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    v1.0.28
    OpenPayerBilling CodesInfections specific to the perinatal periodICD-10-CM p35-congenital-viral-diseases
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    ICD-10-CM Code For Congenital Viral Diseases: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group P35 includes congenital viral infections such as cytomegalovirus, herpes simplex, rubella, and other perinatally acquired viral diseases that present at or shortly after birth. These ICD-10-CM diagnosis codes are used to document neonatal infections with attention to timing of onset, organ system involvement, and clinical severity to capture disease burden and treatment needs. Accurate coding within the ICD-10-CM P35 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM P35: Congenital Viral Diseases Overview

    The ICD-10-CM P35 group includes viral infections present at birth that can affect multiple organ systems in the neonate, most commonly the nervous system, sensory organs, and hematologic system. These diagnoses represent perinatal infections acquired in utero or during the birthing process and can lead to long-term morbidity without timely recognition. Accurate coding matters for documenting clinical complexity, justifying necessary neonatal care, and supporting appropriate reimbursement for services related to congenital infection management.

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    When to Use

    Use codes from this group when a viral infection is confirmed or clinically diagnosed in the neonate as being present at birth or identified during the perinatal period. Codes are selected based on the specific viral agent when known, and by documented organ system involvement or complications.

    ICD-10-CM Codes

    7 rows

    ICD-10-CM CodeDescription
    P35.0Congenital rubella syndrome
    P35.1Congenital cytomegalovirus infection
    P35.2Congenital herpesviral [herpes simplex] infection
    P35.3Congenital viral hepatitis
    P35.4Congenital Zika virus disease
    P35.8Other congenital viral diseases
    P35.9Congenital viral disease, unspecified

    DRG Codes

    2 rows

    DRG CodeDescription
    791Prematurity with Major Problems
    793Full Term Neonate with Major Problems

    Typical Clinical Scenarios

    • A term newborn presents within 24 hours of life with microcephaly, petechial rash, hepatosplenomegaly, and thrombocytopenia after known maternal rubella infection during pregnancy; neonatology evaluates for congenital infection and documents the signs attributed to in utero viral transmission, so a congenital viral disease code is assigned to capture the perinatal infection and its manifestations. Typical codes: P35.0, P35.8
    • A premature infant in the NICU develops seizures and chorioretinitis on day 7 of life following maternal cytomegalovirus viremia detected during pregnancy; the infant is worked up for congenital viral infection as the cause of neurologic and ophthalmologic findings, and a specific congenital viral diagnosis code is used to report the perinatal viral etiology. Typical codes: P35.1, P35.8
    • A newborn evaluated for failure to thrive and developmental delay at 3 months of age has a positive laboratory confirmation of congenital herpes simplex virus infection acquired perinatally; the clinic documents the ongoing effects of the congenital viral infection and assigns a congenital viral disease code to reflect the chronic sequelae of the perinatal infection. Typical codes: P35.4, P35.9

    Related Codes

    P36-BACTERIAL-SEPSIS-OF-NEWBORN

    ICD-10-CM Code For Bacterial Sepsis Of Newborn: Group Overview

    P37-OTHER-CONGENITAL-INFECTIONS

    ICD-10-CM Code For Other Congenital Infectious And Parasitic Diseases: Group Overview

    P38-OMPHALITIS-OF-NEWBORN

    ICD-10-CM Code For Omphalitis Of Newborn: Group Overview

    P39-OTHER-INFECTIONS-PERINATAL

    ICD-10-CM Code For Other Infections Specific To The Perinatal Period: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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