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HCPCS S9367: Home TPN Per Diem, 2–3 Liters/Day

Headline: HCPCS Level II code S9367 defines per diem home infusion TPN for 2–3 liters daily

Lead: HCPCS Level II code S9367 covers comprehensive per diem services for home total parenteral nutrition (TPN) when patients require more than two but no more than three liters per day. The code bundles administrative and professional pharmacy services, care coordination, and standard TPN supplies and equipment; separately reportable items include nonstandard drugs and nursing visits.

What this represents and why it matters: Home infusion TPN supports medically complex patients who require long-term intravenous nutrition outside acute care. A clear national coding designation like S9367 standardizes billing for bundled home infusion services, which affects care coordination, provider reimbursement workflows, and payers' coverage policies.

Key payers covered: Analysis addresses national payers including Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare.

What readers will learn: The publication provides benchmarks and coding guidance context for HCPCS Level II code S9367, summarizes payer coverage patterns and policy considerations, and explains the clinical and operational scope of the service (per diem home TPN for 2–3 L/day). Data not available in the input is identified where applicable.

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Billing Code Overview

HCPCS Level II code S9367 describes home infusion therapy for total parenteral nutrition (TPN) provided on a per diem basis for patients receiving more than two liters but no more than three liters per day. The code bundles administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment, including standard TPN formula components such as lipids and specialty amino acid formulas. Drugs that are separate from the standard formula and nursing visits are not included in this code and are coded separately.

Service type: Home infusion therapy — TPN per diem for 2–3 L/day

Typical site of service: Patient's home (home health/home infusion setting)

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HCPCS S9367: Home TPN Per Diem, 2–3 Liters/Day

Headline: HCPCS Level II code S9367 defines per diem home infusion TPN for 2–3 liters daily

Key payers covered: Analysis addresses national payers including Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare.

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Get alerted when payer policies referencing S9367 are released or updated.

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Billing Code Overview

Service type: Home infusion therapy — TPN per diem for 2–3 L/day

Typical site of service: Patient's home (home health/home infusion setting)

Clinical & Coding Specifications

Clinical Context

A 62-year-old patient with short bowel syndrome secondary to multiple small bowel resections requires long-term home total parenteral nutrition (TPN). The patient receives an established home infusion therapy plan with a daily TPN volume of 2.5 liters. A specialty pharmacy coordinates formulation of a standard TPN formula including lipids and amino acid solutions; parenteral electrolytes and select additive drugs are included as ordered. A pharmacist provides professional services for medication preparation and oversight, and an infusion company supplies the tubing, infusion pump, and disposables. Nursing visits for catheter care and infusion setup are scheduled separately and billed under nursing visit codes. Clinical workflow: physician documents indication and TPN orders and certifies home infusion; pharmacy receives orders, compounds or dispenses per protocol, and communicates administration instructions; home infusion provider arranges delivery and equipment setup; patient or caregiver performs or supervises daily infusion per training; ongoing care coordination occurs between physician, home infusion pharmacy, and home health nurses to monitor weight, labs, electrolytes, and catheter-related complications. Billing uses per diem submission for the TPN administrative and professional pharmacy services and supplies under S9367, with separate claims for nursing visits and any infused medications billed outside the standard formula.

