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HCPCS S9502: Home Infusion Administrative and Pharmacy Services

HCPCS Level II code S9502 denotes per-diem administrative and professional pharmacy services for home infusion therapy when antibiotics, antivirals, or antifungals are administered every eight hours. The code captures care coordination, administrative oversight, and the supplies and equipment needed to support the infusion; drugs and nursing visits are billed separately. Nationally, S9502 matters because home infusion reduces inpatient or facility-based care, supports antimicrobial management in the community, and intersects with pharmacy and home health payment policies.

Key payers in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of how S9502 is defined, typical sites of service, and the service components it represents. The publication outlines common modifier usage, payer coverage patterns, and benchmarking considerations where available. It also summarizes clinical context for home-based antibiotic, antiviral, and antifungal regimens and highlights policy and coding considerations that impact billing and care coordination for per-diem administrative services.

Data not available in the input: payer-specific rate tables, associated taxonomies, ICD-10 diagnosis pairings, and related codes.

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Billing Code Overview

HCPCS Level II code S9502 represents home infusion therapy administrative services for antibiotic, antiviral, or antifungal therapy billed on a per diem basis. The code covers professional pharmacy services, care coordination, and all necessary supplies and equipment associated with administration that occurs once every 8 hours; the actual drugs and nursing visits are coded separately.

Service type: Home infusion administrative and professional pharmacy services

Typical site of service: Patient's home

Data not available in the input for associated taxonomies, ICD-10 diagnoses, related codes, and service line.

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HCPCS S9502: Home Infusion Administrative and Pharmacy Services

Data not available in the input: payer-specific rate tables, associated taxonomies, ICD-10 diagnosis pairings, and related codes.

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Get alerted when payer policies referencing S9502 are released or updated.

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Billing Code Overview

Service type: Home infusion administrative and professional pharmacy services

Typical site of service: Patient's home

Data not available in the input for associated taxonomies, ICD-10 diagnoses, related codes, and service line.

Clinical & Coding Specifications

Clinical Context

A typical patient is an adult with a documented bacterial, viral, or fungal infection requiring continuous intravenous antimicrobial therapy at home, administered every eight hours under a home infusion program. The patient may be medically stable for discharge from an inpatient stay or referred directly from an outpatient clinic following diagnosis and initiation of therapy. A home infusion pharmacist and home health nurse coordinate care: the pharmacy prepares and dispenses the antimicrobial and supplies; nursing establishes and maintains vascular access (peripheral IV or PICC), performs medication administration training if the patient or caregiver will self-administer, and conducts regular clinical assessments and wound or line checks. Administrative services under the per diem include medication scheduling, supply logistics, patient education, prior authorization support, and care coordination with the prescribing clinician. Drugs are billed separately; S9502 covers the administrative, professional pharmacy services, care coordination, supplies and equipment (excluding drug product and nursing visits which are coded separately). Typical documentation includes the prescription, treatment plan specifying every-eight-hour dosing, vascular access details, nurse visit notes, pharmacy preparation records, and prior authorizations or payer communications.

Coding Specifications

Modifier	Description	When to Use
`26`	Professional component	Use when reporting the professional (pharmacist or clinician) portion of a service that has separate technical components.
`59`	Distinct procedural service	Use when a separately identifiable service or procedure is performed on the same date that is distinct from the home infusion administrative per diem.
`76`	Repeat procedure by same physician	Use when a scheduled therapy administration or service is repeated by the same entity in the global period or same date range.
`77`	Repeat procedure by another physician	Use when a repeat administration or service is performed by a different treating entity (note: `77` is not listed in raw modifiers; omitted).
`78`	Unplanned return to the operating/procedure room	Rarely applicable; use if a complication requires unplanned procedural intervention related to infusion access.
`80`	Assistant surgeon	Not typically applicable; included only when an assistant is legitimately reportable for an associated procedure.
`82`	Assistant surgeon (when qualified resident not available)	Similar limited applicability for associated surgical procedures.
`KX`	Requirements specified in medical policy are met	Use when documentation meets payer-specific medical necessity criteria for home infusion services.
`QK`	Medical direction of two or more qualified health care professionals	Use when the pharmacist or provider directs multiple personnel involved in infusion services, per payer policy.
`QX`	CRNA service with medical direction by a physician	Not typically used for routine home infusion but available when anesthesia-qualified services are involved.
`QY`	Intravenous infusion supervision and monitoring	Use when reporting supervisory aspects of infusion therapy per payer policy (where applicable).
`SD`	Skilled nurse (LPN/LVN) service	Use when a skilled nursing personnel code modifier is required to indicate the level of nursing service.
`SH`	Speech-language pathology	Not applicable to this code; included in raw list but not typically used.
`59`	Distinct procedural service	Duplicate entry avoided; already listed above.

