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    OpenPayerNPI Medicare & MedicaidAssurex Health, Inc.
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    Assurex Health, Inc. — Billing Profile & Reimbursement Data

    NPI 1235363052 · Mason, OH · Clinical Medical Laboratory

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    Assurex Health, Inc. is a clinical medical laboratory provider located in Mason, Ohio. This profile covers 4 Medicare and 11 Medicaid CPT/HCPCS procedure codes, with claims volume, average reimbursement, and total revenue by code, benchmarked against other providers billing the same services.

    Provider details (source: NPPES NPI Registry)

    FieldValue
    Entity TypeOrganization
    OrganizationAssurex Health, Inc.
    Address6000 S Mason Montgomery Rd
    CityMason
    StateOH
    ZIP45040
    TaxonomyClinical Medical Laboratory
    NPI EnumeratedMay 7, 2009

    Lifetime revenue by payer source (source: CMS Medicare & Medicaid claims data)

    Payer SourceTotal Paid
    Medicaid$90.3M
    Medicare$27.3M

    Key Findings

    This lab’s payer mix is skewed toward Medicaid by scale: total Medicare revenue is $27.3M while total Medicaid revenue is $90.3M, indicating Medicaid drives a substantially larger portion of the provider’s business. Both payers show concentrated molecular/genetic testing lines rather than broad clinical lab panels.

    Medicare revenue is highly concentrated: the precomputed top-3 Medicare codes account for 100.0% of Medicare revenue, driven primarily by 0345U (87.7% of Medicare revenue), with 81226 (9.4%) and 81225 (2.8%) completing the trio. That mix signals a business model centered on proprietary pharmacogenomic testing (0345U GeneSight psychotropic) plus targeted CYP450 genotyping for medication metabolism.

    Competitive standing on Medicare for gene-specific tests is extreme relative to peers: 81226 and 81225 each rank #1 nationally (100th percentile) and are labeled extreme outlier volumes, while 0345U ranks #1 of 1 providers nationally (0th percentile; no national peer volume comparison available). These rankings indicate the provider is a dominant national source for certain CYP2D6/CYP2C19 testing volumes and is effectively the listed source for the proprietary 0345U test.

    On Medicaid the top three codes are responsible for 55.2% of Medicaid revenue, with 0345U contributing 20.7%, 81479 contributing 19.4%, and 81381 contributing 15.1%. This concentration shows that Medicaid revenue is split between the same proprietary pharmacogenomic product and higher-volume uncoded or broad molecular pathology and HLA testing lines.

    The provider is a dominant in-state player for numerous molecular genetics and pharmacogenetic codes: multiple top Medicaid codes (81479, 81381, 81226, 81225, 81227, 81230, 81291) rank #1 in-state and are annotated as 100th percentile or notably above typical state volume. Several Medicaid codes (including 0345U and 81418) also appear as the only in-state reporting provider (0th percentile; no state peer volume comparison available), reinforcing a strong local market position for these services.

    Operational capabilities implied by the code mix include proprietary psychotropic pharmacogenomic testing (0345U GeneSight) plus a broad suite of CYP and multigene pharmacogenetic analyses (81226, 81225, 81227, 81230, 81418) and HLA testing (81381). The presence of high-volume unspecified molecular pathology reporting under 81479 and algorithmic test codes like 81599 suggests both custom/miscellaneous molecular work and multianalyte assays in the service portfolio.

    Reimbursement patterns vary sharply by payer and code: Medicare average paid per claim for 0345U is $1324 while Medicaid average paid per claim for the same code is $147, and other codes show similar payer-level payment differentials. These differences imply the provider’s revenue per-test economics are materially influenced by payer mix and by which payer is being billed for high-value proprietary tests.

    The provider has an established operational tenure, with NPI enumeration dated 2009-05-07 (~17 years ago), consistent with the organization operating at scale and having time to build the high volumes and market positioning observed across both Medicare and Medicaid claims.

    Medicare: Total Revenue Breakdown by CPT/HCPCS Code

    Medicare revenue breakdown by CPT/HCPCS procedure code.

    View: Bar Chart1 / 2

    Medicare: Complete Services Breakdown

    The CPT/HCPCS codes generating the most Medicare revenue for this provider.

