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    OpenPayerNPI Medicare & MedicaidExagen Inc.
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    Exagen Inc. — Billing Profile & Reimbursement Data

    NPI 1245494517 · Vista, CA · Clinical Medical Laboratory

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    Exagen Inc. is a clinical medical laboratory provider located in Vista, California. This profile covers 23 Medicare and 31 Medicaid CPT/HCPCS procedure codes, with claims volume, average reimbursement, and total revenue by code, benchmarked against other providers billing the same services.

    Provider details (source: NPPES NPI Registry)

    FieldValue
    Entity TypeOrganization
    OrganizationExagen Inc.
    Address1261 Liberty Way Ste C
    CityVista
    StateCA
    ZIP92081
    TaxonomyClinical Medical Laboratory
    NPI EnumeratedJuly 15, 2008

    Lifetime revenue by payer source (source: CMS Medicare & Medicaid claims data)

    Payer SourceTotal Paid
    Medicare$15.7M
    Medicaid$4.7M

    Key Findings

    EXAGEN INC. operates as a clinical medical laboratory with a clear focus on autoimmune and immunology testing; its proprietary PLA test 0312U (Avise® Lupus) alone generated $11.2M in Medicare revenue and represents 71.2% of the provider’s total Medicare revenue, indicating the lab’s core service line centers on a branded lupus diagnostic. The PLA nature of 0312U (reported only for Avise® Lupus from Exagen, Inc.) explains why this single code dominates Medicare receipts and why national peer volume comparison is not available for that code.

    Medicare revenue is highly concentrated: the precomputed top three Medicare codes account for 83.9% of the provider’s total Medicare revenue. Those top contributors include 0312U ($11.2M, 71.2%), 86235 ($1.1M, 7.1%), and 86147 ($869.9K, 5.5%), which together drive the vast majority of the Medicare business and suggest reliance on a narrow set of high-volume autoimmune assays.

    On Medicare, EXAGEN shows extreme national concentration for multiple tests and mixed comparability: 0312U ranks #1 of 1 providers nationally (no peer-volume comparison available), 86235 ranks #5 of 746 providers nationally (99th percentile, labeled an "extreme outlier"), and both 86147 and 86146 rank #1 of their peer sets (100th percentile, labeled "extreme outlier"). These rank and percentile signals indicate EXAGEN is a dominant reporter of several specific immunology/autoantibody assays at the national level or is uniquely positioned for proprietary testing.

    Medicaid billing is more distributed but still shows concentrated lines: the precomputed top three Medicaid codes account for 45.6% of the provider’s total Medicaid revenue, with 86235 contributing $1M (22.2%), 86146 $556.2K (11.9%), and 0312U $538K (11.5%). This mix indicates the same autoimmune-focused assays drive a substantial share of the Medicaid business, though with a lower single-test concentration than Medicare.

    Within California Medicaid, EXAGEN is a leading in-state performer on multiple codes: 86146, 86147, 88184, and 88187 all rank #1 among in-state peers (100th percentile, often called an "extreme outlier"), while 86235 ranks #3 of 125 providers in-state (98th percentile, also labeled an "extreme outlier"). These statewide rank patterns identify EXAGEN as a major provider for antiphospholipid, ENA, and flow cytometry–related services in California’s Medicaid network.

    The provider’s public-payer mix favors Medicare by scale: lifetime Medicare revenue is $15.7M versus total Medicaid revenue of $4.7M, so Medicare represents the larger share of reported public-payer income on file. Analysts should treat EXAGEN as Medicare-weighted when modeling public-payer exposure or negotiating Medicare-focused contracts.

    EXAGEN’s NPI was enumerated on 2008-07-15 (~18 years ago), indicating a long-standing presence in billing data; combined with the high concentration in a proprietary PLA (0312U) and numerous 100th-percentile ranks, this tenure supports interpretation of the pattern as an established business model focused on specialized autoimmune diagnostics rather than a new entrant.

    Multiple codes across both payers are explicitly labeled in the dataset as "extreme outlier" or "notably above typical" (for example, 86235, 86147, 86146, 88184), which makes EXAGEN highly visible for utilization and contracting review. Given the concentration in a few specialized assays (notably 0312U) and the strong in-state dominance on several Medicaid codes, payers and network managers should consider targeted utilization benchmarking, contract terms, or clinical validation pathways specific to autoimmune and flow-cytometry services when engaging with this lab.

    Medicare: Total Revenue Breakdown by CPT/HCPCS Code

    Medicare revenue breakdown by CPT/HCPCS procedure code.

    View: Bar Chart1 / 2

    Medicare: Complete Services Breakdown

    The CPT/HCPCS codes generating the most Medicare revenue for this provider.