Coding Specifications

Modifier	Description	When to Use
`22`	Increased procedural services	Use when documented complexity of care for TPN management substantially exceeds usual requirements (rare for per diem TPN; document justification).
`26`	Professional component	Use if billing entity reports only the professional pharmacy service component separately from facility or technical services.
`59`	Distinct procedural service	Use when a separately identifiable service or supply unrelated to the routine TPN per diem is provided the same day and meets criteria for distinct reporting.
`62`	Two surgeons	Use if two practitioners with different specialties share responsibility for complex venous access procedures related to TPN placement (applies to surgical claims, not the home infusion per diem).
`76`	Repeat procedure by same physician	Use if an identical administration or service is repeated later same day and payer allows modifier for repeated service.
`78`	Return to operating room for related procedure	Use if patient requires return to OR for complications of central line placement (billed with operative codes, not the per diem).
`52`	Reduced services	Use when services or supplies in the per diem are partially furnished or reduced from standard, with documentation.
`53`	Discontinued procedure	Use if TPN initiation is attempted but discontinued for documented clinical reasons prior to completion.
`KX`	Requirements specified in the medical policy have been met	Use when payer-specific medical necessity criteria for home TPN are met and documented (applicable for payers that accept `KX`).
`QX`	Certified nurse-midwife or clinician performed service	Use when a qualified non-physician clinician bills under their own NPI and scope applies to associated services.
`QY`	Clinical professional services billed under the supervising practitioner	Use for services billed by a billing provider who is legally responsible for the non-physician clinician's services.
`NU`	New equipment	Use when new durable infusion equipment is provided as part of the per diem and payer expects separate tracking of new vs replacement equipment.
`TG`	Via gravity infusion	Use if infusion is administered by gravity rather than an infusion pump and payer requires method-specific modifier.
`SD`	Surgical team designation	Use if the surgical team concept applies to an associated procedure (relevant for operative claims related to catheter placement).

Taxonomy Code	Specialty	Notes
`362X00000X`	Vascular Surgery	Manages central venous access and catheter placement for long-term TPN.
`174500000X`	Pharmacy	Clinical infusion pharmacists provide compounding oversight, dose adjustments, and professional services.
`207P00000X`	Internal Medicine	Primary management of underlying condition and overall nutrition plan.
`251B00000X`	Registered Nurse	Home health nurses perform catheter care training and monitoring (visits billed separately).
`208000000X`	Gastroenterology	Manages intestinal failure and indications for chronic TPN support.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
`K90.0`	Celiac disease	Malabsorption leading to intestinal failure and potential need for TPN when severe.
`K90.3`	Pancreatic steatorrhea	Severe exocrine insufficiency contributing to malnutrition managed with parenteral support.
`K91.89`	Other postprocedural complications and disorders of digestive system	Postoperative complications (e.g., short bowel) resulting in TPN dependence.
`K91.83`	Intestinal failure	Direct indication for home TPN to provide adequate nutrition when enteral feeding is not possible.
`E43`	Unspecified severe protein-calorie malnutrition	Clinical scenario where TPN may be indicated when enteral nutrition is inadequate.
`E44.1`	Moderate protein-calorie malnutrition	May require supplemental or full parenteral nutrition in specific cases.
`Z79.899`	Other long term (current) drug therapy	Used to indicate ongoing long-term therapy context, occasionally used in documentation for chronic TPN regimens.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`36478`	Endovascular placement of tunneled centrally inserted central venous catheter, with subcutaneous port or pump	Used when placement of a tunneled central venous catheter for long-term TPN is performed prior to home infusion initiation.
`36556`	Insertion of non-tunneled central venous catheter, age 5 years or older	Used for temporary central access when immediate short-term parenteral nutrition is required before establishing long-term access.
`36561`	Insertion of tunneled central venous catheter, with subcutaneous port or pump, without subcutaneous port	Alternative code for tunneled catheter placement for chronic TPN access.
`49422`	Placement of tunneled intraperitoneal catheter (e.g., for peritoneal dialysis)	Listed for access procedures related to home infusion therapies; not typical for TPN but relevant when alternative access is used.
`96360`	Intravenous infusion, hydration; initial, 31 minutes to 1 hour	May be used for billing nursing-administered IV infusions associated with supplemental IV therapies; nursing visits are billed separately from the TPN per diem.

