Loading...

    Explore
    • Policy Monitoring
    • Live Policy Feed
    • Billing Codes
    • NPI Medicare & Medicaid
    • Healthcare Providers
    • Health Insurance Payers
    • States
    • Service Lines
    • Taxonomy Codes
    Lookup tools
    • Billing Code Lookup
    • CPT Modifier Lookup
    • Provider Taxonomy Code Lookup
    • Healthcare Provider & Facility Lookup
    • Health Insurance Payer Lookup
    • Payer Contact Directory

    Policy & Benchmark Tools

    • Prior Authorization Lookup
    • Coverage Criteria Lookup
    • Timely Filing Lookup
    • Billing Code Reimbursement Rates
    • Payer Comparison Dashboard
    • Facility Comparison Dashboard
    • All tools

    Company

    • About OpenPayer
    • Data Sources
    • Trek Health
    OpenPayerby Trek Health
    LinkedInYouTube

    © 2026 Trek Health. All rights reserved.

    OpenPayer is built and maintained by Trek Health.

    v1.0.28
    OpenPayerBilling CodesSpondylopathiesICD-10-CM m45-ankylosing-spondylitis
    Ask Trek AI about this page

    ICD-10-CM Code For Ankylosing Spondylitis: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group M45 includes ankylosing spondylitis and related inflammatory spondylopathies primarily affecting the spine and sacroiliac joints, often with possible extra‑articular involvement. These ICD-10-CM diagnosis codes are used to document clinical scenarios such as active inflammatory back pain, progressive spinal involvement, and associated systemic manifestations like uveitis or enthesitis, capturing disease severity and organ involvement. Accurate coding within the ICD-10-CM M45 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

    Customize your policy alerts

    Sign up for ICD-10-CM Code For Ankylosing Spondylitis: Group Overview policy alerts

    Get alerted when relevant policies change without checking for updates manually.

    Monitor payer policy activity

    Receive email alerts as soon as relevant payer policies are published or updated.

    ICD-10-CM M45: Ankylosing Spondylitis Overview

    The ICD-10-CM M45 group represents ankylosing spondylitis and related spondylopathies primarily affecting the axial skeleton, including the sacroiliac joints and spine. These diagnoses describe inflammatory, progressive conditions that can lead to reduced spinal mobility and extra‑articular manifestations. Accurate coding is important to reflect disease severity and complications, which supports correct reimbursement and continuity of care.

    Table of contents

    Progress1 / 5

    Explore openpayer tools

    • Billing CodesCPT, HCPCS, DRG & more
    • Reimbursement RatesCommercial vs. Medicare rate reports
    • ProvidersHospitals & facilities
    • PayersPlans & market footprint
    • Taxonomy CodesNUCC specialty codes
    • ModifiersCPT modifiers & usage
    • Prior AuthorizationPA policies by payer & drug
    • Timely FilingFiling deadlines by payer
    • Coverage CriteriaMedical necessity by payer
    • Payer ContactsClaims, PA & appeals contacts
    View all tools

    When to Use

    Use a code from this group when a clinician documents a diagnosis of ankylosing spondylitis or a related inflammatory spondylopathy affecting the axial skeleton. Select the specific code that matches the documented disease location, laterality if applicable, and any noted complications or extra‑articular manifestations.

    ICD-10-CM Codes

    20 rows

    ICD-10-CM CodeDescription
    M45.0Ankylosing spondylitis of multiple sites in spine
    M45.1Ankylosing spondylitis of occipito-atlanto-axial region
    M45.2Ankylosing spondylitis of cervical region
    M45.3Ankylosing spondylitis of cervicothoracic region
    M45.4Ankylosing spondylitis of thoracic region
    M45.5Ankylosing spondylitis of thoracolumbar region
    M45.6Ankylosing spondylitis lumbar region
    M45.7Ankylosing spondylitis of lumbosacral region
    M45.8Ankylosing spondylitis sacral and sacrococcygeal region
    M45.9Ankylosing spondylitis of unspecified sites in spine
    M45.A0Non-radiographic axial spondyloarthritis of unspecified sites in spine
    M45.A1Non-radiographic axial spondyloarthritis of occipito-atlanto-axial region
    M45.A2Non-radiographic axial spondyloarthritis of cervical region
    M45.A3Non-radiographic axial spondyloarthritis of cervicothoracic region
    M45.A4Non-radiographic axial spondyloarthritis of thoracic region
    M45.A5Non-radiographic axial spondyloarthritis of thoracolumbar region
    M45.A6Non-radiographic axial spondyloarthritis of lumbar region
    M45.A7Non-radiographic axial spondyloarthritis of lumbosacral region
    M45.A8Non-radiographic axial spondyloarthritis of sacral and sacrococcygeal region
    M45.ABNon-radiographic axial spondyloarthritis of multiple sites in spine

    DRG Codes

    3 rows

    DRG CodeDescription
    545Connective Tissue Disorders with MCC
    546Connective Tissue Disorders with CC
    547Connective Tissue Disorders without CC/MCC

    Related Codes

    M46-OTHER-INFLAMMATORY-SPONDYLOPATHIES

    ICD-10-CM Code For Other Inflammatory Spondylopathies: Group Overview

    M47-SPONDYLOSIS

    ICD-10-CM Code For Spondylosis: Group Overview

    M48-OTHER-SPONDYLOPATHIES

    ICD-10-CM Code For Other Spondylopathies: Group Overview

    M49-SPONDYLOPATHIES-IN-DISEASES-CLASSIFIED-ELSEWHERE

    ICD-10-CM Code For Spondylopathies In Diseases Classified Elsewhere: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
    Published by

    Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.