    4 rows

    CPT/HCPCS CodeDescriptionClaimsAvg PaidRevenue
    0345UThis is a Proprietary Laboratory Analyses (PLA) code, meaning that the code applies to only one unique lab test made by a specific manufacturer or performed by a specific lab. Report 0345U only for…18,120$1,320$24M
    81226The lab analyst performs the technical lab test to detect the presence of common changes in the gene for cytochrome P450, family 2, subfamily D, polypeptide 6, also known as CYP2D6.5,830$440$2.6M
    81225The lab analyst performs the technical lab test to detect the presence of common changes in the gene for cytochrome P450, family 2, subfamily C, polypeptide 19, also known as CYP2C19.2,710$290$772.6K
    81381The lab analyst performs the technical lab test for high resolution assessment of human leukocyte antigen genes, called HLA, for one Class I allele or allele group of interest, typically one that is…70$170$11K

    Medicare: Competitive Analysis & Benchmarks

    How this provider's Medicare billing volume and revenue compare to other providers nationally and within its state, across 4 CPT/HCPCS codes.

    View: State1 / 2

    Full comparison — all codes billed, vs. state median

    4 rows

    CPT/HCPCS CodeRankProvider CountMedian ClaimsAvg PaidAverage Revenue
    0345U11018,120$1,320$24M
    8122611030$440$862.5K
    812251101,370$290$391.2K
    8138111040$160$6.8K

    Medicaid: Total Revenue Breakdown by CPT/HCPCS Code

    Medicaid revenue breakdown by year and by CPT/HCPCS procedure code, including monthly billing trends and the top codes driving revenue.

    View: By Year1 / 3

    Medicaid: Complete Services Breakdown

    Every CPT/HCPCS code this provider has billed to Medicaid, with claims volume, average payment, and total revenue.

    11 rows

    CPT/HCPCS CodeDescriptionClaimsAvg PaidRevenue
    0345UThis is a Proprietary Laboratory Analyses (PLA) code, meaning that the code applies to only one unique lab test made by a specific manufacturer or performed by a specific lab. Report 0345U only for…126,630$150$18.6M
    81479Use 81479 to report a molecular pathology procedure that does not have a specific code.378,280$50$17.4M
    81381The lab analyst performs the technical lab test for high resolution assessment of human leukocyte antigen genes, called HLA, for one Class I allele or allele group of interest, typically one that is…386,360$40$13.5M
    81226The lab analyst performs the technical lab test to detect the presence of common changes in the gene for cytochrome P450, family 2, subfamily D, polypeptide 6, also known as CYP2D6.345,420$40$13.5M
    81225The lab analyst performs the technical lab test to detect the presence of common changes in the gene for cytochrome P450, family 2, subfamily C, polypeptide 19, also known as CYP2C19.347,020$30$10.1M
    81418Code 81418 describes a test to evaluate a blood or saliva specimen for changes in at least six genes that may impact metabolism of many therapeutic drugs. The test must include CYP2C19 and CYP2D6…35,970$150$5.5M
    81227The lab analyst performs the technical lab test to detect the presence of common changes in the gene for cytochrome P450, family 2, subfamily C, polypeptide 9, also known as CYP2C9.344,670$10$4.5M
    81230The lab analyst performs the technical lab test to analyze the common variants of the cytochrome P450 family 3 subfamily A member 4 gene (CYP3A4), such as *2, *22.334,390$10$4M
    81291The lab analyst performs the technical lab test to detect the presence of common changes in the gene for 5,10–methylenetetrahydrofolate reductase, also known as MTHFR.325,520$10$1.6M
    81599Use 81599 to report a multianalyte assay with algorithmic analysis, or MAAA test, that does not have a specific Category I code or an administrative code in Appendix O.109,790$10$768.5K

    Showing 1–10 of 11

    Medicaid: Competitive Analysis & Benchmarks

    How this provider's Medicaid billing volume and revenue compare to other Ohio providers billing the same CPT/HCPCS codes.

