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    v1.0.28
    OpenPayerBilling CodesUrticaria and erythemaICD-10-CM l52-erythema-nodosum
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    ICD-10-CM Code For Erythema Nodosum: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group L52 includes inflammatory panniculitis presenting as tender, erythematous nodules most commonly on the lower legs and covers erythema nodosum associated with infectious, drug-related, and systemic inflammatory causes. These ICD-10-CM diagnosis codes are used to document clinical presentations of subcutaneous inflammatory nodules, capturing disease distribution, associated triggers, and clinical complexity relevant to dermatologic and systemic involvement. Accurate coding within the ICD-10-CM L52 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM L52: Erythema Nodosum Overview

    Erythema nodosum represents an inflammatory condition of the subcutaneous fat characterized by tender, red nodules typically on the anterior aspects of the lower extremities. The diagnoses in this group target cutaneous inflammatory processes often associated with systemic triggers such as infections, medications, or systemic inflammatory diseases. Accurate coding matters for reimbursement because it links clinical documentation to the appropriate diagnosis group, supporting correct claim processing and resource allocation.

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    When to Use

    Use a code from this group when clinical documentation describes tender, erythematous subcutaneous nodules consistent with erythema nodosum. Select the code when the diagnosis is established and any known associated triggers or systemic associations are documented.

    ICD-10-CM Codes

    1 rows

    ICD-10-CM CodeDescription
    L52Erythema nodosum

    DRG Codes

    2 rows

    DRG CodeDescription
    595Major Skin Disorders with MCC
    596Major Skin Disorders without MCC

    Typical Clinical Scenarios

    • A 28-year-old woman presents to urgent care with sudden onset of multiple tender, warm, erythematous nodules on the anterior aspects of both lower legs accompanied by low-grade fever and recent history of a streptococcal pharyngitis two weeks earlier. The clinician documents the acute inflammatory panniculitis with characteristic exam findings and assigns a diagnosis from this group to capture the primary dermatologic process prompting evaluation and symptomatic treatment. Typical codes: L52
    • A 45-year-old patient with Crohn disease is seen in outpatient dermatology for recurrent, painful subcutaneous nodules on the shins that have persisted intermittently for several months despite control of gastrointestinal symptoms. Because the skin lesions represent a known extraintestinal manifestation of the patient’s chronic inflammatory bowel disease, the dermatologist records a code from this group as a comorbid dermatologic diagnosis affecting management. Typical codes: L52
    • A 60-year-old man presents to the emergency department with acute onset of tender, erythematous nodules on the lower extremities and new onset shortness of breath; workup reveals recent initiation of a sulfonamide antibiotic and concern for systemic hypersensitivity. The ED clinician documents the acute cutaneous inflammatory reaction consistent with erythema nodosum and assigns a code from this group to reflect the skin condition under evaluation while investigations for systemic triggers continue. Typical codes: L52

    Related Codes

    L49-EXFOLIATION-DUE-TO-ERYTHEMATOUS-CONDITIONS

    ICD-10-CM Code For Exfoliation Due To Erythematous Conditions: Group Overview

    L50-URTICARIA

    ICD-10-CM Code For Urticaria: Group Overview

    L51-ERYTHEMA-MULTIFORME

    ICD-10-CM Code For Erythema Multiforme: Group Overview

    L53-OTHER-ERYTHEMATOUS-CONDITIONS

    ICD-10-CM Code For Other Erythematous Conditions: Group Overview

    L54-ERYTHEMA-IN-DISEASES-CLASSIFIED-ELSEWHERE

    ICD-10-CM Code For Erythema In Diseases Classified Elsewhere: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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