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    v1.0.28
    OpenPayerBilling CodesDiseases of male genital organsICD-10-CM n46-male-infertility
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    ICD-10-CM Code For Male Infertility: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group N46 includes diagnoses for male infertility such as oligospermia, azoospermia, and other specified or unspecified infertility of the male reproductive system. These ICD-10-CM diagnosis codes are used to document clinical scenarios involving impaired sperm production, motility, or function, capturing severity and organ-specific involvement relevant to male reproductive health. Accurate coding within the ICD-10-CM N46 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM N46: Male Infertility Overview

    The diagnoses in this group represent disorders of male reproductive function that impair fertility, including oligospermia, azoospermia, and unspecified male infertility. These conditions target the male genital organs and reproductive system. Accurate coding is important for reflecting clinical complexity and for correct reimbursement processing.

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    When to Use

    Use a code from this group when documenting a clinical diagnosis of male infertility based on evaluation such as semen analysis and clinical assessment. Select the code that best reflects the documented diagnosis, specifying the type of sperm abnormality or using unspecified codes when details are not available.

    ICD-10-CM Codes

    16 rows

    ICD-10-CM CodeDescription
    N46.01Organic azoospermia
    N46.021Azoospermia due to drug therapy
    N46.022Azoospermia due to infection
    N46.023Azoospermia due to obstruction of efferent ducts
    N46.024Azoospermia due to radiation
    N46.025Azoospermia due to systemic disease
    N46.029Azoospermia due to other extratesticular causes
    N46.11Organic oligospermia
    N46.121Oligospermia due to drug therapy
    N46.122Oligospermia due to infection
    N46.123Oligospermia due to obstruction of efferent ducts
    N46.124Oligospermia due to radiation
    N46.125Oligospermia due to systemic disease
    N46.129Oligospermia due to other extratesticular causes
    N46.8Other male infertility
    N46.9Male infertility, unspecified

    DRG Codes

    2 rows

    DRG CodeDescription
    729Other Male Reproductive System Diagnoses with CC/MCC
    730Other Male Reproductive System Diagnoses without CC/MCC

    Typical Clinical Scenarios

    • A 29-year-old man presents to a reproductive endocrinology clinic with a 12-month history of inability to conceive with his partner; history and physical reveal prior mumps orchitis and semen analysis shows azoospermia. Evaluation identifies obstructive features on scrotal ultrasound and absent vas deferens on exam, leading to assignment of a male infertility diagnosis related to the identified cause. Typical codes: N46.121, N46.129
    • A 38-year-old man with a history of varicocele and progressive oligospermia on serial semen analyses seeks fertility evaluation; symptoms are chronic and have gradually worsened over several years prompting endocrine and urologic workup. A diagnosis from this group is used to characterize his reduced sperm count contributing to couple infertility and to guide specialty management. Typical codes: N46.122, N46.11
    • A 35-year-old male is evaluated emergently after acute scrotal pain and swelling due to testicular torsion; in the postoperative follow-up he is found to have impaired spermatogenesis and new-onset infertility attributed as a complication of the ischemic event. A code from the group is assigned to capture infertility as a sequela of the acute testicular injury. Typical codes: N46.023, N46.9

    Related Codes

    N40-BENIGN-PROSTATIC-HYPERPLASIA

    ICD-10-CM Code For Benign Prostatic Hyperplasia: Group Overview

    N42-OTHER-AND-UNSPECIFIED-PROSTATE-DISORDERS

    ICD-10-CM Code For Other And Unspecified Disorders Of Prostate: Group Overview

    N43-HYDROCELE-AND-SPERMATOCELE

    ICD-10-CM Code For Hydrocele And Spermatocele: Group Overview

    N44-NONINFLAMMATORY-DISORDERS-OF-TESTIS

    ICD-10-CM Code For Noninflammatory Disorders Of Testis: Group Overview

    N45-ORCHITIS-AND-EPIDIDYMITIS

    ICD-10-CM Code For Orchitis And Epididymitis: Group Overview

    N47-DISORDERS-OF-PREPUCE

    ICD-10-CM Code For Disorders Of Prepuce: Group Overview

    N48-OTHER-DISORDERS-OF-PENIS

    ICD-10-CM Code For Other Disorders Of Penis: Group Overview

    N49-INFLAMMATORY-DISORDERS-MALE-GENITAL

    ICD-10-CM Code For Inflammatory Disorders Of Male Genital Organs, Not Elsewhere Classified: Group Overview

    N50-OTHER-AND-UNSPECIFIED-MALE-GENITAL-DISORDERS

    ICD-10-CM Code For Other And Unspecified Disorders Of Male Genital Organs: Group Overview

    N51-DISORDERS-OF-MALE-GENITAL-ORGANS

    ICD-10-CM Code For Disorders Of Male Genital Organs In Diseases Classified Elsewhere: Group Overview

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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