    23 rows

    CPT/HCPCS CodeDescriptionClaimsAvg PaidRevenue
    0312UThis is a Proprietary Laboratory Analyses (PLA) code, meaning that the code applies to only one unique lab test made by a specific manufacturer or performed by a specific lab. Report 0312U to be…13,590$820$11.2M
    86235The lab analyst performs an assay to evaluate the patient’s serum for each antibody to an extractable nuclear antigen, also called ENA. Types of ENA antibodies include anti ribonuclear protein,…62,280$20$1.1M
    86147The lab analyst performs the technical lab test to analyze for the presence of antibodies to cardiolipin, also called antiphospholipids. Report this code once for each immunoglobulin class the…34,800$30$869.9K
    86146The lab analyst performs the technical lab test to analyze the sample, such as serum, for the presence of beta 2 glycoprotein I antibody. Report one unit for each antibody.34,660$30$866.6K
    83516The lab analyst performs the technical immunoassay test involving several steps to detect and measure an analyte of a noninfectious nature. The results show as positive or negative, or in…25,720$10$282.9K
    86800A lab analyst performs an immunoassay to evaluate the patient’s serum for antibodies to thyroglobulin, a protein produced by the thyroid gland that synthesizes, stores, and releases thyroid hormones.14,900$20$238.4K
    86376The lab analyst performs a technical test to analyze a sample, typically serum, for microsomal antibodies, such as liver, kidney microsomal, called LKM1, or thyroid peroxidase, called TPO, which are…14,820$10$207.5K
    86431The lab analyst performs a test to evaluate the level of rheumatoid factor, or RF, in patient blood.29,530$10$177.2K
    86148The lab analyst performs the technical lab steps for an antiphosphatidylserine antibody test, also called APA, to detect antibodies against proteins typically found on cell membranes and platelets.…9,550$20$152.9K
    83876The lab analyst measures the amount of myeloperoxidase, an enzyme present in neutrophils, in the patient specimen.2,750$50$137.5K

    Showing 1–10 of 23

    Medicare: Competitive Analysis & Benchmarks

    How this provider's Medicare billing volume and revenue compare to other providers nationally and within its state, across 23 CPT/HCPCS codes.

    View: State1 / 2

    Full comparison — all codes billed, vs. state median

    23 rows

    CPT/HCPCS CodeRankProvider CountMedian ClaimsAvg PaidAverage Revenue
    0312U11013,590$820$11.2M
    8818531401,560$20$139.2K
    862352601,220$20$75.7K
    86146130240$20$45.3K
    86147140200$20$44.7K
    86148110990$20$37.6K
    8387611070$50$34.8K
    83520340230$20$23.5K
    8818434070$70$21.4K
    82397110420$10$19.5K

    Showing 1–10 of 23

    Medicaid: Total Revenue Breakdown by CPT/HCPCS Code

    Medicaid revenue breakdown by year and by CPT/HCPCS procedure code, including monthly billing trends and the top codes driving revenue.

    View: By Year1 / 3

    Medicaid: Complete Services Breakdown

    Every CPT/HCPCS code this provider has billed to Medicaid, with claims volume, average payment, and total revenue.

    31 rows

    CPT/HCPCS CodeDescriptionClaimsAvg PaidRevenue
    86235The lab analyst performs an assay to evaluate the patient’s serum for each antibody to an extractable nuclear antigen, also called ENA. Types of ENA antibodies include anti ribonuclear protein,…79,780$10$1M
    86146The lab analyst performs the technical lab test to analyze the sample, such as serum, for the presence of beta 2 glycoprotein I antibody. Report one unit for each antibody.79,450$10$556.2K
    0312UThis is a Proprietary Laboratory Analyses (PLA) code, meaning that the code applies to only one unique lab test made by a specific manufacturer or performed by a specific lab. Report 0312U to be…15,370$40$538K
    86147The lab analyst performs the technical lab test to analyze for the presence of antibodies to cardiolipin, also called antiphospholipids. Report this code once for each immunoglobulin class the…79,480$10$476.9K
    88184The lab analyst performs the technical component of a flow cytometry procedure using a cell surface, cytoplasmic, or nuclear marker to characterize cells and aid clinicians in diagnosing patients…25,060$10$275.6K
    88187The clinician, typically a pathologist, interprets flow cytometry results of two to eight markers.22,000$10$264K
    83516The lab analyst performs the technical immunoassay test involving several steps to detect and measure an analyte of a noninfectious nature. The results show as positive or negative, or in…52,050$1$208.2K
    86800A lab analyst performs an immunoassay to evaluate the patient’s serum for antibodies to thyroglobulin, a protein produced by the thyroid gland that synthesizes, stores, and releases thyroid hormones.41,020$1$164.1K
    86431The lab analyst performs a test to evaluate the level of rheumatoid factor, or RF, in patient blood.78,760$1$157.5K
    83520The lab analyst measures the analyte, which is not an infectious agent antibody or infectious agent antigen, by immunoassay. Use 83520 for procedures that have no specific code assigned for the…29,790$10$149K

    Showing 1–10 of 31

    Medicaid: Competitive Analysis & Benchmarks

    How this provider's Medicaid billing volume and revenue compare to other California providers billing the same CPT/HCPCS codes.

