ICD-10-PCS Code For Brain: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group X053 includes procedures performed to destroy tissue in the brain. These ICD-10-PCS codes are used for inpatient documentation when focused ultrasound therapy is applied externally to ablate part or all of the brain tissue for therapeutic purposes. Accurate coding within the ICD-10-PCS X053 group is essential for proper inpatient reimbursement, as it captures the specific destructive procedure performed and supports clinical documentation accuracy.

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Brain Destruction Procedure Overview

Procedures in this group involve the targeted destruction of all or part of the brain using energy-based methods, specifically focused ultrasound therapy applied externally. These procedures target the nervous system and are used to ablate neural tissue for therapeutic reasons. Accurate coding ensures inpatient records reflect the specific destructive operation and body part treated, which affects documentation and reimbursement.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
0	Body System	Nervous System
5	Operation	Destruction
3	Body Part	Brain

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ICD-10-PCS Code For Brain: Procedure Code Group Overview

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Brain Destruction Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
0	Body System	Nervous System
5	Operation	Destruction
3	Body Part	Brain

When to Use

Use a code from this group when focused ultrasound therapy is performed externally to intentionally ablate or destroy brain tissue as the operative action. These codes apply when the documented operation is destruction of the brain and the procedure is performed in an inpatient setting.

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
X053X4B	Destruction of Brain using Focused Ultrasound Therapy, External Approach, New Technology Group 11

DRG Codes

16 rows

DRG Code	Description
025	Craniotomy and Endovascular Intracranial Procedures with MCC
026	Craniotomy and Endovascular Intracranial Procedures with CC
027	Craniotomy and Endovascular Intracranial Procedures without CC/MCC
820	Lymphoma and Leukemia with Major O.R. Procedures with MCC
821	Lymphoma and Leukemia with Major O.R. Procedures with CC
822	Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC
826	Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures with MCC
827	Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures with CC
828	Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures without CC/MCC
907	Other O.R. Procedures for Injuries with MCC

Showing 1–10 of 16

Typical Clinical Scenarios

An elderly patient with medication-refractory essential tremor presents electively after multidisciplinary evaluation for symptomatic management; imaging confirms a well-defined thalamic target and the team admits the patient for a planned focused ultrasound ablation to reduce tremor severity when medication and other therapies have failed. The procedure uses externally delivered focused ultrasound energy to destroy the targeted brain tissue and is performed in the inpatient setting for monitoring and procedural logistics. Typical codes: X053X4B
A middle-aged patient with levodopa-resistant, disabling Parkinsonian tremor is admitted for a scheduled neurosurgical procedure after preoperative functional mapping demonstrates a unilateral deep brain target amenable to noninvasive ablation; the goal is to palliate motor symptoms by destroying a small area of brain tissue with focused ultrasound delivered externally. Inpatient admission is for the therapeutic destruction procedure and postprocedural observation for neurologic changes. Typical codes: X053X4B
A patient with recurrent focal epileptogenic lesion not controlled by medications and who previously underwent other treatments is admitted urgently for multidisciplinary reassessment and undergoes externally applied focused ultrasound destruction of the epileptogenic brain focus when minimally invasive open surgery is contraindicated; inpatient care is required for perioperative monitoring of seizures and neurologic status. Typical codes: X053X4B

ICD-10-PCS Code For Renal Sympathetic Nerve(s): Procedure Code Group Overview

X052-THORACIC-SYMPATHETIC-NERVE-DESTRUCTION

ICD-10-PCS Code For Thoracic Sympathetic Nerve, Cardiac Plexus: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
X053X4B	Destruction of Brain using Focused Ultrasound Therapy, External Approach, New Technology Group 11

DRG Codes

16 rows

DRG Code	Description
025	Craniotomy and Endovascular Intracranial Procedures with MCC
026	Craniotomy and Endovascular Intracranial Procedures with CC
027	Craniotomy and Endovascular Intracranial Procedures without CC/MCC
820	Lymphoma and Leukemia with Major O.R. Procedures with MCC
821	Lymphoma and Leukemia with Major O.R. Procedures with CC
822	Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC
826	Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures with MCC
827	Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures with CC
828	Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures without CC/MCC
907	Other O.R. Procedures for Injuries with MCC

Showing 1–10 of 16

Typical Clinical Scenarios

An elderly patient with medication-refractory essential tremor presents electively after multidisciplinary evaluation for symptomatic management; imaging confirms a well-defined thalamic target and the team admits the patient for a planned focused ultrasound ablation to reduce tremor severity when medication and other therapies have failed. The procedure uses externally delivered focused ultrasound energy to destroy the targeted brain tissue and is performed in the inpatient setting for monitoring and procedural logistics. Typical codes: X053X4B
A middle-aged patient with levodopa-resistant, disabling Parkinsonian tremor is admitted for a scheduled neurosurgical procedure after preoperative functional mapping demonstrates a unilateral deep brain target amenable to noninvasive ablation; the goal is to palliate motor symptoms by destroying a small area of brain tissue with focused ultrasound delivered externally. Inpatient admission is for the therapeutic destruction procedure and postprocedural observation for neurologic changes. Typical codes: X053X4B
A patient with recurrent focal epileptogenic lesion not controlled by medications and who previously underwent other treatments is admitted urgently for multidisciplinary reassessment and undergoes externally applied focused ultrasound destruction of the epileptogenic brain focus when minimally invasive open surgery is contraindicated; inpatient care is required for perioperative monitoring of seizures and neurologic status. Typical codes: X053X4B

ICD-10-PCS Code For Renal Sympathetic Nerve(s): Procedure Code Group Overview

X052-THORACIC-SYMPATHETIC-NERVE-DESTRUCTION

ICD-10-PCS Code For Thoracic Sympathetic Nerve, Cardiac Plexus: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

OpenPayer

ICD-10-PCS Code For Brain: Procedure Code Group Overview

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Brain Destruction Procedure Overview

Code Attributes

OpenPayer

ICD-10-PCS Code For Brain: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Brain: Procedure Code Group Overview policy alerts

Brain Destruction Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

References

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

References

ICD-10-PCS Code For Brain: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Brain: Procedure Code Group Overview policy alerts

Brain Destruction Procedure Overview

Code Attributes

ICD-10-PCS Code For Brain: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Brain: Procedure Code Group Overview policy alerts

Brain Destruction Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS code represents destruction of the brain using focused ultrasound therapy externally?

What clinical action does ICD-10-PCS code group X053 capture?

For what inpatient documentation and administrative purposes is accurate coding within X053 important?

What are the ICD-10-PCS code attributes for the brain destruction procedure group X053?

Which DRG categories may relate to procedures coded in X053?

References

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS code represents destruction of the brain using focused ultrasound therapy externally?

What clinical action does ICD-10-PCS code group X053 capture?

For what inpatient documentation and administrative purposes is accurate coding within X053 important?

What are the ICD-10-PCS code attributes for the brain destruction procedure group X053?

Which DRG categories may relate to procedures coded in X053?

References