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HCPCS-LEVEL-II-S2266-INDUCED-ABORTION-29-TO-31-WEEKS

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HCPCS-LEVEL-II-S3630-EOSINOPHIL-COUNT-BLOOD-DIRECT

HCPCS Level II S3630: Eosinophil Count, Blood, Direct

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HCPCS Level II S4017: Incomplete ART Cycle, Cancelled Prior to Stimulation

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HCPCS-LEVEL-II-S8940-EQUESTRIAN-HIPPOTHERAPY-PER-SESSION

HCPCS Level II S8940: Equestrian/Hippotherapy, Per Session

HCPCS-LEVEL-II-S9024-PARANASAL-SINUS-ULTRASOUND

HCPCS Level II S9024: Paranasal Sinus Ultrasound

HCPCS-LEVEL-II-S9366-HOME-TPN-1-2L-PER-DAY-HOME-INFUSION

HCPCS Level II S9366: Home TPN, 1–2 L/day, Per Diem

HCPCS-LEVEL-II-S9446-GROUP-PATIENT-EDUCATION-NON-PHYSICIAN

HCPCS Level II S9446: Group Patient Education by Non-Physician Provider

HCPCS-LEVEL-II-S9451-EXERCISE-CLASS-NON-PHYSICIAN-SESSION

HCPCS Level II S9451: Exercise Classes by Non-Physician Provider, Per Session

Showing 1–10 of 532

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

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Clinical & Coding Specifications

Clinical Context

Coding Specifications

Modifier	Description	When to Use
`22`	Increased procedural services	Use when documented complexity of care for TPN management substantially exceeds usual requirements (rare for per diem TPN; document justification).
`26`	Professional component	Use if billing entity reports only the professional pharmacy service component separately from facility or technical services.
`59`	Distinct procedural service	Use when a separately identifiable service or supply unrelated to the routine TPN per diem is provided the same day and meets criteria for distinct reporting.
`62`	Two surgeons	Use if two practitioners with different specialties share responsibility for complex venous access procedures related to TPN placement (applies to surgical claims, not the home infusion per diem).
`76`	Repeat procedure by same physician	Use if an identical administration or service is repeated later same day and payer allows modifier for repeated service.
`78`	Return to operating room for related procedure	Use if patient requires return to OR for complications of central line placement (billed with operative codes, not the per diem).
`52`	Reduced services	Use when services or supplies in the per diem are partially furnished or reduced from standard, with documentation.
`53`	Discontinued procedure	Use if TPN initiation is attempted but discontinued for documented clinical reasons prior to completion.
`KX`	Requirements specified in the medical policy have been met	Use when payer-specific medical necessity criteria for home TPN are met and documented (applicable for payers that accept `KX`).
`QX`	Certified nurse-midwife or clinician performed service	Use when a qualified non-physician clinician bills under their own NPI and scope applies to associated services.
`QY`	Clinical professional services billed under the supervising practitioner	Use for services billed by a billing provider who is legally responsible for the non-physician clinician's services.
`NU`	New equipment	Use when new durable infusion equipment is provided as part of the per diem and payer expects separate tracking of new vs replacement equipment.
`TG`	Via gravity infusion	Use if infusion is administered by gravity rather than an infusion pump and payer requires method-specific modifier.
`SD`	Surgical team designation	Use if the surgical team concept applies to an associated procedure (relevant for operative claims related to catheter placement).

