDERARM-WOOD-ADJUSTABLE-FIXED-WITH-PAD-TIP-HANDGRIP

    HCPCS Level II E0113: Crutch Underarm, Wood, Adjustable or Fixed

    HCPCS-E0114-UNDERARM-CRUTCHES-PAIR-ADJUSTABLE-FIXED

    HCPCS Level II E0114: Underarm (Axillary) Crutches, Adjustable or Fixed, Pair

    HCPCS-E0116-UNDERARM-CRUTCH-NON-WOOD-ADJUSTABLE-FIXED

    HCPCS E0116: Underarm Crutch, Non-Wood, Adjustable/Fixed with Pad

    HCPCS-E0117-ARTICULATING-SPRING-ASSISTED-UNDERARM-CRUTCH

    HCPCS Level II E0117: Crutch, Underarm, Articulating, Spring-Assisted

    HCPCS-E0118-LOWER-LEG-PLATFORM-CRUTCH-SUBSTITUTE

    HCPCS E0118: Crutch Substitute, Lower Leg Platform

    Showing 1–10 of 670

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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