    Full comparison — all codes billed, vs. California median

    31 rows

    CPT/HCPCS CodeDescriptionRankProvider CountMedian ClaimsAvg PaidAverage Revenue
    0312UThis is a Proprietary Laboratory Analyses (PLA) code, meaning that the code applies to only one unique lab test made by a specific manufacturer or performed by a specific lab. Report 0312U to be…11015,370$30$533.2K
    88185The lab analyst performs the technical component of a flow cytometry procedure using cell surface, cytoplasmic, or nuclear markers to characterize cells and aid clinicians in diagnosing patients with…140220$140$354.7K
    82542The lab analyst performs the technical lab test to evaluate the specimen for the presence or amount of a nondrug analyte by using column chromatography and possibly mass spectrometry.1030170$30$197.6K
    86235The lab analyst performs an assay to evaluate the patient’s serum for each antibody to an extractable nuclear antigen, also called ENA. Types of ENA antibodies include anti ribonuclear protein,…3130280$20$85.9K
    85025A complete blood count (better known as a CBC) is a blood test request by a doctor that provides detailed information about various types of cells in a patient's blood. Usually a pathologist or a…1,9112,1001,130$1$83.5K
    88184The lab analyst performs the technical component of a flow cytometry procedure using a cell surface, cytoplasmic, or nuclear marker to characterize cells and aid clinicians in diagnosing patients…140240$30$62.7K
    80299Use 80299 to report therapeutic drug quantitation procedures that do not have a specific code.2560210$20$60K
    86146The lab analyst performs the technical lab test to analyze the sample, such as serum, for the presence of beta 2 glycoprotein I antibody. Report one unit for each antibody.140130$10$41.5K
    86147The lab analyst performs the technical lab test to analyze for the presence of antibodies to cardiolipin, also called antiphospholipids. Report this code once for each immunoglobulin class the…150130$10$41.1K
    83520The lab analyst measures the analyte, which is not an infectious agent antibody or infectious agent antigen, by immunoassay. Use 83520 for procedures that have no specific code assigned for the…6130270$10$26.9K

    Showing 1–10 of 31

    Nearby Providers

    Other providers in the same ZIP code as Exagen Inc., ranked by combined Medicare and Medicaid revenue.

    ProviderStateTaxonomyMedicare RevenueMedicaid Revenue
    Patrick LinsonCARadiation Oncology Physician$1.4M$0
    Norbert KasedCARadiation Oncology Physician$1.2M$0
    Hanh BuiCACardiovascular Disease Physician$795.6K$5.4K
    Aftab QaziCAFamily Medicine Physician$88.7K$540.6K
    Eva LeanCARadiation Oncology Physician$508.8K$0
    Jeanny RickardsCAFoot & Ankle Surgery Podiatrist$454.2K$0
    Lindsey WilkeCAFoot & Ankle Surgery Podiatrist$393.6K$0
    Marc GarberCAPhysical Therapist$292.7K$0
    Derek HeltonCAHematology & Oncology Physician$206.8K$0
    Michael HollsteggeCAPhysical Therapist$177.3K$0

    Frequently Asked Questions

    References

    1. 1.Medicare Physician & Other Practitioner by Provider and Service. CMS.gov.Provider-level Medicare Part B utilization and payment data.
    2. 2.NPPES NPI Registry. CMS.gov.National Provider Identifier registry used for provider enumeration and taxonomy metadata.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

    Medicare Revenue by CPT/HCPCS Code
    Claims Volume vs. California Distribution
    Exagen Inc. — 14 of 23 codes billed far more than typical (above p95)
    p5–p95 (all providers)p25–p75MedianThis providerOutlier
    Rank Distribution — California
    Medicaid Revenue by Year vs. California Providers
    0 of 7 years billed far more than typical (above p95)
    p5–p95 (all providers)p25–p75MedianThis providerOutlier
    Claims Volume vs. California Distribution
    Exagen Inc. — 20 of 25 codes billed far more than typical (above p95)
    p5–p95 (all providers)p25–p75MedianThis providerOutlier
    Rank Distribution — California