Taxonomy Code	Specialty	Notes
`362X00000X`	Vascular Surgery	Manages central venous access and catheter placement for long-term TPN.
`174500000X`	Pharmacy	Clinical infusion pharmacists provide compounding oversight, dose adjustments, and professional services.
`207P00000X`	Internal Medicine	Primary management of underlying condition and overall nutrition plan.
`251B00000X`	Registered Nurse	Home health nurses perform catheter care training and monitoring (visits billed separately).
`208000000X`	Gastroenterology	Manages intestinal failure and indications for chronic TPN support.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
`K90.0`	Celiac disease	Malabsorption leading to intestinal failure and potential need for TPN when severe.
`K90.3`	Pancreatic steatorrhea	Severe exocrine insufficiency contributing to malnutrition managed with parenteral support.
`K91.89`	Other postprocedural complications and disorders of digestive system	Postoperative complications (e.g., short bowel) resulting in TPN dependence.
`K91.83`	Intestinal failure	Direct indication for home TPN to provide adequate nutrition when enteral feeding is not possible.
`E43`	Unspecified severe protein-calorie malnutrition	Clinical scenario where TPN may be indicated when enteral nutrition is inadequate.
`E44.1`	Moderate protein-calorie malnutrition	May require supplemental or full parenteral nutrition in specific cases.
`Z79.899`	Other long term (current) drug therapy	Used to indicate ongoing long-term therapy context, occasionally used in documentation for chronic TPN regimens.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`36478`	Endovascular placement of tunneled centrally inserted central venous catheter, with subcutaneous port or pump	Used when placement of a tunneled central venous catheter for long-term TPN is performed prior to home infusion initiation.
`36556`	Insertion of non-tunneled central venous catheter, age 5 years or older	Used for temporary central access when immediate short-term parenteral nutrition is required before establishing long-term access.
`36561`	Insertion of tunneled central venous catheter, with subcutaneous port or pump, without subcutaneous port	Alternative code for tunneled catheter placement for chronic TPN access.
`49422`	Placement of tunneled intraperitoneal catheter (e.g., for peritoneal dialysis)	Listed for access procedures related to home infusion therapies; not typical for TPN but relevant when alternative access is used.
`96360`	Intravenous infusion, hydration; initial, 31 minutes to 1 hour	May be used for billing nursing-administered IV infusions associated with supplemental IV therapies; nursing visits are billed separately from the TPN per diem.

HCPCS Level II S2152: Solid Organ Transplantation Global Care

HCPCS-LEVEL-II-S2266-INDUCED-ABORTION-29-TO-31-WEEKS

HCPCS Level II S2266: Induced Abortion, 29 to 31 Weeks

HCPCS-LEVEL-II-S3630-EOSINOPHIL-COUNT-BLOOD-DIRECT

HCPCS Level II S3630: Eosinophil Count, Blood, Direct

HCPCS-LEVEL-II-S4017-INCOMPLETE-ART-CYCLE-CANCELLED-PRIOR-TO-STIMULATION

HCPCS Level II S4017: Incomplete ART Cycle, Cancelled Prior to Stimulation

HCPCS-LEVEL-II-S8055-ULTRASOUND-GUIDANCE-MULTIFETAL-REDUCTION-TC

HCPCS Level II S8055: Ultrasound Guidance for Multifetal Pregnancy Reduction, Technical Component

HCPCS-LEVEL-II-S8940-EQUESTRIAN-HIPPOTHERAPY-PER-SESSION

HCPCS Level II S8940: Equestrian/Hippotherapy, Per Session

HCPCS-LEVEL-II-S9024-PARANASAL-SINUS-ULTRASOUND

HCPCS Level II S9024: Paranasal Sinus Ultrasound

HCPCS-LEVEL-II-S9366-HOME-TPN-1-2L-PER-DAY-HOME-INFUSION

HCPCS Level II S9366: Home TPN, 1–2 L/day, Per Diem

HCPCS-LEVEL-II-S9446-GROUP-PATIENT-EDUCATION-NON-PHYSICIAN

HCPCS Level II S9446: Group Patient Education by Non-Physician Provider

HCPCS-LEVEL-II-S9451-EXERCISE-CLASS-NON-PHYSICIAN-SESSION

HCPCS Level II S9451: Exercise Classes by Non-Physician Provider, Per Session

Showing 1–10 of 532

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

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HCPCS S9367: Home TPN Per Diem, 2–3 Liters/Day

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Billing Code Overview

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HCPCS S9367: Home TPN Per Diem, 2–3 Liters/Day

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Billing Code Overview

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

References

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

References