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    OpenPayerBilling CodesDiseases of veins, lymphatic vessels and lymph nodes, not elsewhere classifiedICD-10-CM i81-portal-vein-thrombosis
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    ICD-10-CM Code For Portal Vein Thrombosis: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group I81 includes diagnoses for thrombosis of the portal vein, covering acute and chronic portal vein occlusion and related mesenteric venous involvement that compromise portal circulation. These ICD-10-CM diagnosis codes are used to document clinical scenarios such as acute thrombotic occlusion, chronic portal vein obstruction with portal hypertension, and portal vein thrombosis associated with liver disease or systemic hypercoagulable states, capturing disease severity and organ involvement. Accurate coding within the ICD-10-CM I81 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM I81: Portal Vein Thrombosis Overview

    Portal vein thrombosis diagnoses represent blood clot formation within the portal venous system that can impair hepatic blood flow and cause portal hypertension. These conditions target the portal vein and related mesenteric venous structures and can result from liver disease, malignancy, infection, or prothrombotic states. Accurate coding matters for appropriate clinical documentation and reimbursement because it captures severity, comorbid conditions, and treatment complexity.

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    When to Use

    Use a code from this group when clinical documentation confirms thrombosis or occlusion of the portal vein or related mesenteric venous structures. Codes are applied for acute thrombotic events, chronic portal vein obstruction, and portal vein thrombosis associated with liver disease, malignancy, or hypercoagulable conditions.

    ICD-10-CM Codes

    1 rows

    ICD-10-CM CodeDescription
    I81Portal vein thrombosis

    DRG Codes

    3 rows

    DRG CodeDescription
    441Disorders of Liver Except Malignancy, Cirrhosis or Alcoholic Hepatitis with MCC
    442Disorders of Liver Except Malignancy, Cirrhosis or Alcoholic Hepatitis with CC
    443Disorders of Liver Except Malignancy, Cirrhosis or Alcoholic Hepatitis without CC/MCC

    Typical Clinical Scenarios

    • A middle-aged patient with cirrhosis and portal hypertension presents to the emergency department with sudden onset abdominal pain and fever. Imaging with Doppler ultrasound or contrast CT reveals an acute thrombus occluding the portal vein, accounting for abdominal pain and signs of liver decompensation; the diagnosis is assigned to document the acute portal vein thrombosis as the primary vascular event. Typical codes: I81
    • An outpatient with known prothrombotic disorder (for example, myeloproliferative neoplasm) is followed longitudinally for chronic occlusion of the portal vein after a prior thrombotic episode; they report persistent portal hypertension, splenomegaly, and variceal surveillance needs. The chronic nature of the portal vein occlusion is coded to reflect ongoing sequelae and need for monitoring. Typical codes: I81
    • A hospitalized patient with pancreatitis develops sudden worsening abdominal pain and new ascites; cross-sectional imaging identifies portal vein thrombosis as a complication of the intra-abdominal inflammatory process contributing to organ dysfunction and altered management. The portal vein thrombosis is documented as a comorbidity/complication during this admission. Typical codes: I81

    Related Codes

    I80-PHLEBITIS-AND-THROMBOPHLEBITIS

    ICD-10-CM Code For Phlebitis And Thrombophlebitis: Group Overview

    I82-OTHER-VENOUS-EMBOLISM-AND-THROMBOSIS

    ICD-10-CM Code For Other Venous Embolism And Thrombosis: Group Overview

    I83-VARICOSE-VEINS-OF-LOWER-EXTREMITIES

    ICD-10-CM Code For Varicose Veins Of Lower Extremities: Group Overview

    I85-ESOPHAGEAL-VARICES

    ICD-10-CM Code For Esophageal Varices: Group Overview

    I86-VARICOSE-VEINS-OTHER-SITES

    ICD-10-CM Code For Varicose Veins Of Other Sites: Group Overview

    I87-OTHER-DISORDERS-OF-VEINS

    ICD-10-CM Code For Other Disorders Of Veins: Group Overview

    I88-NONSPECIFIC-LYMPHADENITIS

    ICD-10-CM Code For Nonspecific Lymphadenitis: Group Overview

    I89-OTHER-NONINFECTIVE-LYMPHATIC-DISORDERS

    ICD-10-CM Code For Other Noninfective Disorders Of Lymphatic Vessels And Lymph Nodes: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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