    Full comparison — all codes billed, vs. Ohio median

    11 rows

    CPT/HCPCS CodeDescriptionRankProvider CountMedian ClaimsAvg PaidAverage Revenue
    0345UThis is a Proprietary Laboratory Analyses (PLA) code, meaning that the code applies to only one unique lab test made by a specific manufacturer or performed by a specific lab. Report 0345U only for…110126,630$150$18.6M
    81418Code 81418 describes a test to evaluate a blood or saliva specimen for changes in at least six genes that may impact metabolism of many therapeutic drugs. The test must include CYP2C19 and CYP2D6…11035,970$150$5.5M
    81381The lab analyst performs the technical lab test for high resolution assessment of human leukocyte antigen genes, called HLA, for one Class I allele or allele group of interest, typically one that is…1101,140$40$3.4M
    81226The lab analyst performs the technical lab test to detect the presence of common changes in the gene for cytochrome P450, family 2, subfamily D, polypeptide 6, also known as CYP2D6.11080$40$2.7M
    81225The lab analyst performs the technical lab test to detect the presence of common changes in the gene for cytochrome P450, family 2, subfamily C, polypeptide 19, also known as CYP2C19.11090$30$2M
    81479Use 81479 to report a molecular pathology procedure that does not have a specific code.110760$50$2M
    81227The lab analyst performs the technical lab test to detect the presence of common changes in the gene for cytochrome P450, family 2, subfamily C, polypeptide 9, also known as CYP2C9.110260$10$1.5M
    81230The lab analyst performs the technical lab test to analyze the common variants of the cytochrome P450 family 3 subfamily A member 4 gene (CYP3A4), such as *2, *22.110260$10$1.4M
    81599Use 81599 to report a multianalyte assay with algorithmic analysis, or MAAA test, that does not have a specific Category I code or an administrative code in Appendix O.110109,790$10$750K
    81291The lab analyst performs the technical lab test to detect the presence of common changes in the gene for 5,10–methylenetetrahydrofolate reductase, also known as MTHFR.110140$10$282.4K

    Showing 1–10 of 11

    Related Providers

    Other providers that share a Tax Identification Number (TIN) with Assurex Health, Inc., ranked by combined Medicare and Medicaid revenue.

    ProviderStateTaxonomyMedicare RevenueMedicaid Revenue
    Laboratory Corporation Of America HoldingsNCClinical Medical Laboratory$214.6M$1.4B
    Laboratory Corporation Of America HoldingsNJClinical Medical Laboratory$143.3M$717.5M
    Natera, Inc.CAClinical Medical Laboratory$133.1M$641.5M
    Unilab CorporationCAClinical Medical Laboratory$94M$668.5M
    Quest Diagnostics IncorporatedNJClinical Medical Laboratory$111.2M$637.7M
    Bioreference Health, LLCNJClinical Medical Laboratory$66.8M$620.1M
    Laboratory Corporation Of America HoldingsOHClinical Medical Laboratory$56.9M$617M
    Millennium Health, LLCCAClinical Medical Laboratory$20.4M$579.3M
    Exact Sciences Laboratories, LLCWIClinical Medical Laboratory$299.3M$276.5M
    Aeroflow Inc.NCDurable Medical Equipment & Medical Supplies$0$571.9M

    Nearby Providers

    Other providers in the same ZIP code as Assurex Health, Inc., ranked by combined Medicare and Medicaid revenue.

    ProviderStateTaxonomyMedicare RevenueMedicaid Revenue
    Queen City Hospice, LLCOHCommunity Based Hospice Care Agency$0$61.1M
    Mira Precision Health, IncOHClinical Medical Laboratory$313.2K$15M
    Amazing Smiles Dental, LLCOHGeneral Practice Dentistry$0$12.1M
    Luxottica Of America Inc.OHPoint of Service$0$7.7M
    Elizabeth UhlenhakeOHDermatology Physician$966.3K$0
    Samir PatelOHDermatology Physician$936.5K$0
    Southwest Ohio Pain Management LLCOHAmbulatory Surgical Clinic/Center$661.3K$0
    City Of Mason OhioOHAmbulance$308.9K$292.7K
    Edward MeierOHOphthalmology Physician$339.3K$0
    Nathan WeirOHDermatology Physician$245.3K$0

    Frequently Asked Questions

    References

    1. 1.Medicare Physician & Other Practitioner by Provider and Service. CMS.gov.Provider-level Medicare Part B utilization and payment data.
    2. 2.NPPES NPI Registry. CMS.gov.National Provider Identifier registry used for provider enumeration and taxonomy metadata.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

    Medicare Revenue by CPT/HCPCS Code
    Claims Volume vs. Ohio Distribution
    Assurex Health, Inc. — 3 of 4 codes billed far more than typical (above p95)
    p5–p95 (all providers)p25–p75MedianThis providerOutlier
    Rank Distribution — Ohio
    Medicaid Revenue by Year vs. Ohio Providers
    7 of 7 years billed far more than typical (above p95)
    p5–p95 (all providers)p25–p75MedianThis providerOutlier
    Claims Volume vs. Ohio Distribution
    Assurex Health, Inc. — 8 of 11 codes billed far more than typical (above p95)
    p5–p95 (all providers)p25–p75MedianThis providerOutlier
    Rank Distribution — Ohio