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    OpenPayerBilling CodesDiseases of male genital organsICD-10-CM n49-inflammatory-disorders-male-genital
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    ICD-10-CM Code For Inflammatory Disorders Of Male Genital Organs, Not Elsewhere Classified: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group N49 includes inflammatory conditions of male genital organs not classified elsewhere, such as orchitis, epididymitis, and unspecified inflammation of male genital structures. These ICD-10-CM diagnosis codes are used to document clinical encounters involving infection or inflammation of the testis, epididymis, or related male reproductive tissues, capturing severity, laterality, and complications when applicable. Accurate coding within the ICD-10-CM N49 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM N49: Inflammatory Disorders Of Male Genital Organs, Not Elsewhere Classified Overview

    This group includes inflammatory conditions affecting male genital organs that are not classified elsewhere in the International Classification of Diseases, Tenth Revision, Clinical Modification. It targets infections and noninfectious inflammatory processes of structures such as the testis, epididymis, and other male reproductive tissues. Accurate coding matters for appropriate clinical documentation and reimbursement because it communicates disease site and inflammatory status to payers and downstream users.

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    When to Use

    Use a code from this group for clinical encounters documenting inflammation of the testis, epididymis, or other male genital structures that do not fit into more specific code categories. Select the code that best reflects the documented site, laterality, and acute or chronic status to support accurate clinical and billing records.

    ICD-10-CM Codes

    6 rows

    ICD-10-CM CodeDescription
    N49.0Inflammatory disorders of seminal vesicle
    N49.1Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
    N49.2Inflammatory disorders of scrotum
    N49.3Fournier gangrene
    N49.8Inflammatory disorders of other specified male genital organs
    N49.9Inflammatory disorder of unspecified male genital organ

    DRG Codes

    2 rows

    DRG CodeDescription
    727Inflammation of the Male Reproductive System with MCC
    728Inflammation of the Male Reproductive System without MCC

    Typical Clinical Scenarios

    • A young adult male presents to urgent care with sudden onset unilateral scrotal pain, swelling, and erythema after a week of dysuria and fever. Physical exam shows tender, swollen epididymis without systemic sepsis; ultrasound confirms epididymal inflammation consistent with acute epididymitis. A code from this group is assigned to capture the acute inflammatory condition of the epididymis. Typical codes: N49.2
    • A middle-aged man with known chronic lower urinary tract symptoms and intermittent perineal discomfort follows up in clinic for persistent scrotal fullness and dull ache lasting months despite previous antibiotic courses. Clinical assessment suggests chronic epididymitis/orchitis as a long-standing inflammatory process related to prior infection or persistent reflux; a chronic inflammatory code from the group is used to document ongoing disease management. Typical codes: N49.3, N49.9
    • An older male hospitalized for urinary retention due to prostatic hypertrophy develops acute scrotal pain and purulent drainage from the scrotal skin; exam and cultures indicate bacterial orchitis with overlying scrotal cellulitis as a complication of ascending urinary tract infection. An inflammatory diagnosis code from this group is assigned to capture the orchitis component as a complication/comorbidity of the primary urinary condition. Typical codes: N49.0, N49.8

    Related Codes

    N40-BENIGN-PROSTATIC-HYPERPLASIA

    ICD-10-CM Code For Benign Prostatic Hyperplasia: Group Overview

    N42-OTHER-AND-UNSPECIFIED-PROSTATE-DISORDERS

    ICD-10-CM Code For Other And Unspecified Disorders Of Prostate: Group Overview

    N43-HYDROCELE-AND-SPERMATOCELE

    ICD-10-CM Code For Hydrocele And Spermatocele: Group Overview

    N44-NONINFLAMMATORY-DISORDERS-OF-TESTIS

    ICD-10-CM Code For Noninflammatory Disorders Of Testis: Group Overview

    N45-ORCHITIS-AND-EPIDIDYMITIS

    ICD-10-CM Code For Orchitis And Epididymitis: Group Overview

    N46-MALE-INFERTILITY

    ICD-10-CM Code For Male Infertility: Group Overview

    N47-DISORDERS-OF-PREPUCE

    ICD-10-CM Code For Disorders Of Prepuce: Group Overview

    N48-OTHER-DISORDERS-OF-PENIS

    ICD-10-CM Code For Other Disorders Of Penis: Group Overview

    N50-OTHER-AND-UNSPECIFIED-MALE-GENITAL-DISORDERS

    ICD-10-CM Code For Other And Unspecified Disorders Of Male Genital Organs: Group Overview

    N51-DISORDERS-OF-MALE-GENITAL-ORGANS

    ICD-10-CM Code For Disorders Of Male Genital Organs In Diseases Classified Elsewhere: Group Overview

    Showing 1–10 of 12

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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