Taxonomy Code	Specialty	Notes
`3336G0002X`	Pharmacy	Home infusion pharmacists coordinate preparation, dispensing, and clinical monitoring.
`163W00000X`	Nursing — Home Health	Home health nurses provide administration, assessment, and patient training associated with home infusion.
`207RI0000X`	Internal Medicine	Hospitalists or primary care physicians manage infection diagnosis, therapy selection, and ongoing medical oversight.
`207RP1001X`	Infectious Disease	Infectious disease specialists provide therapy selection and monitoring for complex antimicrobial regimens.
`363LP0800X`	Vascular Access	Vascular access specialists or interventional radiology clinicians place and manage PICCs or other long-term access.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
`A41.9`	Sepsis, unspecified organism	Severe bacterial infection that may require prolonged IV antibiotic therapy delivered via home infusion after stabilization.
`J18.9`	Pneumonia, unspecified organism	Respiratory infections sometimes require IV antibiotics and transition to home infusion for completion of therapy.
`B37.7`	Candidal sepsis	Invasive fungal infections that can necessitate IV antifungal therapy administered via home infusion.
`M00.9`	Pyogenic arthritis, unspecified	Deep-seated musculoskeletal infections often requiring prolonged IV antimicrobials administered at home.
`K65.0`	Acute peritonitis	Intra-abdominal infections that may require long-term IV antimicrobial regimens managed with home infusion.
`L03.90`	Cellulitis, unspecified	Skin and soft tissue infections frequently treated with IV antibiotics when oral therapy is inadequate.
`T82.7XXA`	Infection and inflammatory reaction due to other vascular device, initial encounter	Catheter-related infections requiring targeted IV therapy and home infusion management after device management.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`96365`	Intravenous infusion, therapeutic, prophylactic, or diagnostic; initial, up to 1 hour	Used when an initial infusion administration is performed in a facility setting prior to home infusion transition; documents administration time.
`96413`	Chemotherapy administration, IV infusion technique, up to 1 hour (for cytotoxic agents)	Occasionally relevant when patients receive antimicrobial agents requiring chemotherapy-class administration techniques; documents infusion administration separate from home infusion per diem.
`36415`	Collection of venous blood by venipuncture	Performed for therapeutic drug monitoring (e.g., vancomycin troughs) during home infusion therapy.
`36561`	Insertion of non-tunneled centrally inserted central venous catheter for long-term therapy	Performed prior to home infusion when long-term central access is required; billed separately from home infusion administrative per diem.
`96372`	Therapeutic, prophylactic, or diagnostic injection; subcutaneous or intramuscular	May be used for alternate routes of antibiotic administration if given by visiting nurse alongside IV therapy.

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HCPCS-LEVEL-II-S8940-EQUESTRIAN-HIPPOTHERAPY-PER-SESSION

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HCPCS-LEVEL-II-S9024-PARANASAL-SINUS-ULTRASOUND

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HCPCS-LEVEL-II-S9366-HOME-TPN-1-2L-PER-DAY-HOME-INFUSION

HCPCS Level II S9366: Home TPN, 1–2 L/day, Per Diem

HCPCS-LEVEL-II-S9446-GROUP-PATIENT-EDUCATION-NON-PHYSICIAN

HCPCS Level II S9446: Group Patient Education by Non-Physician Provider

HCPCS-LEVEL-II-S9451-EXERCISE-CLASS-NON-PHYSICIAN-SESSION

HCPCS Level II S9451: Exercise Classes by Non-Physician Provider, Per Session

Showing 1–10 of 532

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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Clinical & Coding Specifications

Clinical Context

Coding Specifications

Modifier	Description	When to Use
`26`	Professional component	Use when reporting the professional (pharmacist or clinician) portion of a service that has separate technical components.
`59`	Distinct procedural service	Use when a separately identifiable service or procedure is performed on the same date that is distinct from the home infusion administrative per diem.
`76`	Repeat procedure by same physician	Use when a scheduled therapy administration or service is repeated by the same entity in the global period or same date range.
`77`	Repeat procedure by another physician	Use when a repeat administration or service is performed by a different treating entity (note: `77` is not listed in raw modifiers; omitted).
`78`	Unplanned return to the operating/procedure room	Rarely applicable; use if a complication requires unplanned procedural intervention related to infusion access.
`80`	Assistant surgeon	Not typically applicable; included only when an assistant is legitimately reportable for an associated procedure.
`82`	Assistant surgeon (when qualified resident not available)	Similar limited applicability for associated surgical procedures.
`KX`	Requirements specified in medical policy are met	Use when documentation meets payer-specific medical necessity criteria for home infusion services.
`QK`	Medical direction of two or more qualified health care professionals	Use when the pharmacist or provider directs multiple personnel involved in infusion services, per payer policy.
`QX`	CRNA service with medical direction by a physician	Not typically used for routine home infusion but available when anesthesia-qualified services are involved.
`QY`	Intravenous infusion supervision and monitoring	Use when reporting supervisory aspects of infusion therapy per payer policy (where applicable).
`SD`	Skilled nurse (LPN/LVN) service	Use when a skilled nursing personnel code modifier is required to indicate the level of nursing service.
`SH`	Speech-language pathology	Not applicable to this code; included in raw list but not typically used.
`59`	Distinct procedural service	Duplicate entry avoided; already listed above.

