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    v1.0.28
    OpenPayerBilling CodesDiseases of esophagus, stomach and duodenumICD-10-CM k27-peptic-ulcer-site-unspecified
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    ICD-10-CM Code For Peptic Ulcer Site Unspecified: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group K27 includes peptic ulcer disease codes used when the ulcer site is not specified, covering nonhealing or acute ulcers of the stomach and duodenum without documented anatomic detail. These ICD-10-CM diagnosis codes are used to document clinical scenarios such as ulcer-related pain, bleeding, perforation, or complications where site-specific information is not recorded, capturing disease severity and clinical complexity. Accurate coding within the ICD-10-CM K27 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM K27: Peptic ulcer, Site Unspecified Overview

    The ICD-10-CM K27 group represents peptic ulcer disease where the specific anatomical site (gastric or duodenal) is not documented or specified. These codes target ulcerative lesions of the stomach and proximal small intestine and are part of diseases of the esophagus, stomach and duodenum. Accurate coding matters for clinical records, quality measurement, and appropriate reimbursement because specificity affects severity indicators and claim processing.

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    When to Use

    Use a code from this group when documentation indicates a peptic ulcer but does not specify whether it is gastric or duodenal. Select these codes for encounters addressing ulcer-related symptoms, complications, or management when site-specific documentation is unavailable.

    ICD-10-CM Codes

    9 rows

    ICD-10-CM CodeDescription
    K27.0Acute peptic ulcer, site unspecified, with hemorrhage
    K27.1Acute peptic ulcer, site unspecified, with perforation
    K27.2Acute peptic ulcer, site unspecified, with both hemorrhage and perforation
    K27.3Acute peptic ulcer, site unspecified, without hemorrhage or perforation
    K27.4Chronic or unspecified peptic ulcer, site unspecified, with hemorrhage
    K27.5Chronic or unspecified peptic ulcer, site unspecified, with perforation
    K27.6Chronic or unspecified peptic ulcer, site unspecified, with both hemorrhage and perforation
    K27.7Chronic peptic ulcer, site unspecified, without hemorrhage or perforation
    K27.9Peptic ulcer, site unspecified, unspecified as acute or chronic, without hemorrhage or perforation

    DRG Codes

    8 rows

    DRG CodeDescription
    377Gastrointestinal Hemorrhage with MCC
    378Gastrointestinal Hemorrhage with CC
    379Gastrointestinal Hemorrhage without CC/MCC
    380Complicated Peptic Ulcer with MCC
    381Complicated Peptic Ulcer with CC
    382Complicated Peptic Ulcer without CC/MCC
    383Uncomplicated Peptic Ulcer with MCC
    384Uncomplicated Peptic Ulcer without MCC

    Typical Clinical Scenarios

    • Elderly patient presents to the emergency department with sudden-onset severe epigastric pain, melena, and a drop in hemoglobin; endoscopy shows an actively bleeding gastric ulcer without clear documentation of acute vs chronic and no specified site. A diagnosis from this group is assigned to capture the peptic ulcer causing gastrointestinal hemorrhage when the ulcer location is not specified. Typical codes: K27.0, K27.1
    • Middle-aged patient with a history of long-term NSAID use reports chronic, intermittent epigastric burning and dyspepsia managed medically over months; outpatient evaluation documents a nonhealing peptic ulcer but the precise location (stomach versus duodenum) is not specified. A code from this group is used to code the chronic, nonacute peptic ulcer condition when site is unspecified. Typical codes: K27.4, K27.5
    • Hospitalized patient with sepsis secondary to perforation of a peptic ulcer; imaging confirms free air and peritonitis but operative notes do not specify whether the perforated ulcer arose in the stomach or duodenum. A diagnosis from this group is assigned to reflect the perforated peptic ulcer complication when site is not specified. Typical codes: K27.2, K27.3

    Related Codes

    K20-ESOPHAGITIS

    ICD-10-CM Code For Esophagitis: Group Overview

    K21-GASTRO-ESOPHAGEAL-REFLUX-DISEASE

    ICD-10-CM Code For Gastro-Esophageal Reflux Disease: Group Overview

    K22-OTHER-DISEASES-OF-ESOPHAGUS

    ICD-10-CM Code For Other Diseases Of Esophagus: Group Overview

    K23-DISORDERS-OF-ESOPHAGUS

    ICD-10-CM Code For Disorders Of Esophagus In Diseases Classified Elsewhere: Group Overview

    K25-GASTRIC-ULCER

    ICD-10-CM Code For Gastric Ulcer: Group Overview

    K26-DUODENAL-ULCER

    ICD-10-CM Code For Duodenal Ulcer: Group Overview

    K28-GASTROJEJUNAL-ULCER

    ICD-10-CM Code For Gastrojejunal Ulcer: Group Overview

    K29-GASTRITIS-AND-DUODENITIS

    ICD-10-CM Code For Gastritis And Duodenitis: Group Overview

    K30-FUNCTIONAL-DYSPEPSIA

    ICD-10-CM Code For Functional Dyspepsia: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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