ICD-10-CM Code For Other Infections Specific To The Perinatal Period: Group Overview

The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group P39 includes infections of the newborn that are specific to the perinatal period and do not fall under more specific perinatal infection codes, covering a range of bacterial, viral, or other infectious etiologies affecting neonates. These ICD-10-CM diagnosis codes are used to document clinical scenarios such as neonatal systemic or localized infections acquired in utero, during delivery, or shortly after birth, capturing disease severity, organ involvement, or clinical complexity relevant to this group. Accurate coding within the ICD-10-CM P39 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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ICD-10-CM P39: Other Infections Specific To The Perinatal Period Overview

This group includes infections that affect newborns during the perinatal period and are not captured in other specific perinatal infection categories. These conditions target neonatal systems and can include systemic or localized infectious processes acquired in utero, during delivery, or shortly after birth. Accurate coding is important for complete clinical documentation and can affect reimbursement and public health tracking.

When to Use

Use a code from this group when a newborn has an infection attributed to the perinatal period that does not meet criteria for more specific perinatal infection codes. These codes apply when documentation indicates timing around birth and infectious etiology without a more specific coded diagnosis.

ICD-10-CM Codes

7 rows

ICD-10-CM Code	Description
P39.0	Neonatal infective mastitis
P39.1	Neonatal conjunctivitis and dacryocystitis
P39.2	Intra-amniotic infection affecting newborn, not elsewhere classified
P39.3	Neonatal urinary tract infection
P39.4	Neonatal skin infection
P39.8	Other specified infections specific to the perinatal period
P39.9	Infection specific to the perinatal period, unspecified

DRG Codes

3 rows

DRG Code	Description
791	Prematurity with Major Problems
793	Full Term Neonate with Major Problems
794	Neonate with Other Significant Problems

Typical Clinical Scenarios

A term neonate develops worsening respiratory distress and systemic signs (fever, lethargy) within 24–72 hours of birth after prolonged rupture of membranes and maternal intrapartum infection; workup shows positive blood cultures for group B Streptococcus and signs of sepsis, prompting NICU admission and antimicrobial therapy. A code from this group is assigned because the newborn has a perinatal bacterial infection causing systemic illness. Typical codes: P39.0
A newborn in the first week of life presents with petechial rash, thrombocytopenia, and elevated liver enzymes after documented congenital TORCH exposure; evaluation demonstrates evidence of transplacental viral infection acquired before or during delivery, requiring monitoring for organ dysfunction and supportive care. A diagnosis from this group is used to identify the specific perinatal viral infection affecting the neonate. Typical codes: P39.1, P39.2
A neonate with a prolonged NICU course develops late-onset localized infection of the skin and soft tissue at a vascular catheter insertion site, with negative systemic cultures but clinical signs of localized infection and cellulitis complicating the perinatal period; this is coded to reflect an infection specific to the perinatal timeframe that complicates care and may affect length of stay. Typical codes: P39.8, P39.9}

Related Codes

P35-CONGENITAL-VIRAL-DISEASES

ICD-10-CM Code For Congenital Viral Diseases: Group Overview

P36-BACTERIAL-SEPSIS-OF-NEWBORN

ICD-10-CM Code For Bacterial Sepsis Of Newborn: Group Overview

P37-OTHER-CONGENITAL-INFECTIONS

ICD-10-CM Code For Other Congenital Infectious And Parasitic Diseases: Group Overview

P38-OMPHALITIS-OF-NEWBORN

ICD-10-CM Code For Omphalitis Of Newborn: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-CM Codes

7 rows

ICD-10-CM Code	Description
P39.0	Neonatal infective mastitis
P39.1	Neonatal conjunctivitis and dacryocystitis
P39.2	Intra-amniotic infection affecting newborn, not elsewhere classified
P39.3	Neonatal urinary tract infection
P39.4	Neonatal skin infection
P39.8	Other specified infections specific to the perinatal period
P39.9	Infection specific to the perinatal period, unspecified

DRG Codes

3 rows

DRG Code	Description
791	Prematurity with Major Problems
793	Full Term Neonate with Major Problems
794	Neonate with Other Significant Problems

Typical Clinical Scenarios

A term neonate develops worsening respiratory distress and systemic signs (fever, lethargy) within 24–72 hours of birth after prolonged rupture of membranes and maternal intrapartum infection; workup shows positive blood cultures for group B Streptococcus and signs of sepsis, prompting NICU admission and antimicrobial therapy. A code from this group is assigned because the newborn has a perinatal bacterial infection causing systemic illness. Typical codes: P39.0
A newborn in the first week of life presents with petechial rash, thrombocytopenia, and elevated liver enzymes after documented congenital TORCH exposure; evaluation demonstrates evidence of transplacental viral infection acquired before or during delivery, requiring monitoring for organ dysfunction and supportive care. A diagnosis from this group is used to identify the specific perinatal viral infection affecting the neonate. Typical codes: P39.1, P39.2
A neonate with a prolonged NICU course develops late-onset localized infection of the skin and soft tissue at a vascular catheter insertion site, with negative systemic cultures but clinical signs of localized infection and cellulitis complicating the perinatal period; this is coded to reflect an infection specific to the perinatal timeframe that complicates care and may affect length of stay. Typical codes: P39.8, P39.9}

Related Codes

P35-CONGENITAL-VIRAL-DISEASES

ICD-10-CM Code For Congenital Viral Diseases: Group Overview

P36-BACTERIAL-SEPSIS-OF-NEWBORN

ICD-10-CM Code For Bacterial Sepsis Of Newborn: Group Overview

P37-OTHER-CONGENITAL-INFECTIONS

ICD-10-CM Code For Other Congenital Infectious And Parasitic Diseases: Group Overview

P38-OMPHALITIS-OF-NEWBORN

ICD-10-CM Code For Omphalitis Of Newborn: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-CM Code For Other Infections Specific To The Perinatal Period: Group Overview

Sign up for ICD-10-CM Code For Other Infections Specific To The Perinatal Period: Group Overview policy alerts

ICD-10-CM P39: Other Infections Specific To The Perinatal Period Overview

ICD-10-CM Code For Other Infections Specific To The Perinatal Period: Group Overview

Sign up for ICD-10-CM Code For Other Infections Specific To The Perinatal Period: Group Overview policy alerts

ICD-10-CM P39: Other Infections Specific To The Perinatal Period Overview

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-CM codes are included in the P39 group?

What clinical scenarios does ICD-10-CM P39 capture?

How does accurate coding within the `P39` group affect billing and reimbursement?

Which DRGs are related to infections in the perinatal period as noted in the overview?

When should a coder use `P39.8` versus `P39.9`?

References

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-CM codes are included in the P39 group?

What clinical scenarios does ICD-10-CM P39 capture?

How does accurate coding within the `P39` group affect billing and reimbursement?

Which DRGs are related to infections in the perinatal period as noted in the overview?

When should a coder use `P39.8` versus `P39.9`?

References