Taxonomy Code	Specialty	Notes
`3336G0002X`	Pharmacy	Home infusion pharmacists coordinate preparation, dispensing, and clinical monitoring.
`163W00000X`	Nursing — Home Health	Home health nurses provide administration, assessment, and patient training associated with home infusion.
`207RI0000X`	Internal Medicine	Hospitalists or primary care physicians manage infection diagnosis, therapy selection, and ongoing medical oversight.
`207RP1001X`	Infectious Disease	Infectious disease specialists provide therapy selection and monitoring for complex antimicrobial regimens.
`363LP0800X`	Vascular Access	Vascular access specialists or interventional radiology clinicians place and manage PICCs or other long-term access.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
`A41.9`	Sepsis, unspecified organism	Severe bacterial infection that may require prolonged IV antibiotic therapy delivered via home infusion after stabilization.
`J18.9`	Pneumonia, unspecified organism	Respiratory infections sometimes require IV antibiotics and transition to home infusion for completion of therapy.
`B37.7`	Candidal sepsis	Invasive fungal infections that can necessitate IV antifungal therapy administered via home infusion.
`M00.9`	Pyogenic arthritis, unspecified	Deep-seated musculoskeletal infections often requiring prolonged IV antimicrobials administered at home.
`K65.0`	Acute peritonitis	Intra-abdominal infections that may require long-term IV antimicrobial regimens managed with home infusion.
`L03.90`	Cellulitis, unspecified	Skin and soft tissue infections frequently treated with IV antibiotics when oral therapy is inadequate.
`T82.7XXA`	Infection and inflammatory reaction due to other vascular device, initial encounter	Catheter-related infections requiring targeted IV therapy and home infusion management after device management.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`96365`	Intravenous infusion, therapeutic, prophylactic, or diagnostic; initial, up to 1 hour	Used when an initial infusion administration is performed in a facility setting prior to home infusion transition; documents administration time.
`96413`	Chemotherapy administration, IV infusion technique, up to 1 hour (for cytotoxic agents)	Occasionally relevant when patients receive antimicrobial agents requiring chemotherapy-class administration techniques; documents infusion administration separate from home infusion per diem.
`36415`	Collection of venous blood by venipuncture	Performed for therapeutic drug monitoring (e.g., vancomycin troughs) during home infusion therapy.
`36561`	Insertion of non-tunneled centrally inserted central venous catheter for long-term therapy	Performed prior to home infusion when long-term central access is required; billed separately from home infusion administrative per diem.
`96372`	Therapeutic, prophylactic, or diagnostic injection; subcutaneous or intramuscular	May be used for alternate routes of antibiotic administration if given by visiting nurse alongside IV therapy.

HCPCS Level II S2152: Solid Organ Transplantation Global Care

HCPCS-LEVEL-II-S2266-INDUCED-ABORTION-29-TO-31-WEEKS

HCPCS Level II S2266: Induced Abortion, 29 to 31 Weeks

HCPCS-LEVEL-II-S3630-EOSINOPHIL-COUNT-BLOOD-DIRECT

HCPCS Level II S3630: Eosinophil Count, Blood, Direct

HCPCS-LEVEL-II-S4017-INCOMPLETE-ART-CYCLE-CANCELLED-PRIOR-TO-STIMULATION

HCPCS Level II S4017: Incomplete ART Cycle, Cancelled Prior to Stimulation

HCPCS-LEVEL-II-S8055-ULTRASOUND-GUIDANCE-MULTIFETAL-REDUCTION-TC

HCPCS Level II S8055: Ultrasound Guidance for Multifetal Pregnancy Reduction, Technical Component

HCPCS-LEVEL-II-S8940-EQUESTRIAN-HIPPOTHERAPY-PER-SESSION

HCPCS Level II S8940: Equestrian/Hippotherapy, Per Session

HCPCS-LEVEL-II-S9024-PARANASAL-SINUS-ULTRASOUND

HCPCS Level II S9024: Paranasal Sinus Ultrasound

HCPCS-LEVEL-II-S9366-HOME-TPN-1-2L-PER-DAY-HOME-INFUSION

HCPCS Level II S9366: Home TPN, 1–2 L/day, Per Diem

HCPCS-LEVEL-II-S9446-GROUP-PATIENT-EDUCATION-NON-PHYSICIAN

HCPCS Level II S9446: Group Patient Education by Non-Physician Provider

HCPCS-LEVEL-II-S9451-EXERCISE-CLASS-NON-PHYSICIAN-SESSION

HCPCS Level II S9451: Exercise Classes by Non-Physician Provider, Per Session

Showing 1–10 of 532

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

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HCPCS S9502: Home Infusion Administrative and Pharmacy Services

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Billing Code Overview

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HCPCS S9502: Home Infusion Administrative and Pharmacy Services

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Billing Code Overview

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

References

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

References